| dbo:abstract |
AM-919 (part of the AM cannabinoid series) is an analgesic drug which is a cannabinoid receptor agonist. It is a derivative of HU-210 which has been substituted with a 6β-(3-hydroxypropyl) group. This adds a "southern" aliphatic hydroxyl group to the molecule as seen in the CP-series of nonclassical cannabinoid drugs, and so AM-919 represents a hybrid structure between the classical dibenzopyran and nonclassical cannabinoid families. AM-919 is somewhat less potent than HU-210 itself, but is still a potent agonist at both CB1 and CB2 with moderate selectivity for CB1, with a Ki of 2.2 nM at CB1 and 3.4 nM at CB2. (en) |
| dbo:casNumber |
164228-46-0 |
| dbo:chEMBL |
121118 |
| dbo:fdaUniiCode |
52KD6XK4KF |
| dbo:pubchem |
10741414 |
| dbo:thumbnail |
wiki-commons:Special:FilePath/AM-919_Structure.svg?width=300 |
| dbo:wikiPageID |
17361070 (xsd:integer) |
| dbo:wikiPageLength |
3467 (xsd:nonNegativeInteger) |
| dbo:wikiPageRevisionID |
1099629770 (xsd:integer) |
| dbo:wikiPageWikiLink |
dbc:Benzochromenes dbc:Phenols dbc:Primary_alcohols dbr:Dissociation_constant dbr:List_of_AM_cannabinoids dbr:AM-4030 dbr:Aliphatic dbr:Analgesic dbr:HU-210 dbc:AM_cannabinoids dbr:Cannabinoid dbr:Hydroxyl dbr:Cannabinoid_receptor_1 dbr:Cannabinoid_receptor_2 dbr:Cannabinoid_receptor_agonist dbr:CP_cannabinoids dbr:Dibenzopyran |
| dbp:c |
27 (xsd:integer) |
| dbp:casNumber |
164228 (xsd:integer) |
| dbp:chembl |
121118 (xsd:integer) |
| dbp:chemspiderid |
8916745 (xsd:integer) |
| dbp:h |
44 (xsd:integer) |
| dbp:iupacName |
-9 (xsd:integer) |
| dbp:o |
4 (xsd:integer) |
| dbp:pubchem |
10741414 (xsd:integer) |
| dbp:smiles |
OCCCC3C1CCCCC1c2cccCCCCCCC (en) |
| dbp:stdinchi |
1 (xsd:integer) |
| dbp:stdinchikey |
PHILDZBONNKMNU-UOTIDGTBSA-N (en) |
| dbp:unii |
52 (xsd:integer) |
| dbp:verifiedrevid |
477236033 (xsd:integer) |
| dbp:watchedfields |
changed (en) |
| dbp:width |
240 (xsd:integer) |
| dbp:wikiPageUsesTemplate |
dbt:Cannabinoid-stub dbt:Cannabinoids dbt:Drugbox dbt:Reflist dbt:Short_description dbt:Cascite dbt:Chemspidercite dbt:Ebicite dbt:Fdacite dbt:Stdinchicite |
| dcterms:subject |
dbc:Benzochromenes dbc:Phenols dbc:Primary_alcohols dbc:AM_cannabinoids |
| gold:hypernym |
dbr:Drug |
| rdf:type |
owl:Thing dul:ChemicalObject dbo:ChemicalSubstance wikidata:Q8386 yago:Abstraction100002137 yago:Agent114778436 yago:Alcohol107884567 yago:Beverage107881800 yago:CausalAgent100007347 yago:Chemical114806838 yago:Compound114818238 yago:Drug103247620 yago:DrugOfAbuse103248958 yago:Fluid114939900 yago:Food100021265 yago:Liquid114940386 yago:Material114580897 yago:Matter100020827 yago:OrganicCompound114727670 yago:Part113809207 yago:Phenol114989545 yago:PhysicalEntity100001930 yago:Relation100031921 dbo:Drug yago:Substance100019613 yago:Substance100020090 yago:WikicatAlcohols yago:WikicatPhenols umbel-rc:DrugProduct |
| rdfs:comment |
AM-919 (part of the AM cannabinoid series) is an analgesic drug which is a cannabinoid receptor agonist. It is a derivative of HU-210 which has been substituted with a 6β-(3-hydroxypropyl) group. This adds a "southern" aliphatic hydroxyl group to the molecule as seen in the CP-series of nonclassical cannabinoid drugs, and so AM-919 represents a hybrid structure between the classical dibenzopyran and nonclassical cannabinoid families. (en) |
| rdfs:label |
AM-919 (en) |
| owl:sameAs |
freebase:AM-919 yago-res:AM-919 wikidata:AM-919 dbpedia-sh:AM-919 dbpedia-sr:AM-919 https://global.dbpedia.org/id/4JqLS |
| prov:wasDerivedFrom |
wikipedia-en:AM-919?oldid=1099629770&ns=0 |
| foaf:depiction |
wiki-commons:Special:FilePath/AM-919_Structure.svg |
| foaf:isPrimaryTopicOf |
wikipedia-en:AM-919 |
| is dbo:wikiPageRedirects of |
dbr:C27H44O4 |
| is dbo:wikiPageWikiLink of |
dbr:List_of_psychedelic_drugs dbr:C27H44O4 dbr:List_of_AM_cannabinoids dbr:AM-4030 dbr:AM-938 |
| is foaf:primaryTopic of |
wikipedia-en:AM-919 |
