Arachidonic acid 5-hydroperoxide (original) (raw)
Arachidonic acid 5-hydroperoxide (5-hydroperoxyeicosatetraenoic acid, 5-HPETE) is an intermediate in the metabolism of arachidonic acid by the ALOX5 enzyme in humans or Alox5 enzyme in other mammals. The intermediate is then further metabolized to: a) leukotriene A4 which is then metabolized to the chemotactic factor for leukocytes, leukotriene B4, or to contractors of lung airways, leukotriene C4, leukotriene D4, and leukotriene E4; b) the leukocyte chemotactic factors, 5-Hydroxyicosatetraenoic acid and 5-oxo-eicosatetraenoic acid; or c) the specialized pro-resolving mediators of inflammation, lipoxin A4 and lipoxin B4.
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| dbo:abstract | Arachidonic acid 5-hydroperoxide (5-hydroperoxyeicosatetraenoic acid, 5-HPETE) is an intermediate in the metabolism of arachidonic acid by the ALOX5 enzyme in humans or Alox5 enzyme in other mammals. The intermediate is then further metabolized to: a) leukotriene A4 which is then metabolized to the chemotactic factor for leukocytes, leukotriene B4, or to contractors of lung airways, leukotriene C4, leukotriene D4, and leukotriene E4; b) the leukocyte chemotactic factors, 5-Hydroxyicosatetraenoic acid and 5-oxo-eicosatetraenoic acid; or c) the specialized pro-resolving mediators of inflammation, lipoxin A4 and lipoxin B4. (en) L'acide 5-hydroxyperoxyeicosatétraénoïque (5-HPETE) est un intermédiaire de la biosynthèse du leucotriène A4 à partir de l'acide arachidonique. Il est produit par l'. (fr) 5-Гидропероксиэйкозатетраеновая кислота (5-гидропероксид арахидоновой кислоты; англ. 5-hydroperoxyeicosatetraenoic acid, 5-HPETE; arachidonic acid 5-hydroperoxide) — производное арахидоновой кислоты, промежуточное соединение синтеза лейкотриенов (лейкотриена A4 как первого продукта цепи реакций). Образуется в клетках ферментом в результате реакции диоксигенации (присоединения двух атомов кислорода на месте двойной связи). (ru) 5-羟过氧化二十碳四烯酸 (英語：5-hydroperoxyeicosatetraenoic acid，5-HPETE)是体内白三烯生物合成过程中，花生四烯酸到白三烯A4的中间物质，由合成。 (zh) |
| dbo:iupacName | (5S,6E,8Z,11Z,14Z)-5-Hydroperoxyicosa-6,8,11,14-tetraenoic acid (en) |
| dbo:thumbnail | wiki-commons:Special:FilePath/5-Hydroperoxyeicosatetraenoic_acid.svg?width=300 |
| dbo:wikiPageID | 10996073 (xsd:integer) |
| dbo:wikiPageLength | 2941 (xsd:nonNegativeInteger) |
| dbo:wikiPageRevisionID | 1019657766 (xsd:integer) |
| dbo:wikiPageWikiLink | dbr:5-oxo-eicosatetraenoic_acid dbc:Eicosanoids dbc:Fatty_acids dbc:Organic_peroxides dbr:Arachidonic_acid dbr:Alox5 dbr:Leukotriene_A4 dbr:Leukotriene_B4 dbr:Leukotriene_C4 dbr:Leukotriene_D4 dbr:Leukotriene_E4 dbr:Lipoxin dbr:5-Hydroxyicosatetraenoic_acid dbc:Biochemistry dbr:Specialized_pro-resolving_mediators dbr:Chemotactic_factor dbr:ALOX5 dbr:File:Eicosanoid_synthesis.svg |
| dbp:imagefile | 5 (xsd:integer) |
| dbp:pin | -5 (xsd:integer) |
| dbp:verifiedrevid | 452418850 (xsd:integer) |
| dbp:wikiPageUsesTemplate | dbt:Eicosanoids dbt:Alkene-stub dbt:Biochem-stub dbt:Chembox dbt:Chembox_Hazards dbt:Chembox_Identifiers dbt:Chembox_Properties dbt:Leukotrienergics dbt:Reflist dbt:Cascite dbt:Chemspidercite dbt:Stdinchicite |
