2-C-Methyl-D-erythritol-2,4-cyclopyrophosphate (original) (raw)
Le 2-C-méthyl-D-érythritol-2,4-cyclopyrophosphate (MEcPP) est un intermédiaire de la voie du méthylérythritol phosphate (voie « non mévalonique ») de biosynthèse des isoprénoïdes.
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| dbo:abstract | 2-C-Methyl-d-erythritol-2,4-cyclopyrophosphate (MEcPP) (also 2-C-Methyl-d-erythritol-2,4-cyclodiphosphate) is an intermediate in the MEP pathway (non-mevalonate) of isoprenoid precursor biosynthesis. MEcPP is produced by MEcPP synthase (IspF) and is a substrate for HMB-PP synthase (IspG). Under conditions of oxidative stress, MEcPP accumulates in certain bacteria. MEcPP releases histone-like proteins from DNA, triggering nucleoid decondensation in Chlamydia trachomatis during the process of terminal differentiation. Abiotic stresses to plants, including wounding and excessive high-light exposure, lead to an increase in MEcPP accumulation in chloroplasts. Transported from the chloroplast to the plant cell nucleus, MEcPP engages in retrograde signalling that leads to the specific induction of nuclear-encoded stress-response genes. (en) Le 2-C-méthyl-D-érythritol-2,4-cyclopyrophosphate (MEcPP) est un intermédiaire de la voie du méthylérythritol phosphate (voie « non mévalonique ») de biosynthèse des isoprénoïdes. (fr) 2-C-メチル-D-エリトリトール-2,4-シクロピロリン酸（2-C-メチル-D-エリトリトール-2,4-シクロピロリンさん、2-C-Methyl-D-erythritol-2,4-cyclopyrophosphate、MEcPP）は、非メバロン酸経路の中間生成物の一つ。2-メチルブタン-1,2,3,4-テトラール-2,4-シクロピロリン酸（2-methyl-butan-1,2,3,4-tetraol-2,4-cyclopyrophosphate）ともいう。 非メバロン酸経路では、によって4-ジホスホシチジル-2-C-メチル-D-エリトリトール-2-リン酸から合成される。 (ja) 2-C-메틸에리트리톨 2,4-사이클로피로인산(영어: 2-C-methylerythritol 2,4-cyclopyrophosphate, MEcPP) 또는 2-C-메틸에리트리톨 2,4-사이클로이인산(영어: 2-C-methylerythritol 2,4-cyclodiphosphate)은 아이소프레노이드 전구체 생합성의 비메발론산 경로에서의 대사 중간생성물이다. 2-C-메틸에리트리톨 2,4-사이클로피로인산(MEcPP)은 (MEcPP 생성효소, IspF)에 의해 생성된다. 2-C-메틸에리트리톨 2,4-사이클로피로인산은 (HMB-PP 생성효소, IspG)의 기질이다. 산화적 스트레스 조건 하에서 2-C-메틸에리트리톨 2,4-사이클로피로인산은 특정 세균에 축적된다. 2-C-메틸에리트리톨 2,4-사이클로피로인산은 DNA로부터 히스톤 유사 단백질을 방출하여, 클라미디아 트라코마티스(Chlamydia trachomatis)의 최종 분화 과정에서 핵양체의 탈응축을 유발한다. 상처와 과도한 빛에 대한 노출을 포함한 식물의 스트레스는 엽록체에 2-C-메틸에리트리톨 2,4-사이클로피로인산의 축적을 증가시킨다. 엽록체에서 식물 세포 핵으로 운반된 2-C-메틸에리트리톨 2,4-사이클로피로인산은 역방향 신호전달에 관여하여 핵에 암호화되어 있는 스트레스 반응 유전자들을 특이적으로 발현시킨다. (ko) |
| dbo:iupacName | (6S,7R)-2,4,7-Trihydroxy-6-(hydroxymethyl)-6-methyl-1,3,5,2λ5,4λ5-trioxadiphosphocane-2,4-dione (en) |
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| dbp:imagealt | Skeletal formula of 2-C-methyl-D-erythritol-2,4-cyclodiphosphate (en) Ball-and-stick model of the 2-C-methyl-D-erythritol-2,4-cyclodiphosphate molecule (en) |
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| rdfs:comment | Le 2-C-méthyl-D-érythritol-2,4-cyclopyrophosphate (MEcPP) est un intermédiaire de la voie du méthylérythritol phosphate (voie « non mévalonique ») de biosynthèse des isoprénoïdes. (fr) 2-C-メチル-D-エリトリトール-2,4-シクロピロリン酸（2-C-メチル-D-エリトリトール-2,4-シクロピロリンさん、2-C-Methyl-D-erythritol-2,4-cyclopyrophosphate、MEcPP）は、非メバロン酸経路の中間生成物の一つ。2-メチルブタン-1,2,3,4-テトラール-2,4-シクロピロリン酸（2-methyl-butan-1,2,3,4-tetraol-2,4-cyclopyrophosphate）ともいう。 非メバロン酸経路では、によって4-ジホスホシチジル-2-C-メチル-D-エリトリトール-2-リン酸から合成される。 (ja) 2-C-Methyl-d-erythritol-2,4-cyclopyrophosphate (MEcPP) (also 2-C-Methyl-d-erythritol-2,4-cyclodiphosphate) is an intermediate in the MEP pathway (non-mevalonate) of isoprenoid precursor biosynthesis. MEcPP is produced by MEcPP synthase (IspF) and is a substrate for HMB-PP synthase (IspG). (en) 2-C-메틸에리트리톨 2,4-사이클로피로인산(영어: 2-C-methylerythritol 2,4-cyclopyrophosphate, MEcPP) 또는 2-C-메틸에리트리톨 2,4-사이클로이인산(영어: 2-C-methylerythritol 2,4-cyclodiphosphate)은 아이소프레노이드 전구체 생합성의 비메발론산 경로에서의 대사 중간생성물이다. 2-C-메틸에리트리톨 2,4-사이클로피로인산(MEcPP)은 (MEcPP 생성효소, IspF)에 의해 생성된다. 2-C-메틸에리트리톨 2,4-사이클로피로인산은 (HMB-PP 생성효소, IspG)의 기질이다. (ko) |
| rdfs:label | 2-C-Methyl-D-erythritol-2,4-cyclopyrophosphate (en) 2-C-Méthyl-D-érythritol-2,4-cyclopyrophosphate (fr) 2-C-메틸에리트리톨 2,4-사이클로피로인산 (ko) 2-C-メチル-D-エリトリトール-2,4-シクロピロリン酸 (ja) |
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