Term Details for "execution phase of apoptosis" (GO:0097194) (original) (raw)

Accession

GO:0097194

Name

execution phase of apoptosis

Ontology

biological_process

Synonyms

execution phase of apoptotic process, apoptosis

Alternate IDs

None

Definition

A stage of the apoptotic process that starts with the controlled breakdown of the cell through the action of effector caspases or other effector molecules (e.g. cathepsins, calpains etc.). Key steps of the execution phase are rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died.Source: PMID:21760595,GOC:mtg_apoptosis

Comment

None

History

See term history for GO:0097194 at QuickGO

Chem. react.

None

Subset

None

Link to all genes and gene products annotated to execution phase of apoptosis (excluding "regulates").

Link to all direct and indirect annotations to execution phase of apoptosis (excluding "regulates").

Link to all direct and indirect annotations download (limited to first 10,000) for execution phase of apoptosis (excluding "regulates").