Term Details for "antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent" (GO:0002479) (original) (raw)

Accession

GO:0002479

Name

antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent

Ontology

biological_process

Synonyms

TAP-dependent antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent exogenous peptide antigen processing and presentation via MHC class I, exogenous peptide antigen processing and presentation via MHC class I, TAP-dependent, cross presentation, cross-presentation

Alternate IDs

None

Definition

The process in which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC class I protein complex following intracellular transport via a TAP (transporter associated with antigen processing) pathway. The peptide is typically a fragment of a larger exogenous protein which has been degraded within the cell and is dependent on TAP transport from the cytosol to ER for association with the MHC class I molecule. Class I here refers to classical class I molecules.Source: PMID:15224093,GOC:add,PMID:15771591,PMID:16181335

Comment

None

History

See term history for GO:0002479 at QuickGO

Chem. react.

None

Subset

None

Link to all genes and gene products annotated to antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (excluding "regulates").

Link to all direct and indirect annotations to antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (excluding "regulates").

Link to all direct and indirect annotations download (limited to first 10,000) for antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (excluding "regulates").