ACV synthetase (ACVS, L-δ-(α-aminoadipoyl)-L-cysteinyl-D-valine synthetase, N-(5-amino-5-carboxypentanoyl)-L-cysteinyl-D-valine synthase, EC 6.3.2.26) is an enzyme that catalyzes the chemical reaction 3 ATP + L-2-aminohexanedioate + L-cysteine + L-valine + H2O 3 AMP + 3 PPi + N-[L-5-amino-5-carboxypentanoyl]-L-cysteinyl-D-valine The five substrates of this enzyme are ATP, L-2-aminohexanedioate, L-cysteine, L-valine, and H2O, whereas its three products are AMP, diphosphate, and N-[L-5-amino-5-carboxypentanoyl]-L-cysteinyl-D-valine.
| Property |
Value |
| dbo:abstract |
ACV synthetase (ACVS, L-δ-(α-aminoadipoyl)-L-cysteinyl-D-valine synthetase, N-(5-amino-5-carboxypentanoyl)-L-cysteinyl-D-valine synthase, EC 6.3.2.26) is an enzyme that catalyzes the chemical reaction 3 ATP + L-2-aminohexanedioate + L-cysteine + L-valine + H2O 3 AMP + 3 PPi + N-[L-5-amino-5-carboxypentanoyl]-L-cysteinyl-D-valine The five substrates of this enzyme are ATP, L-2-aminohexanedioate, L-cysteine, L-valine, and H2O, whereas its three products are AMP, diphosphate, and N-[L-5-amino-5-carboxypentanoyl]-L-cysteinyl-D-valine. ACVS is an example of a nonribosomal peptide synthetase (NRPS). It participates in penicillin and cephalosporin biosyntheses. (en) |
| dbo:ecNumber |
6.3.2.26 |
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dbr:Penicillin dbr:Valine dbc:Enzymes_of_unknown_structure dbr:Chemical_reaction dbr:Enzyme dbr:Substrate_(biochemistry) dbr:Cephalosporin dbr:Adenosine_monophosphate dbr:Adenosine_triphosphate dbr:Cysteine dbr:Nonribosomal_peptide dbr:Product_(chemistry) dbc:EC_6.3.2 dbr:Catalysis dbr:Water dbr:Diphosphate |
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57219 (xsd:integer) |
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6.300000 (xsd:double) |
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50564 (xsd:integer) |
| dbp:iubmbEcNumber |
6 (xsd:integer) |
| dbp:name |
N--(L)-cysteinyl-(D)-valine synthase (en) |
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dbc:Enzymes_of_unknown_structure dbc:EC_6.3.2 |
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owl:Thing dbo:Biomolecule wikidata:Q206229 wikidata:Q8047 yago:Abstraction100002137 yago:Activator114723079 yago:Catalyst114723628 yago:Chemical114806838 yago:Compound114818238 yago:Enzyme114732946 yago:Macromolecule114944888 yago:Material114580897 yago:Matter100020827 yago:Molecule114682133 yago:OrganicCompound114727670 yago:Part113809207 yago:PhysicalEntity100001930 yago:Protein114728724 yago:Relation100031921 dbo:Enzyme yago:Substance100019613 yago:Thing100002452 yago:Unit109465459 yago:WikicatEnzymesOfUnknownStructure |
| rdfs:comment |
ACV synthetase (ACVS, L-δ-(α-aminoadipoyl)-L-cysteinyl-D-valine synthetase, N-(5-amino-5-carboxypentanoyl)-L-cysteinyl-D-valine synthase, EC 6.3.2.26) is an enzyme that catalyzes the chemical reaction 3 ATP + L-2-aminohexanedioate + L-cysteine + L-valine + H2O 3 AMP + 3 PPi + N-[L-5-amino-5-carboxypentanoyl]-L-cysteinyl-D-valine The five substrates of this enzyme are ATP, L-2-aminohexanedioate, L-cysteine, L-valine, and H2O, whereas its three products are AMP, diphosphate, and N-[L-5-amino-5-carboxypentanoyl]-L-cysteinyl-D-valine. (en) |
| rdfs:label |
ACV synthetase (en) |
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freebase:ACV synthetase yago-res:ACV synthetase wikidata:ACV synthetase dbpedia-sh:ACV synthetase dbpedia-sr:ACV synthetase https://global.dbpedia.org/id/4KTFU |
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wikipedia-en:ACV_synthetase?oldid=1096890271&ns=0 |
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N-(5-Amino-5-carboxypentanoyl)-(L)-cysteinyl-(D)-valine synthase (en) |
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dbr:L-2-aminohexanedioate:L-cysteine:L-valine_ligase_(AMP-forming,_valine-inverting) dbr:N-(5-amino-5-carboxypentanoyl)-L-cysteinyl-D-valine_synthase dbr:EC_6.3.2.26 |
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dbr:Beta-lactam_antibiotics dbr:Thienamycin dbr:L-2-aminohexanedioate:L-cysteine:L-valine_ligase_(AMP-forming,_valine-inverting) dbr:N-(5-amino-5-carboxypentanoyl)-L-cysteinyl-D-valine_synthase dbr:EC_6.3.2.26 |
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wikipedia-en:ACV_synthetase |