POSTm: Phylogeny-Guided OTU-Specific Association Test for Microbiome Data (original) (raw)

Implements the Phylogeny-Guided Microbiome OTU-Specific Association Test method, which boosts the testing power by adaptively borrowing information from phylogenetically close OTUs (operational taxonomic units) of the target OTU. This method is built on a kernel machine regression framework and allows for flexible modeling of complex microbiome effects, adjustments for covariates, and can accommodate both continuous and binary outcomes.

Documentation:

Downloads:

Linking:

Please use the canonical formhttps://CRAN.R-project.org/package=POSTmto link to this page.