| dbo:abstract |
Aminohippuric acid or para-aminohippuric acid (PAH), a derivative of hippuric acid, is a diagnostic agent useful in medical tests involving the kidney used in the measurement of renal plasma flow. It is an amide derivative of the amino acid glycine and para-aminobenzoic acid that is not naturally found in humans; it needs to be IV infused before diagnostic use. (en) p-Aminohippursäure, auch Paraaminohippursäure oder 4-Aminohippursäure, ist eine von der Hippursäure abgeleitete chemische Verbindung. Sie findet insbesondere als Diagnostikum zur Untersuchung der Nierenfunktion Anwendung. Als Kondensationsprodukt aus p-Aminobenzoesäure und der Aminosäure Glycin kann sie im Körper des Menschen als Stoffwechselprodukt auftreten. (de) L'acide aminohippurique, ou plus précisément l'acide paraaminohippurique, parfois abrégé en PAH (de l'anglais para-aminohippuric acid) est un dérivé de l'acide hippurique, un produit utilisé pour mesurer le débit plasmatique rénal. C'est un dérivé amide de l'acide aminé glycine et de l'acide para-aminobenzoïque. (fr) Il PAI (acido para-amminoippurico) è un composto esogeno secreto a livello dei capillari peritubulari renali. L’acido para-aminoippurico consente la rilevazione della clearance di tutte quelle sostanze che subiscono soltanto il meccanismo di secrezione; il PAI infatti viene eliminato nelle urine soltanto attraverso il meccanismo della secrezione. Il valore del flusso plasmatico renale può essere ottenuto tramite il test con acido p-ammino ippurico. La clearance dell’acido para-aminoippurico è di 490-820 ml/minuto nell’uomo, di 440-745 ml/minuto nelle donne e di 34-98 ml/minuto nei neonati. L’alterazione del suo livello nelle urine indica un’alterazione della portata renale ematica. (it) |
| dbo:casNumber |
(sodium salt) 61-78-9 |
| dbo:chEBI |
104011 |
| dbo:chEMBL |
463 |
| dbo:drugbank |
DB00345 |
| dbo:fdaUniiCode |
Y79XT83BJ9 |
| dbo:kegg |
D06890 |
| dbo:pubchem |
2148 |
| dbo:thumbnail |
wiki-commons:Special:FilePath/aminohippuric_acid.png?width=300 |
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18984025 (xsd:integer) |
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4420 (xsd:nonNegativeInteger) |
| dbo:wikiPageRevisionID |
1060635638 (xsd:integer) |
| dbo:wikiPageWikiLink |
dbc:Acetic_acids dbr:Glycine dbr:Amide dbr:Amino_acid dbc:Benzamides dbr:PAH_clearance dbr:PKa dbr:Renal_plasma_flow dbc:Amino_acid_derivatives dbc:Anilines dbr:Hippuric_acid dbr:Kidney dbr:Sodium dbr:Salt_(chemistry) dbr:Ortho-iodohippurate dbr:Para-aminobenzoic_acid dbr:Renal_extraction_ratio |
| dbp:atcPrefix |
V04 (en) |
| dbp:atcSuffix |
CH30 (en) |
| dbp:c |
9 (xsd:integer) |
| dbp:casNumber |
61 (xsd:integer) |
| dbp:chebi |
104011 (xsd:integer) |
| dbp:chembl |
463 (xsd:integer) |
| dbp:chemspiderid |
2063 (xsd:integer) |
| dbp:drugName |
Aminohippurate (en) |
| dbp:drugbank |
DB00345 (en) |
| dbp:h |
10 (xsd:integer) |
| dbp:iupacName |
acetic acid (en) |
| dbp:iupharLigand |
4810 (xsd:integer) |
| dbp:kegg |
D06890 (en) |
| dbp:n |
2 (xsd:integer) |
| dbp:niaidChemdb |
19143 (xsd:integer) |
| dbp:o |
3 (xsd:integer) |
| dbp:pubchem |
2148 (xsd:integer) |
| dbp:smiles |
O=CNCCO (en) |
| dbp:stdinchi |
1 (xsd:integer) |
| dbp:stdinchikey |
HSMNQINEKMPTIC-UHFFFAOYSA-N (en) |
| dbp:synonyms |
PAH, PAHA, Aminohippurate, 4-Aminohippuric acid , N-glycine, para-Aminohippurate (en) |
| dbp:unii |
Y79XT83BJ9 (en) |
| dbp:verifiedrevid |
443661015 (xsd:integer) |
| dbp:watchedfields |
changed (en) |
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dbt:CAS dbt:Drugbox dbt:Reflist dbt:Renal_physiology dbt:Cascite dbt:Chemspidercite dbt:Drugbankcite dbt:Ebicite dbt:Fdacite dbt:Keggcite dbt:Stdinchicite dbt:Diagnostic_agents |
| dct:subject |
dbc:Acetic_acids dbc:Benzamides dbc:Amino_acid_derivatives dbc:Anilines |
| gold:hypernym |
dbr:Agent |
| rdf:type |
