AK3L1 (original) (raw)
Adenylate kinase isoenzyme 4, mitochondrial is an enzyme that in humans is encoded by the AK4 gene. This gene encodes a member of the adenylate kinase family of enzymes. The encoded protein is localized to the mitochondrial matrix. Adenylate kinases regulate the adenine and guanine nucleotide compositions within a cell by catalyzing the reversible transfer of phosphate group among these nucleotides. Five isozymes of adenylate kinase have been identified in vertebrates. Expression of these isozymes is tissue-specific and developmentally regulated. A pseudogene for this gene has been located on chromosome 17. Three transcript variants encoding the same protein have been identified for this gene. Sequence alignment suggests that the gene defined by NM_013410, NM_203464, and NM_001005353 is lo
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| dbo:abstract | Adenylate kinase isoenzyme 4, mitochondrial is an enzyme that in humans is encoded by the AK4 gene. This gene encodes a member of the adenylate kinase family of enzymes. The encoded protein is localized to the mitochondrial matrix. Adenylate kinases regulate the adenine and guanine nucleotide compositions within a cell by catalyzing the reversible transfer of phosphate group among these nucleotides. Five isozymes of adenylate kinase have been identified in vertebrates. Expression of these isozymes is tissue-specific and developmentally regulated. A pseudogene for this gene has been located on chromosome 17. Three transcript variants encoding the same protein have been identified for this gene. Sequence alignment suggests that the gene defined by NM_013410, NM_203464, and NM_001005353 is located on chromosome 1. Expression of AK4 may regulate global cellular ATP levels and modulate the AMPK signaling pathway. (en) AK4 (англ. Adenylate kinase 4) – білок, який кодується однойменним геном, розташованим у людей на короткому плечі 1-ї хромосоми. Довжина поліпептидного ланцюга білка становить 223 амінокислот, а молекулярна маса — 25 268. Послідовність амінокислот A: АланінC: ЦистеїнD: Аспарагінова кислотаE: Глутамінова кислотаF: ФенілаланінG: ГліцинH: ГістидинI: ІзолейцинK: ЛізинL: ЛейцинM: МетіонінN: АспарагінP: ПролінQ: ГлутамінR: АргінінS: СеринT: ТреонінV: ВалінW: Триптофан Y: Тирозин Кодований геном білок за функціями належить до трансфераз, кіназ. Білок має сайт для зв'язування з АТФ, нуклеотидами, ГТФ. Локалізований у мітохондрії. (uk) |
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| dbo:wikiPageWikiLink | dbr:Nucleotide dbr:Sequence_alignment dbr:Pseudogene dbr:Enzyme dbr:Gene dbr:Adenylate_kinase dbr:Adenine dbr:Chromosome_1 dbr:Chromosome_17 dbr:Isozyme dbr:Guanine dbr:Mitochondrial_matrix dbr:Phosphate dbr:Catalysis dbr:Vertebrates |
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| gold:hypernym | dbr:Enzyme |
| rdf:type | owl:Thing dbo:Biomolecule dbo:Gene wikidata:Q206229 wikidata:Q7187 dbo:HumanGene dbo:Protein |
| rdfs:comment | Adenylate kinase isoenzyme 4, mitochondrial is an enzyme that in humans is encoded by the AK4 gene. This gene encodes a member of the adenylate kinase family of enzymes. The encoded protein is localized to the mitochondrial matrix. Adenylate kinases regulate the adenine and guanine nucleotide compositions within a cell by catalyzing the reversible transfer of phosphate group among these nucleotides. Five isozymes of adenylate kinase have been identified in vertebrates. Expression of these isozymes is tissue-specific and developmentally regulated. A pseudogene for this gene has been located on chromosome 17. Three transcript variants encoding the same protein have been identified for this gene. Sequence alignment suggests that the gene defined by NM_013410, NM_203464, and NM_001005353 is lo (en) AK4 (англ. Adenylate kinase 4) – білок, який кодується однойменним геном, розташованим у людей на короткому плечі 1-ї хромосоми. Довжина поліпептидного ланцюга білка становить 223 амінокислот, а молекулярна маса — 25 268. Послідовність амінокислот A: АланінC: ЦистеїнD: Аспарагінова кислотаE: Глутамінова кислотаF: ФенілаланінG: ГліцинH: ГістидинI: ІзолейцинK: ЛізинL: ЛейцинM: МетіонінN: АспарагінP: ПролінQ: ГлутамінR: АргінінS: СеринT: ТреонінV: ВалінW: Триптофан Y: Тирозин (uk) |
| rdfs:label | AK3L1 (en) AK4 (ген) (uk) |
| owl:sameAs | freebase:AK3L1 wikidata:AK3L1 dbpedia-uk:AK3L1 https://global.dbpedia.org/id/izUu |
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