Ariadne (psychedelic) (original) (raw)
4-メチル-2,5-ジメトキシ-α-エチルフェネチルアミン(4-methyl-2,5-dimethoxy-alpha-ethylphenethylamine)は、幻覚剤の一つ。アリアドネ(ariadne)、ジモキサミン(dimoxamine)またはα-Et-DOMとも呼ばれる。との類縁体である。アレクサンダー・シュルギンにより初めて合成された。シュルギンの著書PiHKALでは、32 mgの服用で幻覚作用を引き起こすと報告している。この物質のヒトに対する薬理学特性、代謝および毒性のデータはシュルギンによるもののみである。
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dbo:abstract | Ariadne (also known as 4C-D, 4C-DOM, α-Et-2C-D, BL-3912, or dimoxamine) is a lesser-known psychedelic drug. It is a homologue of 2C-D and DOM. Ariadne was first synthesized by Alexander Shulgin. In his book PiHKAL, Shulgin reported testing Ariadne up to a dose of 32 mg, and reported that it produces psychedelia at a bare threshold. Very little data exists about the pharmacological properties, metabolism, and toxicity of Ariadne in humans apart from Shulgin's limited testing. Shulgin reported that the drug was tested by Bristol Laboratories as an antidepressant, in an anecdote where he was explaining how human testing is invaluable (compared to animal testing) on drugs that change the state of the mind. He said, "Before they launched into a full multi-clinic study to determine if it's going to be worth the animal studies or not, every person on the board of directors took it." In an animal study, Ariadne was shown to produce stimulus generalization in rats trained to respond to the drug MDMA. (en) 4-メチル-2,5-ジメトキシ-α-エチルフェネチルアミン(4-methyl-2,5-dimethoxy-alpha-ethylphenethylamine)は、幻覚剤の一つ。アリアドネ(ariadne)、ジモキサミン(dimoxamine)またはα-Et-DOMとも呼ばれる。との類縁体である。アレクサンダー・シュルギンにより初めて合成された。シュルギンの著書PiHKALでは、32 mgの服用で幻覚作用を引き起こすと報告している。この物質のヒトに対する薬理学特性、代謝および毒性のデータはシュルギンによるもののみである。 (ja) Dimoksamina, ariadna – organiczny związek chemiczny z grupy psychodelicznych fenyloetyloamin, homolog 2C-D i DOM. Zsyntezowana po raz pierwszy przez Alexandra Shulgina, opisana w PiHKAL z dawkowaniem do 32 mg oraz nieokreślonym czasem trwania efektów. (pl) Ariadne (também conhecido como 4C-D, 4C-DOM, α-Et-2C-D, BL-3912 ou dimoxamina) é uma droga psicodélica pouco conhecida. É um homólogo do 2C-D e dimetoxianfetamina (DOM). Ariadne foi sintetizado pela primeira vez por Alexander Shulgin. Em seu livro PiHKAL, Shulgin relatou ter consumido Ariadne até uma dose de 32mg, relatando que a droga produz psicodelia em um limiar mínimo - sendo, desse modo, um alucinógeno potente em termos de dose-efeito. Existem poucos dados sobre as propriedades farmacológicas, metabolismo e de toxicidade da Ariadne em humanos. Em um estudo com animais, Ariadne mostrou produzir generalização de estímulos em ratos treinados para responder ao medicamento MDMA . (pt) |
dbo:alternativeName | 4-Methyl-2,5-dimethoxybutanamine (en) 4-Methyl-2,5-dimethoxy-alpha-ethylphenethylamine (en) |
dbo:iupacName | 1-(2,5-Dimethoxy-4-methylphenyl)butan-2-amine (en) |
dbo:thumbnail | wiki-commons:Special:FilePath/Ariadne.svg?width=300 |
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dbp:imagefile | Ariadne.svg (en) |
dbp:name | Ariadne (en) |
dbp:othernames | 4 (xsd:integer) |
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dcterms:subject | dbc:Entactogens_and_empathogens dbc:Serotonin-norepinephrine-dopamine_releasing_agents dbc:2,5-Dimethoxyphenethylamines dbc:Substituted_amphetamines |
gold:hypernym | dbr:Drug |
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rdfs:comment | 4-メチル-2,5-ジメトキシ-α-エチルフェネチルアミン(4-methyl-2,5-dimethoxy-alpha-ethylphenethylamine)は、幻覚剤の一つ。アリアドネ(ariadne)、ジモキサミン(dimoxamine)またはα-Et-DOMとも呼ばれる。との類縁体である。アレクサンダー・シュルギンにより初めて合成された。シュルギンの著書PiHKALでは、32 mgの服用で幻覚作用を引き起こすと報告している。この物質のヒトに対する薬理学特性、代謝および毒性のデータはシュルギンによるもののみである。 (ja) Dimoksamina, ariadna – organiczny związek chemiczny z grupy psychodelicznych fenyloetyloamin, homolog 2C-D i DOM. Zsyntezowana po raz pierwszy przez Alexandra Shulgina, opisana w PiHKAL z dawkowaniem do 32 mg oraz nieokreślonym czasem trwania efektów. (pl) Ariadne (also known as 4C-D, 4C-DOM, α-Et-2C-D, BL-3912, or dimoxamine) is a lesser-known psychedelic drug. It is a homologue of 2C-D and DOM. Ariadne was first synthesized by Alexander Shulgin. In his book PiHKAL, Shulgin reported testing Ariadne up to a dose of 32 mg, and reported that it produces psychedelia at a bare threshold. Very little data exists about the pharmacological properties, metabolism, and toxicity of Ariadne in humans apart from Shulgin's limited testing. In an animal study, Ariadne was shown to produce stimulus generalization in rats trained to respond to the drug MDMA. (en) Ariadne (também conhecido como 4C-D, 4C-DOM, α-Et-2C-D, BL-3912 ou dimoxamina) é uma droga psicodélica pouco conhecida. É um homólogo do 2C-D e dimetoxianfetamina (DOM). Ariadne foi sintetizado pela primeira vez por Alexander Shulgin. Em seu livro PiHKAL, Shulgin relatou ter consumido Ariadne até uma dose de 32mg, relatando que a droga produz psicodelia em um limiar mínimo - sendo, desse modo, um alucinógeno potente em termos de dose-efeito. Existem poucos dados sobre as propriedades farmacológicas, metabolismo e de toxicidade da Ariadne em humanos. (pt) |
rdfs:label | Ariadne (psychedelic) (en) 4-メチル-2,5-ジメトキシ-α-エチルフェネチルアミン (ja) Dimoksamina (pl) Ariadne (droga) (pt) |
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foaf:depiction | wiki-commons:Special:FilePath/Ariadne.svg |
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foaf:name | Ariadne (en) |
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