Term Details for "SCF ubiquitin ligase complex" (GO:0019005) (original) (raw)

Accession

GO:0019005

Name

SCF ubiquitin ligase complex

Ontology

cellular_component

Synonyms

CDL1 complex, CRL1 complex, Cul1-RING ubiquitin ligase complex, SCF complex, Skp1/Cul1/F-box protein complex, cullin-RING ligase 1, SCF complex substrate recognition subunit

Alternate IDs

None

Definition

A ubiquitin ligase complex in which a cullin from the Cul1 subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by a Skp1 adaptor and an F-box protein. SCF complexes are involved in targeting proteins for degradation by the proteasome. The best characterized complexes are those from yeast and mammals (with core subunits named Cdc53/Cul1, Rbx1/Hrt1/Roc1).Source: PMID:15688063,PMID:15571813

Comment

None

History

See term history for GO:0019005 at QuickGO

Chem. react.

None

Subset

None

Link to all genes and gene products annotated to SCF ubiquitin ligase complex (excluding "regulates").

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