Alfred Burger (original) (raw)

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Alfred Burger (* 6. September 1905 in Wien; † 30. Dezember 2000) war ein US-amerikanischer Chemiker österreichischer Abstammung. Er war Gründer und erster Chefredakteur des Journal of Medicinal Chemistry. Burgers Arbeitsschwerpunkt ist die Medizinische Chemie, vor allem die Wirkungsweise, der chemische Aufbau und der Missbrauch von Medikamenten und Drogen.

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dbo:abstract Alfred Burger (6 September 1905 – 30 December 2000) was a prominent chemist and a pioneer in medical chemistry. Burger was born in Vienna, the capitol of the Austro-Hungarian Empire, on 6 September 1905. He was the son of S. L. Burger (a civil servant) and Clariss Burger. He received a Ph.D. degree from the University of Vienna in 1928. His dissertation was entitled, "Synthesis of Benzylisoquinoline Alkaloids." He traveled to the University of Virginia as a postdoctoral fellow synthesizing morphine analogs with minimal addictive properties. He worked as a research chemist in Switzerland before emigrating to the United States in 1929. He then became a research associate at the Drug Addiction Laboratory of the National Research Council at the University of Virginia where he conducted research on the chemistry of opium alkaloids and the synthesis of morphine substitutes. In 1938, he joined the faculty of University of Virginia where he remained until 1970. He reached the rank of full professor in 1952. His research activities with a staff of 40 graduate and 33 postdoctoral students included studies on the design and synthesis of analgesic, chemotherapeutic, and antidepressant drugs. One of his synthetic compounds was developed as a widely used clinical antidepressant under the name of tranylcypromine. In the 1950s, Burger defined the principles of medicinal chemistry when he wrote its first-ever textbook, Burger's Medicinal Chemistry and Drug Discovery, which has had at least six editions. Burger also became the first editor of the Journal of Medicinal Chemistry. He founded the Journal of Medicinal Chemistry in 1958 and served as its editor for 14 years. He also served as editor of Medicinal Chemistry Research and as Chairman of the ACS Division of Medicinal Chemistry. Burger authored over 200 papers and numerous books. His other books include Understanding Medications; Searching, Teaching & Writing-What Fun; Drugs & People; Drugs Affecting the Peripheral Nervous System; and Drugs Affecting the Central Nervous System. (en) Alfred Burger (* 6. September 1905 in Wien; † 30. Dezember 2000) war ein US-amerikanischer Chemiker österreichischer Abstammung. Er war Gründer und erster Chefredakteur des Journal of Medicinal Chemistry. Burgers Arbeitsschwerpunkt ist die Medizinische Chemie, vor allem die Wirkungsweise, der chemische Aufbau und der Missbrauch von Medikamenten und Drogen. (de)
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dbp:birthDate 1905-09-06 (xsd:date)
dbp:birthPlace dbr:Vienna dbr:Austria-Hungary
dbp:deathDate 2000-12-30 (xsd:date)
dbp:discipline dbr:Medicinal_chemistry
dbp:doctoralAdvisor Ernest Späth (en)
dbp:education Ph.D., University of Vienna, 1928 (en)
dbp:name Alfred Burger (en)
dbp:nationality dbr:United_States dbr:Austria
dbp:occupation dbr:Professor dbr:Scientist
dbp:spouse Frances Page Burger (en)
dbp:thesisTitle Synthesis of Benzoisoquinoline Alkaloids (en)
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rdfs:comment Alfred Burger (* 6. September 1905 in Wien; † 30. Dezember 2000) war ein US-amerikanischer Chemiker österreichischer Abstammung. Er war Gründer und erster Chefredakteur des Journal of Medicinal Chemistry. Burgers Arbeitsschwerpunkt ist die Medizinische Chemie, vor allem die Wirkungsweise, der chemische Aufbau und der Missbrauch von Medikamenten und Drogen. (de) Alfred Burger (6 September 1905 – 30 December 2000) was a prominent chemist and a pioneer in medical chemistry. Burger was born in Vienna, the capitol of the Austro-Hungarian Empire, on 6 September 1905. He was the son of S. L. Burger (a civil servant) and Clariss Burger. His research activities with a staff of 40 graduate and 33 postdoctoral students included studies on the design and synthesis of analgesic, chemotherapeutic, and antidepressant drugs. One of his synthetic compounds was developed as a widely used clinical antidepressant under the name of tranylcypromine. (en)
rdfs:label Alfred Burger (en) Alfred Burger (Chemiker) (de)
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