B recognition element (original) (raw)

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dbo:abstract The B recognition element (BRE) is a DNA sequence found in the promoter region of most genes in eukaryotes and Archaea. The BRE is a cis-regulatory element that is found immediately near TATA box, and consists of 7 nucleotides. There are two sets of BREs: one (BREu) found immediately upstream of the TATA box, with the consensus SSRCGCC; the other (BREd) found around 7 nucleotides downstream, with the consensus RTDKKKK. The BREu was discovered in 1998 by Richard Ebright and co-workers. The BREd was named in 2005 by Deng and Roberts; such a downstream recognition was reported earlier in 2000 in Tsai and Sigler's crystal structure. (en) Элемент распознавания В (BRE) — последовательность ДНК, найденная в промоторной области большинства генов в эукариот и архей. BRE является цис-регуляторным элементом, который находится выше ТАТА-бокса, и состоит из 7 нуклеотидов. BRE был открыт в 1998 году Ричардом Эбрайтом (англ. Richard Ebright) и сотрудниками (ru)
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dct:subject dbc:Regulatory_sequences
gold:hypernym dbr:Sequence
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rdfs:comment Элемент распознавания В (BRE) — последовательность ДНК, найденная в промоторной области большинства генов в эукариот и архей. BRE является цис-регуляторным элементом, который находится выше ТАТА-бокса, и состоит из 7 нуклеотидов. BRE был открыт в 1998 году Ричардом Эбрайтом (англ. Richard Ebright) и сотрудниками (ru) The B recognition element (BRE) is a DNA sequence found in the promoter region of most genes in eukaryotes and Archaea. The BRE is a cis-regulatory element that is found immediately near TATA box, and consists of 7 nucleotides. There are two sets of BREs: one (BREu) found immediately upstream of the TATA box, with the consensus SSRCGCC; the other (BREd) found around 7 nucleotides downstream, with the consensus RTDKKKK. (en)
rdfs:label B recognition element (en) BRE (ru)
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