dbo:abstract |
Androsterone glucuronide (ADT-G) is a major circulating and urinary metabolite of testosterone and dihydrotestosterone (DHT). It accounts for 93% of total androgen glucuronides in women. ADT-G is formed from androsterone by UDP-glucuronosyltransferases, with the major enzymes being UGT2B15 and UGT2B17. It is a marker of acne in women while androstanediol glucuronide is a marker of hirsutism (excess hair growth) in women. (en) |
dbo:alternativeName |
ADT-G; 5α-Androstan-3α-ol-17-one 3-glucuronide (en) |
dbo:iupacName |
17-Oxo-5α-androstan-3α-yl β-(D)-glucopyranosiduronic acid (en) (2S,3S,4S,5R,6R)-6-{[(3aS,3bR,5aS,7R,9aS,9bS,11aS)-9a,11a-Dimethyl-1-oxohexadecahydro-1H-cyclopenta[a]pheananthren-7-yl]oxy}-3,4,5-trihydroxyoxane-2-carboxylic acid (en) |
dbo:thumbnail |
wiki-commons:Special:FilePath/Androsterone_glucuronide.svg?width=300 |
dbo:wikiPageExternalLink |
http://www.hmdb.ca/metabolites/HMDB02829 |
dbo:wikiPageID |
52492284 (xsd:integer) |
dbo:wikiPageLength |
2908 (xsd:nonNegativeInteger) |
dbo:wikiPageRevisionID |
1055133021 (xsd:integer) |
dbo:wikiPageWikiLink |
dbr:Metabolite dbc:Glucuronide_esters dbr:UGT2B15 dbc:5α-Reduced_steroid_metabolites dbc:Androstanes dbc:Human_metabolites dbr:Circulatory_system dbr:Enzyme dbr:Androstanediol_glucuronide dbr:Androsterone dbr:Androsterone_sulfate dbr:UGT2B17 dbr:3α-Androstanediol dbr:Etiocholanolone_glucuronide dbr:Hirsutism dbr:Testosterone dbr:Acne dbr:Dihydrotestosterone dbr:Urine dbr:UDP-glucuronosyltransferase |
dbp:imagefile |
Androsterone glucuronide.svg (en) |
dbp:imagesize |
250 (xsd:integer) |
dbp:iupacname |
17 (xsd:integer) |
dbp:othernames |
ADT-G; 5α-Androstan-3α-ol-17-one 3-glucuronide (en) |
dbp:pin |
-6 (xsd:integer) |
dbp:wikiPageUsesTemplate |
dbt:Biochemistry-stub dbt:Chembox dbt:Chembox_Hazards dbt:Chembox_Identifiers dbt:Chembox_Properties dbt:Reflist dbt:Steroid-stub dbt:Steroid_hormones dbt:Cascite dbt:Fdacite |
dcterms:subject |
dbc:Glucuronide_esters dbc:5α-Reduced_steroid_metabolites dbc:Androstanes dbc:Human_metabolites |
rdf:type |
owl:Thing dul:ChemicalObject dbo:ChemicalSubstance wikidata:Q11173 dbo:ChemicalCompound |
rdfs:comment |
Androsterone glucuronide (ADT-G) is a major circulating and urinary metabolite of testosterone and dihydrotestosterone (DHT). It accounts for 93% of total androgen glucuronides in women. ADT-G is formed from androsterone by UDP-glucuronosyltransferases, with the major enzymes being UGT2B15 and UGT2B17. It is a marker of acne in women while androstanediol glucuronide is a marker of hirsutism (excess hair growth) in women. (en) |
rdfs:label |
Androsterone glucuronide (en) |
owl:sameAs |
yago-res:Androsterone glucuronide wikidata:Androsterone glucuronide https://global.dbpedia.org/id/2XqQd |
prov:wasDerivedFrom |
wikipedia-en:Androsterone_glucuronide?oldid=1055133021&ns=0 |
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wiki-commons:Special:FilePath/Androsterone_glucuronide.svg |
foaf:isPrimaryTopicOf |
wikipedia-en:Androsterone_glucuronide |
is dbo:wikiPageWikiLink of |
dbr:Androgen_conjugate dbr:Pharmacokinetics_of_testosterone dbr:C25H38O8 dbr:Androstanediol_glucuronide dbr:Androsterone dbr:Androsterone_sulfate dbr:Etiocholanolone_glucuronide dbr:Testosterone_glucuronide dbr:Testosterone_sulfate |
is foaf:primaryTopic of |
wikipedia-en:Androsterone_glucuronide |