Antimotility agent (original) (raw)
Antimotility agents are drugs used to alleviate the symptoms of diarrhea. These include loperamide (Imodium), diphenoxylate with atropine (Lomotil), and opiates such as paregoric, tincture of opium, codeine, and morphine. In diarrhea caused by invasive pathogens such as Salmonella, Shigella, and Campylobacter, the use of such agents has generally been strongly discouraged, though evidence is lacking that they are harmful when administered in combination with antibiotics in Clostridium difficile cases. Use of antimotility agents in children and the elderly has also been discouraged in treatment of EHEC (Shiga-like toxin producing Escherichia coli) due to an increased rate of hemolytic uremic syndrome.
| Property | Value |
|---|---|
| dbo:abstract | Antimotility agents are drugs used to alleviate the symptoms of diarrhea. These include loperamide (Imodium), diphenoxylate with atropine (Lomotil), and opiates such as paregoric, tincture of opium, codeine, and morphine. In diarrhea caused by invasive pathogens such as Salmonella, Shigella, and Campylobacter, the use of such agents has generally been strongly discouraged, though evidence is lacking that they are harmful when administered in combination with antibiotics in Clostridium difficile cases. Use of antimotility agents in children and the elderly has also been discouraged in treatment of EHEC (Shiga-like toxin producing Escherichia coli) due to an increased rate of hemolytic uremic syndrome. (en) |
| dbo:wikiPageID | 31963946 (xsd:integer) |
| dbo:wikiPageLength | 1838 (xsd:nonNegativeInteger) |
| dbo:wikiPageRevisionID | 1081979334 (xsd:integer) |
| dbo:wikiPageWikiLink | dbr:Opiate dbr:Codeine dbr:Morphine dbr:Loperamide dbr:Clostridium_difficile_colitis dbr:Traveler's_diarrhea dbr:Escherichia_coli dbr:Infectious_diarrhea dbr:Shiga-like_toxin dbr:Atropine dbc:Antidiarrhoeals dbr:Salmonella dbr:Diphenoxylate dbr:Campylobacter dbr:Shigatoxigenic_and_verotoxigenic_Escherichia_coli dbr:Shigella dbr:Paregoric dbr:Hemolytic_uremic_syndrome dbr:Tincture_of_opium |
| dbp:wikiPageUsesTemplate | dbt:Gastrointestinal-drug-stub dbt:Reflist dbt:Short_description |
| dcterms:subject | dbc:Antidiarrhoeals |
| gold:hypernym | dbr:Drugs |
| rdf:type | dbo:Drug |
| rdfs:comment | Antimotility agents are drugs used to alleviate the symptoms of diarrhea. These include loperamide (Imodium), diphenoxylate with atropine (Lomotil), and opiates such as paregoric, tincture of opium, codeine, and morphine. In diarrhea caused by invasive pathogens such as Salmonella, Shigella, and Campylobacter, the use of such agents has generally been strongly discouraged, though evidence is lacking that they are harmful when administered in combination with antibiotics in Clostridium difficile cases. Use of antimotility agents in children and the elderly has also been discouraged in treatment of EHEC (Shiga-like toxin producing Escherichia coli) due to an increased rate of hemolytic uremic syndrome. (en) |
| rdfs:label | Antimotility agent (en) |
| owl:sameAs | freebase:Antimotility agent wikidata:Antimotility agent https://global.dbpedia.org/id/4R1Xc |
| prov:wasDerivedFrom | wikipedia-en:Antimotility_agent?oldid=1081979334&ns=0 |
| foaf:isPrimaryTopicOf | wikipedia-en:Antimotility_agent |
| is dbo:wikiPageWikiLink of | dbr:Cryptosporidiosis dbr:Oxyphencyclimine dbr:Shigatoxigenic_and_verotoxigenic_Escherichia_coli |
| is foaf:primaryTopic of | wikipedia-en:Antimotility_agent |