owl:Thing dul:ChemicalObject dbo:ChemicalSubstance wikidata:Q8386 yago:WikicatAminoAcidDerivatives yago:WikicatAnilines yago:WikicatCarboxylicAcids yago:WikicatMolecularFormulas yago:Abstraction100002137 yago:AceticAcid114599168 yago:Acid114607521 yago:AliphaticCompound114601294 yago:Amine114739004 yago:Aniline114754505 yago:Calculation105802185 yago:CarboxylicAcid114739360 yago:Chemical114806838 yago:Cognition100023271 yago:Communication100033020 yago:Compound114818238 yago:DerivedFunction106014730 yago:Formula106816935 yago:HigherCognitiveProcess105770664 yago:Material114580897 yago:Matter100020827 yago:Message106598915 yago:MethaneSeries114951377 yago:MolecularFormula106817173 yago:OrganicCompound114727670 yago:Part113809207 yago:PhysicalEntity100001930 yago:ProblemSolving105796750 yago:Process105701363 yago:PsychologicalFeature100023100 yago:Relation100031921 dbo:Drug yago:Statement106722453 yago:Substance100019613 yago:Thinking105770926 yago:WikicatAceticAcids umbel-rc:DrugProduct |
| rdfs:comment |
Aminohippuric acid or para-aminohippuric acid (PAH), a derivative of hippuric acid, is a diagnostic agent useful in medical tests involving the kidney used in the measurement of renal plasma flow. It is an amide derivative of the amino acid glycine and para-aminobenzoic acid that is not naturally found in humans; it needs to be IV infused before diagnostic use. (en) p-Aminohippursäure, auch Paraaminohippursäure oder 4-Aminohippursäure, ist eine von der Hippursäure abgeleitete chemische Verbindung. Sie findet insbesondere als Diagnostikum zur Untersuchung der Nierenfunktion Anwendung. Als Kondensationsprodukt aus p-Aminobenzoesäure und der Aminosäure Glycin kann sie im Körper des Menschen als Stoffwechselprodukt auftreten. (de) L'acide aminohippurique, ou plus précisément l'acide paraaminohippurique, parfois abrégé en PAH (de l'anglais para-aminohippuric acid) est un dérivé de l'acide hippurique, un produit utilisé pour mesurer le débit plasmatique rénal. C'est un dérivé amide de l'acide aminé glycine et de l'acide para-aminobenzoïque. (fr) Il PAI (acido para-amminoippurico) è un composto esogeno secreto a livello dei capillari peritubulari renali. L’acido para-aminoippurico consente la rilevazione della clearance di tutte quelle sostanze che subiscono soltanto il meccanismo di secrezione; il PAI infatti viene eliminato nelle urine soltanto attraverso il meccanismo della secrezione. Il valore del flusso plasmatico renale può essere ottenuto tramite il test con acido p-ammino ippurico. La clearance dell’acido para-aminoippurico è di 490-820 ml/minuto nell’uomo, di 440-745 ml/minuto nelle donne e di 34-98 ml/minuto nei neonati. (it) |
| rdfs:label |
P-Aminohippursäure (de) Aminohippuric acid (en) Acido p-amminoippurico (it) Acide aminohippurique (fr) |
| owl:sameAs |
freebase:Aminohippuric acid yago-res:Aminohippuric acid http://www4.wiwiss.fu-berlin.de/sider/resource/drugs/2148 wikidata:Aminohippuric acid dbpedia-de:Aminohippuric acid dbpedia-fa:Aminohippuric acid dbpedia-fr:Aminohippuric acid dbpedia-it:Aminohippuric acid dbpedia-sh:Aminohippuric acid dbpedia-sr:Aminohippuric acid dbpedia-vi:Aminohippuric acid https://global.dbpedia.org/id/2hded |
| prov:wasDerivedFrom |
wikipedia-en:Aminohippuric_acid?oldid=1060635638&ns=0 |
| foaf:depiction |
wiki-commons:Special:FilePath/aminohippuric_acid.png |
| foaf:isPrimaryTopicOf |
wikipedia-en:Aminohippuric_acid |
| foaf:name |
Aminohippurate (en) |
| is dbo:wikiPageRedirects of |
dbr:PAHA dbr:C9H10N2O3 dbr:ATC_code_V04CH30 dbr:ATCvet_code_QV04CH30 dbr:Aminohippurate_sodium dbr:Aminohippuric_acids dbr:P-aminohippuric_acid dbr:Para-Aminohippurate dbr:Para-Aminohippuric_acid dbr:Para-aminohippurate dbr:Para-aminohippuric_acid dbr:Para_aminohippurate dbr:Para_aminohippuric_acid dbr:4-Aminohippuric_acid |
| is dbo:wikiPageWikiLink of |
dbr:Benzamide dbr:Organic_anion dbr:PAHA dbr:C9H10N2O3 dbr:ATC_code_V04CH30 dbr:ATCvet_code_QV04CH30 dbr:Hippuric_acid dbr:ATC_code_V04 dbr:Aminohippurate_sodium dbr:Aminohippuric_acids dbr:P-aminohippuric_acid dbr:Para-Aminohippurate dbr:Para-Aminohippuric_acid dbr:Para-aminohippurate dbr:Para-aminohippuric_acid dbr:Para_aminohippurate dbr:Para_aminohippuric_acid dbr:4-Aminohippuric_acid |
| is foaf:primaryTopic of |
wikipedia-en:Aminohippuric_acid |
