Term Details for "post-translational protein modification" (GO:0043687) (original) (raw)

Accession

GO:0043687

Name

post-translational protein modification

Ontology

biological_process

Synonyms

PTM, post-translational amino acid modification, post-translational modification, posttranslational amino acid modification, posttranslational modification, posttranslational protein modification

Alternate IDs

None

Definition

The process of covalently altering one or more amino acids in a protein after the protein has been completely translated and released from the ribosome.Source: GOC:jsg

Comment

This term should only be used to annotate a protein modification process that occurs after the protein has been released from the ribosome, and is therefore strictly post-translational. Modification of a free protein (one not attached to a ribosome) and modification of a C-terminal residue are post-translational processes. Some protein modifications occur while the protein is still in the ribosome but before translation has been completed; these modification processes are considered co-translational and should not be annotated using this term.

History

See term history for GO:0043687 at QuickGO

Chem. react.

None

Subset

None

Link to all genes and gene products annotated to post-translational protein modification (excluding "regulates").

Link to all direct and indirect annotations to post-translational protein modification (excluding "regulates").

Link to all direct and indirect annotations download (limited to first 10,000) for post-translational protein modification (excluding "regulates").