Term Details for "phospholipase C-activating G protein-coupled receptor signaling pathway" (GO:0007200) (original) (raw)

Accession

GO:0007200

Name

phospholipase C-activating G protein-coupled receptor signaling pathway

Ontology

biological_process

Synonyms

G protein signaling, coupled to IP3 second messenger (phospholipase C activating), G protein signalling, coupled to IP3 second messenger (phospholipase C activating), G-protein coupled receptor signaling pathway coupled to IP3 second messenger, G-protein signaling, coupled to IP3 second messenger (phospholipase C activating), G-protein signalling, coupled to IP3 second messenger (phospholipase C activating), PLC-activating GPCR signaling pathway, phospholipase C-activating G-protein coupled receptor signaling pathway, protein kinase C-activating G protein-coupled receptor signaling pathway, activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger

Alternate IDs

None

Definition

A G protein-coupled receptor signaling pathway in which the signal is transmitted via the activation of phospholipase C (PLC) and a subsequent increase in the intracellular concentration of inositol trisphosphate (IP3) and diacylglycerol (DAG). IP3 regulates the opening of calcium channels in intracellular calcium store, leading to the release of calcium into the cytosol. Calcium and DAG activate protein kinase C (PKC), which in turn activates downstream effectors.Source: GOC:signaling,GOC:dph,GOC:tb,GOC:mah,ISBN:0815316194

Comment

None

History

See term history for GO:0007200 at QuickGO

Chem. react.

None

Subset

None

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