8-hydroxyfuranocoumarin 8-O-methyltransferase (original) (raw)

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8-ヒドロキシフラノクマリン 8-O-メチルトランスフェラーゼ(8-hydroxyfuranocoumarin 8-O-methyltransferase、EC 2.1.1.70)は、以下の化学反応を触媒する酵素である。 (1) S-アデノシル-L-メチオニン + 8-ヒドロキシフラノクマリンS-アデノシル-L-ホモシステイン + 8-メトキシフラノクマリン（一般的な反応）(2) S-アデノシル-L-メチオニン + キサントトキソールS-アデノシル-L-ホモシステイン + キサントトキシン この酵素は、転移酵素、特に1炭素基を転移させるメチルトランスフェラーゼのファミリーに属する。系統名は、S-アデノシル-L-メチオニン:8-ヒドロキシフラノクマリン 8-O-メチルトランスフェラーゼ(S-adenosyl-L-methionine:8-hydroxyfurocoumarin 8-O-methyltransferase)である。 この酵素は、キサントトキソールをに変換する。

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dbo:abstract 8-hydroxyfuranocoumarin 8-O-methyltransferase (EC 2.1.1.70, furanocoumarin 8-methyltransferase, furanocoumarin 8-O-methyl-transferase, xanthotoxol 8-O-methyltransferase, XMT, SAM:xanthotoxol O-methyltransferase, S-adenosyl-L-methionine:8-hydroxyfuranocoumarin 8-O-methyltransferase, xanthotoxol methyltransferase, xanthotoxol O-methyltransferase, S-adenosyl-L-methionine:xanthotoxol O-methyltransferase, S-adenosyl-L-methionine-xanthotoxol O-methyltransferase) is an enzyme with systematic name S-adenosyl-L-methionine:8-hydroxyfurocoumarin 8-O-methyltransferase. This enzyme catalyses the following chemical reaction (1) S-adenosyl-L-methionine + an 8-hydroxyfurocoumarin S-adenosyl-L-homocysteine + an 8-methoxyfurocoumarin (general reaction)(2) S-adenosyl-L-methionine + xanthotoxol S-adenosyl-L-homocysteine + xanthotoxin 8-hydroxyfuranocoumarin 8-O-methyltransferase converts xanthotoxol into xanthotoxin. (en) La 8-idrossifuranocumarina 8-O-metiltransferasi (numero EC 2.1.1.70) è un enzima appartenente alla classe delle transferasi, che catalizza la seguente reazione: S-adenosil-L-metionina + una 8-idrossifurocumarina ⇄ S-adenosil-L-omocisteina + una 8-metossifurocumarina (reazione generale);;S-adenosil-L-metionina + xantoxolo ⇄ S-adenosil-L-omocisteina + xantossina L'enzima converte lo xantoxolo in xantossina, che ha un potenziale terapeutico nel trattamento della psoriasi, dal momento che ha attività fotosensibilizzante ed antiproliferativa. L'enzima metila il gruppo 8-ossidrile di alcune idrossi- e metilcumarine, ma ha bassa attività su fenoli non cumarinici. (it) 8-ヒドロキシフラノクマリン 8-O-メチルトランスフェラーゼ(8-hydroxyfuranocoumarin 8-O-methyltransferase、EC 2.1.1.70)は、以下の化学反応を触媒する酵素である。 (1) S-アデノシル-L-メチオニン + 8-ヒドロキシフラノクマリンS-アデノシル-L-ホモシステイン + 8-メトキシフラノクマリン（一般的な反応）(2) S-アデノシル-L-メチオニン + キサントトキソールS-アデノシル-L-ホモシステイン + キサントトキシン この酵素は、転移酵素、特に1炭素基を転移させるメチルトランスフェラーゼのファミリーに属する。系統名は、S-アデノシル-L-メチオニン:8-ヒドロキシフラノクマリン 8-O-メチルトランスフェラーゼ(S-adenosyl-L-methionine:8-hydroxyfurocoumarin 8-O-methyltransferase)である。 この酵素は、キサントトキソールをに変換する。 (ja)
dbo:ecNumber 2.1.1.70
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dbp:iubmbEcNumber 2 (xsd:integer)
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dbp:wikiPageUsesTemplate dbt:EC_number dbt:Enzymes dbt:Infobox_enzyme dbt:MeshName dbt:One_carbon_transferases dbt:Portal_bar dbt:Reflist
dcterms:subject dbc:EC_2.1.1 dbc:Coumarins_metabolism
rdf:type owl:Thing dbo:Biomolecule wikidata:Q206229 wikidata:Q8047 yago:Abstraction100002137 yago:Activator114723079 yago:Catalyst114723628 yago:Chemical114806838 yago:Compound114818238 yago:Enzyme114732946 yago:Macromolecule114944888 yago:Material114580897 yago:Matter100020827 yago:Molecule114682133 yago:OrganicCompound114727670 yago:Part113809207 yago:PhysicalEntity100001930 yago:Protein114728724 yago:Relation100031921 dbo:Enzyme yago:Substance100019613 yago:Thing100002452 yago:Unit109465459
rdfs:comment 8-ヒドロキシフラノクマリン 8-O-メチルトランスフェラーゼ(8-hydroxyfuranocoumarin 8-O-methyltransferase、EC 2.1.1.70)は、以下の化学反応を触媒する酵素である。 (1) S-アデノシル-L-メチオニン + 8-ヒドロキシフラノクマリンS-アデノシル-L-ホモシステイン + 8-メトキシフラノクマリン（一般的な反応）(2) S-アデノシル-L-メチオニン + キサントトキソールS-アデノシル-L-ホモシステイン + キサントトキシン この酵素は、転移酵素、特に1炭素基を転移させるメチルトランスフェラーゼのファミリーに属する。系統名は、S-アデノシル-L-メチオニン:8-ヒドロキシフラノクマリン 8-O-メチルトランスフェラーゼ(S-adenosyl-L-methionine:8-hydroxyfurocoumarin 8-O-methyltransferase)である。 この酵素は、キサントトキソールをに変換する。 (ja) 8-hydroxyfuranocoumarin 8-O-methyltransferase (EC 2.1.1.70, furanocoumarin 8-methyltransferase, furanocoumarin 8-O-methyl-transferase, xanthotoxol 8-O-methyltransferase, XMT, SAM:xanthotoxol O-methyltransferase, S-adenosyl-L-methionine:8-hydroxyfuranocoumarin 8-O-methyltransferase, xanthotoxol methyltransferase, xanthotoxol O-methyltransferase, S-adenosyl-L-methionine:xanthotoxol O-methyltransferase, S-adenosyl-L-methionine-xanthotoxol O-methyltransferase) is an enzyme with systematic name S-adenosyl-L-methionine:8-hydroxyfurocoumarin 8-O-methyltransferase. This enzyme catalyses the following chemical reaction (en) La 8-idrossifuranocumarina 8-O-metiltransferasi (numero EC 2.1.1.70) è un enzima appartenente alla classe delle transferasi, che catalizza la seguente reazione: S-adenosil-L-metionina + una 8-idrossifurocumarina ⇄ S-adenosil-L-omocisteina + una 8-metossifurocumarina (reazione generale);;S-adenosil-L-metionina + xantoxolo ⇄ S-adenosil-L-omocisteina + xantossina (it)
rdfs:label 8-hydroxyfuranocoumarin 8-O-methyltransferase (en) 8-idrossifuranocumarina 8-O-metiltransferasi (it) 8-ヒドロキシフラノクマリン 8-O-メチルトランスフェラーゼ (ja)
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