| dbo:abstract |
Abaloparatide, sold under the brand name Tymlos among others, is a parathyroid hormone-related protein (PTHrP) analog medication used to treat osteoporosis. It is an anabolic (i.e., bone growing) agent. In 2017, it was approved to treat postmenopausal osteoporosis in the United States. (en) Abaloparatyd (łac. abaloparatidum) – wielofunkcyjny organiczny związek chemiczny, rekombinowany ludzki peptyd podobny do parathormonu, agonista receptora PTH1, stosowany w leczeniu osteoporozy. (pl) BA058是一种用于治疗骨质疏松症的模拟药物。根据Radius公司所作的2期试验，该药物可以在半年内提升患者易骨折处的骨矿物质密度，耐受性、安全性的实验结果均受到肯定。目前正展开3期试验，包含了皮下注射形式的试验。 (zh) |
| dbo:alternativeName |
Tymlos (en) |
| dbo:casNumber |
247062-33-5 |
| dbo:chEMBL |
3301581 |
| dbo:drugbank |
DB05084 |
| dbo:fdaUniiCode |
AVK0I6HY2U |
| dbo:kegg |
D10885 |
| dbo:medlinePlus |
a617038 |
| dbo:pubchem |
76943386 |
| dbo:wikiPageExternalLink |
https://druginfo.nlm.nih.gov/drugportal/name/abaloparatide |
| dbo:wikiPageID |
33852023 (xsd:integer) |
| dbo:wikiPageLength |
21230 (xsd:nonNegativeInteger) |
| dbo:wikiPageRevisionID |
1116139435 (xsd:integer) |
| dbo:wikiPageWikiLink |
dbr:G_protein–coupled_receptor dbr:Subcutaneous_injection dbr:Committee_for_Medicinal_Products_for_Human_Use dbr:Transdermal_patch dbr:Anabolic dbr:European_Medicines_Agency dbr:Osteoporosis dbr:Osteosarcoma dbr:Teriparatide dbc:Osteoporosis_drugs dbc:Parathyroid_hormone_receptor_agonists dbr:Medication dbr:Parathyroid_hormone-related_protein dbr:Parathyroid_hormone_1_receptor dbr:Indicated dbr:Alendronate |
| dbp:atcPrefix |
H05 (en) |
| dbp:atcSuffix |
AA04 (en) |
| dbp:c |
174 (xsd:integer) |
| dbp:casNumber |
247062 (xsd:integer) |
| dbp:chembl |
3301581 (xsd:integer) |
| dbp:chemspiderid |
34443170 (xsd:integer) |
| dbp:dailymedid |
Abaloparatide (en) |
| dbp:drugbank |
DB05084 (en) |
| dbp:h |
299 (xsd:integer) |
| dbp:iupacName |
L-alanyl-L-valyl-L-seryl-L-α-glutamyl-L-histidyl-L-glutaminyl-L-leucyl-L-leucyl-L-histidyl-L-α-aspartyl-L-lysylglycyl-L-lysyl-L-seryl-L-isoleucyl-L-glutaminyl-L-α-aspartyl-L-leucyl-L-arginyl-L-arginyl-L-arginyl-L-α-glutamyl-L-leucyl-L-leucyl-L-α-glutamyl-L-lysyl-L-leucyl-L-leucyl-2-methylalanyl-L-lysyl-L-leucyl-L-histidyl-L-threonyl-L-alaninamide (en) |
| dbp:kegg |
D10885 (en) |
| dbp:legalUs |
Rx-only (en) |
| dbp:medlineplus |
a617038 (en) |
| dbp:n |
56 (xsd:integer) |
| dbp:o |
49 (xsd:integer) |
| dbp:pubchem |
76943386 (xsd:integer) |
| dbp:routesOfAdministration |
dbr:Subcutaneous_injection |
| dbp:smiles |
CC[C@H][C@@H]NC[C@H]NC[C@H]NCCNC[C@H]NC[C@H]NC[C@H]NC[C@H]NC[C@H]NC[C@H]NC[C@H]NC[C@H]NC[C@H]NC[C@H]NC[C@H]N (en) |
| dbp:stdinchi |
1 (xsd:integer) |
| dbp:stdinchikey |
BVISQZFBLRSESR-XSCWXTNMSA-N (en) |
| dbp:synonyms |
BA058, BIM-44058 (en) |
| dbp:tradename |
Tymlos (en) |
| dbp:unii |
AVK0I6HY2U (en) |
| dbp:wikiPageUsesTemplate |
dbt:COI dbt:Cite_web dbt:Infobox_drug dbt:Portal_bar dbt:Reflist dbt:Short_description dbt:Drugs.com dbt:Calcium_homeostasis |
| dct:subject |
dbc:Osteoporosis_drugs dbc:Parathyroid_hormone_receptor_agonists |
| gold:hypernym |
dbr:Drug |
| rdf:type |
owl:Thing dul:ChemicalObject dbo:ChemicalSubstance wikidata:Q8386 yago:Agent114778436 yago:CausalAgent100007347 yago:Drug103247620 yago:Matter100020827 yago:PhysicalEntity100001930 dbo:Drug yago:Substance100020090 yago:WikicatDrugsActingOnTheMusculoskeletalSystem |
| rdfs:comment |
Abaloparatide, sold under the brand name Tymlos among others, is a parathyroid hormone-related protein (PTHrP) analog medication used to treat osteoporosis. It is an anabolic (i.e., bone growing) agent. In 2017, it was approved to treat postmenopausal osteoporosis in the United States. (en) Abaloparatyd (łac. abaloparatidum) – wielofunkcyjny organiczny związek chemiczny, rekombinowany ludzki peptyd podobny do parathormonu, agonista receptora PTH1, stosowany w leczeniu osteoporozy. (pl) BA058是一种用于治疗骨质疏松症的模拟药物。根据Radius公司所作的2期试验，该药物可以在半年内提升患者易骨折处的骨矿物质密度，耐受性、安全性的实验结果均受到肯定。目前正展开3期试验，包含了皮下注射形式的试验。 (zh) |
| rdfs:label |
Abaloparatide (en) Abaloparatyd (pl) BA058 (zh) |
| owl:sameAs |
freebase:Abaloparatide yago-res:Abaloparatide wikidata:Abaloparatide http://or.dbpedia.org/resource/ଆବାଲୋପାରାଟାଇଡ dbpedia-pl:Abaloparatide dbpedia-zh:Abaloparatide https://global.dbpedia.org/id/4Uo9R |
| prov:wasDerivedFrom |
wikipedia-en:Abaloparatide?oldid=1116139435&ns=0 |
| foaf:isPrimaryTopicOf |
wikipedia-en:Abaloparatide |
| is dbo:wikiPageRedirects of |
dbr:BA058 dbr:C174H299N56O49 dbr:Eladynos dbr:Tymlos dbr:Abaloparatide_acetate |
| is dbo:wikiPageWikiLink of |
dbr:BA058 dbr:Osteopenia dbr:C174H299N56O49 dbr:ATC_code_H05 dbr:Eladynos dbr:List_of_signaling_peptide/protein_receptor_modulators dbr:Signaling_peptide_receptor dbr:Resilience_engineering dbr:Parathyroid_hormone-related_protein dbr:Tymlos dbr:Abaloparatide_acetate |
| is foaf:primaryTopic of |
wikipedia-en:Abaloparatide |