Term Details for "positive regulation of release of cytochrome c from mitochondria" (GO:0090200) (original) (raw)

Accession

GO:0090200

Name

positive regulation of release of cytochrome c from mitochondria

Ontology

biological_process

Synonyms

None

Alternate IDs

None

Definition

Any process that increases the rate, frequency or extent of release of cytochrome c from mitochondria, the process in which cytochrome c is enabled to move from the mitochondrial intermembrane space into the cytosol, which is an early step in apoptosis and leads to caspase activation.Source: GOC:dph,GOC:tb,GOC:BHF,GOC:mtg_apoptosis

Comment

The release of cytochrome c from mitochondria is a central event in the signaling phase of the apoptotic process, and it is often used by researchers to monitor this type of cell death. Any event that induces apoptosis will at some point induce the release of cytochrome c from mitochondria. Therefore, this term should only be used to annotate gene products that directly and positively regulate this process.

History

See term history for GO:0090200 at QuickGO

Chem. react.

None

Subset

None

Link to all genes and gene products annotated to positive regulation of release of cytochrome c from mitochondria (excluding "regulates").

Link to all direct and indirect annotations to positive regulation of release of cytochrome c from mitochondria (excluding "regulates").

Link to all direct and indirect annotations download (limited to first 10,000) for positive regulation of release of cytochrome c from mitochondria (excluding "regulates").