InteRD: The Integrated and Robust Deconvolution (original) (raw)
We developed the Integrated and Robust Deconvolution algorithm to infer cell-type proportions from target bulk RNA-seq data. This package is able to effectively integrate deconvolution results from multiple scRNA-seq datasets and calibrates estimates from reference-based deconvolution by taking into account extra biological information as priors. Moreover, the proposed algorithm is robust to inaccurate external information imposed in the deconvolution system.
| Version: | 0.1.1 |
|---|---|
| Depends: | R (≥ 3.5.0), Biobase |
| Imports: | Rcpp (≥ 0.11.0), limSolve, cowplot, ggplot2, pheatmap, stats, DescTools, mgcv, reshape2 |
| Suggests: | knitr, rmarkdown, testthat (≥ 3.0.0) |
| Published: | 2022-08-12 |
| DOI: | 10.32614/CRAN.package.InteRD |
| Author: | Chixiang Chen [cre, aut], Yuk Yee Leung [aut], Matei Lonita [aut], Li-San Wang [aut], Mingyao Li [aut] |
| Maintainer: | Chixiang Chen |
| BugReports: | https://github.com/chencxxy28/InteRD/issues |
| License: | Artistic-2.0 |
| URL: | https://github.com/chencxxy28/InteRD |
| NeedsCompilation: | no |
| Materials: | README NEWS |
| In views: | Omics |
| CRAN checks: | InteRD results |
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