21-hydroxysteroid dehydrogenase (NAD+) (original) (raw)

In enzymology, a 21-hydroxysteroid dehydrogenase (NAD+) (EC 1.1.1.150) is an enzyme that catalyzes the chemical reaction pregnan-21-ol + NAD+ pregnan-21-al + NADH + H+ Thus, the two substrates of this enzyme are and NAD+, whereas its 3 products are , NADH, and H+. This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is 21-hydroxysteroid:NAD+ 21-oxidoreductase. This enzyme is also called 21-hydroxysteroid dehydrogenase (NAD+).