dbo:abstract |
In enzymology, a bilirubin oxidase, BOD or BOx, (EC 1.3.3.5) is an enzyme encoded by a gene in various organisms that catalyzes the chemical reaction 2 bilirubin + O2 2 biliverdin + 2 H2O This enzyme belongs to the family of oxidoreductases, to be specific those acting on the CH-CH group of donor with oxygen as acceptor. The systematic name of this enzyme class is bilirubin:oxygen oxidoreductase. This enzyme is also called bilirubin oxidase M-1. This enzyme participates in porphyrin and chlorophyll metabolism. It is widely studied as a catalyst for oxygen reduction. Two structures of bilirubin oxidase from the ascomycete Myrothecium verrucaria have been deposited in the Protein Data Bank (accession codes 3abg and 2xll). The active site consists of four copper centers, reminiscent of laccase. These centers are classified as type I (cys, met, his, his), type II (3his), and two type III (2his). (en) ビリルビンオキシダーゼ(bilirubin oxidase)は、次の化学反応を触媒する酸化還元酵素である。 2 ビリルビン + O2 2 ビリベルジン + 2 H2O 反応式の通り、この酵素の基質はビリルビンと酸素、生成物はビリベルジンと水である。 * ビリルビン * ビリベルジン 組織名はbilirubin:oxygen oxidoreductaseで、別名にbilirubin oxidase M-1がある。 (ja) La bilirubina ossidasi è un enzima appartenente alla classe delle ossidoreduttasi, che catalizza la seguente reazione: 2 bilirubina + O2 ⇄ 2 biliverdina + 2 H2O (it) |
dbo:ecNumber |
1.3.3.5 |
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wiki-commons:Special:FilePath/MvBO_2xll_thumb.png?width=300 |
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dbp:caption |
Cartoon representation of the X-ray structure of bilirubin oxidase from Myrothecium verrucaria based on PDB accession code . The protein ribbon is rainbow colored with the N-terminus in blue and the C-terminus in red. The four copper atoms are shown as spheres and the glycans shown as sticks. (en) |
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bilirubin oxidase (en) |
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rdfs:comment |
ビリルビンオキシダーゼ(bilirubin oxidase)は、次の化学反応を触媒する酸化還元酵素である。 2 ビリルビン + O2 2 ビリベルジン + 2 H2O 反応式の通り、この酵素の基質はビリルビンと酸素、生成物はビリベルジンと水である。 * ビリルビン * ビリベルジン 組織名はbilirubin:oxygen oxidoreductaseで、別名にbilirubin oxidase M-1がある。 (ja) La bilirubina ossidasi è un enzima appartenente alla classe delle ossidoreduttasi, che catalizza la seguente reazione: 2 bilirubina + O2 ⇄ 2 biliverdina + 2 H2O (it) In enzymology, a bilirubin oxidase, BOD or BOx, (EC 1.3.3.5) is an enzyme encoded by a gene in various organisms that catalyzes the chemical reaction 2 bilirubin + O2 2 biliverdin + 2 H2O This enzyme belongs to the family of oxidoreductases, to be specific those acting on the CH-CH group of donor with oxygen as acceptor. The systematic name of this enzyme class is bilirubin:oxygen oxidoreductase. This enzyme is also called bilirubin oxidase M-1. This enzyme participates in porphyrin and chlorophyll metabolism. It is widely studied as a catalyst for oxygen reduction. (en) |
rdfs:label |
Bilirubin oxidase (en) Bilirubina ossidasi (it) ビリルビンオキシダーゼ (ja) |
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