noise: Estimation of Intrinsic and Extrinsic Noise from Single-Cell Data (original) (raw)
Functions to calculate estimates of intrinsic and extrinsic noise from the two-reporter single-cell experiment, as in Elowitz, M. B., A. J. Levine, E. D. Siggia, and P. S. Swain (2002) Stochastic gene expression in a single cell. Science, 297, 1183-1186. Functions implement multiple estimators developed for unbiasedness or min Mean Squared Error (MSE) in Fu, A. Q. and Pachter, L. (2016). Estimating intrinsic and extrinsic noise from single-cell gene expression measurements. Statistical Applications in Genetics and Molecular Biology, 15(6), 447-471.
| Version: | 1.0.2 |
|---|---|
| Depends: | R (≥ 2.10) |
| Imports: | preprocessCore |
| Published: | 2024-02-29 |
| DOI: | 10.32614/CRAN.package.noise |
| Author: | Audrey Qiuyan Fu and Lior Pachter |
| Maintainer: | Audrey Q. Fu |
| License: | GPL-2 | GPL-3 [expanded from: GPL (≥ 2)] |
| NeedsCompilation: | no |
| CRAN checks: | noise results |
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