| dct:subject | dbc:Eicosanoids dbc:Fatty_acids dbc:Organic_peroxides dbc:Biochemistry |
| rdf:type | owl:Thing dul:ChemicalObject dbo:ChemicalSubstance wikidata:Q11173 yago:Abstraction100002137 yago:Acid114607521 yago:CarboxylicAcid114739360 yago:Chemical114806838 yago:Compound114818238 yago:FattyAcid114740227 yago:Material114580897 yago:Matter100020827 yago:Part113809207 yago:PhysicalEntity100001930 yago:Relation100031921 dbo:ChemicalCompound yago:Substance100019613 yago:WikicatFattyAcids umbel-rc:ChemicalSubstanceType |
| rdfs:comment | Arachidonic acid 5-hydroperoxide (5-hydroperoxyeicosatetraenoic acid, 5-HPETE) is an intermediate in the metabolism of arachidonic acid by the ALOX5 enzyme in humans or Alox5 enzyme in other mammals. The intermediate is then further metabolized to: a) leukotriene A4 which is then metabolized to the chemotactic factor for leukocytes, leukotriene B4, or to contractors of lung airways, leukotriene C4, leukotriene D4, and leukotriene E4; b) the leukocyte chemotactic factors, 5-Hydroxyicosatetraenoic acid and 5-oxo-eicosatetraenoic acid; or c) the specialized pro-resolving mediators of inflammation, lipoxin A4 and lipoxin B4. (en) L'acide 5-hydroxyperoxyeicosatétraénoïque (5-HPETE) est un intermédiaire de la biosynthèse du leucotriène A4 à partir de l'acide arachidonique. Il est produit par l'. (fr) 5-Гидропероксиэйкозатетраеновая кислота (5-гидропероксид арахидоновой кислоты; англ. 5-hydroperoxyeicosatetraenoic acid, 5-HPETE; arachidonic acid 5-hydroperoxide) — производное арахидоновой кислоты, промежуточное соединение синтеза лейкотриенов (лейкотриена A4 как первого продукта цепи реакций). Образуется в клетках ферментом в результате реакции диоксигенации (присоединения двух атомов кислорода на месте двойной связи). (ru) 5-羟过氧化二十碳四烯酸 (英語：5-hydroperoxyeicosatetraenoic acid，5-HPETE)是体内白三烯生物合成过程中，花生四烯酸到白三烯A4的中间物质，由合成。 (zh) |
| rdfs:label | Arachidonic acid 5-hydroperoxide (en) Acide 5-hydroxyperoxyeicosatétraénoïque (fr) 5-Гидропероксиэйкозатетраеновая кислота (ru) 5-羟过氧化二十碳四烯酸 (zh) |
| owl:sameAs | freebase:Arachidonic acid 5-hydroperoxide yago-res:Arachidonic acid 5-hydroperoxide wikidata:Arachidonic acid 5-hydroperoxide http://azb.dbpedia.org/resource/۵-هیدروپراوکسید_آراشیدونیک_اسید dbpedia-fa:Arachidonic acid 5-hydroperoxide dbpedia-fr:Arachidonic acid 5-hydroperoxide dbpedia-ru:Arachidonic acid 5-hydroperoxide dbpedia-sh:Arachidonic acid 5-hydroperoxide dbpedia-sr:Arachidonic acid 5-hydroperoxide dbpedia-zh:Arachidonic acid 5-hydroperoxide https://global.dbpedia.org/id/2d25t |
| prov:wasDerivedFrom | wikipedia-en:Arachidonic_acid_5-hydroperoxide?oldid=1019657766&ns=0 |
| foaf:depiction | wiki-commons:Special:FilePath/Eicosanoid_synthesis.svg wiki-commons:Special:FilePath/5-Hydroperoxyeicosatetraenoic_acid.svg |
| foaf:isPrimaryTopicOf | wikipedia-en:Arachidonic_acid_5-hydroperoxide |
| is dbo:wikiPageRedirects of | dbr:5-HPETE dbr:5-hydroperoxyeicosatetraenoic_acid |
| is dbo:wikiPageWikiLink of | dbr:List_of_medical_abbreviations:_H dbr:5-Hydroxyeicosatetraenoic_acid dbr:C20H32O4 dbr:5-HPETE dbr:5-hydroperoxyeicosatetraenoic_acid |
| is foaf:primaryTopic of | wikipedia-en:Arachidonic_acid_5-hydroperoxide |
