Term Details for "execution phase of apoptosis" (GO:0097194) (original) (raw)
Accession
GO:0097194
Name
execution phase of apoptosis
Ontology
biological_process
Synonyms
execution phase of apoptotic process, apoptosis
Alternate IDs
None
Definition
A stage of the apoptotic process that starts with the controlled breakdown of the cell through the action of effector caspases or other effector molecules (e.g. cathepsins, calpains etc.). Key steps of the execution phase are rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died.Source: PMID:21760595,GOC:mtg_apoptosis
Comment
None
History
See term history for GO:0097194 at QuickGO
Chem. react.
None
Subset
None
Link to all genes and gene products annotated to execution phase of apoptosis (excluding "regulates").
Link to all direct and indirect annotations to execution phase of apoptosis (excluding "regulates").
Link to all direct and indirect annotations download (limited to first 10,000) for execution phase of apoptosis (excluding "regulates").