| dbo:abstract |
2-Methyl-3,4-methylenedioxyamphetamine (2-methyl-MDA) is an entactogen and psychedelic drug of the amphetamine class. It acts as a selective serotonin releasing agent (SSRA), with IC50 values of 93nM, 12,000nM, and 1,937nM for serotonin, dopamine, and norepinephrine efflux. 2-Methyl-MDA is more potent than MDA and 5-methyl-MDA. However, it is slightly more selective for serotonin over dopamine and norepinephrine release in comparison to 5-methyl-MDA. (en) La 2-metil-3,4-metilendiossiamestamina (2-metil-MDA) è una sostanza utilizzata come stupefacente o droga facente parte della classe delle anfetamine. Agisce come agente di rilascio della serotonina (SSRA) selettivo, con valori di IC 50 di 93nM, 12.000nM e 1.937nM per l'efflusso di serotonina, dopamina e norepinefrina. La 2-Metil-MDA è più potente della MDA, sebbene non sia potente quanto la 5-Metil-MDA. Tuttavia, è leggermente più selettiva per la serotonina rispetto al rilascio di dopamina e norepinefrina rispetto al 5-metil-MDA. (it) |
| dbo:casNumber |
(HCl) 691876-73-0 |
| dbo:chEMBL |
6391 |
| dbo:pubchem |
10104064 |
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none (en) |
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dbr:Mouth |
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| gold:hypernym |
dbr:Entactogen |
| rdf:type |
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| rdfs:comment |
2-Methyl-3,4-methylenedioxyamphetamine (2-methyl-MDA) is an entactogen and psychedelic drug of the amphetamine class. It acts as a selective serotonin releasing agent (SSRA), with IC50 values of 93nM, 12,000nM, and 1,937nM for serotonin, dopamine, and norepinephrine efflux. 2-Methyl-MDA is more potent than MDA and 5-methyl-MDA. However, it is slightly more selective for serotonin over dopamine and norepinephrine release in comparison to 5-methyl-MDA. (en) La 2-metil-3,4-metilendiossiamestamina (2-metil-MDA) è una sostanza utilizzata come stupefacente o droga facente parte della classe delle anfetamine. Agisce come agente di rilascio della serotonina (SSRA) selettivo, con valori di IC 50 di 93nM, 12.000nM e 1.937nM per l'efflusso di serotonina, dopamina e norepinefrina. La 2-Metil-MDA è più potente della MDA, sebbene non sia potente quanto la 5-Metil-MDA. Tuttavia, è leggermente più selettiva per la serotonina rispetto al rilascio di dopamina e norepinefrina rispetto al 5-metil-MDA. (it) |
| rdfs:label |
2-Methyl-MDA (en) 2-Metil-MDA (it) |
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freebase:2-Methyl-MDA yago-res:2-Methyl-MDA http://www4.wiwiss.fu-berlin.de/drugbank/resource/drugs/DB01566 wikidata:2-Methyl-MDA dbpedia-it:2-Methyl-MDA dbpedia-sh:2-Methyl-MDA dbpedia-sr:2-Methyl-MDA https://global.dbpedia.org/id/4GYXP |
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