BindingDB (original) (raw)
BindingDB is a public, web-accessible database of measured binding affinities, focusing chiefly on the interactions of proteins considered to be candidate drug-targets with ligands that are small, drug-like molecules. As of March, 2011, BindingDB contains about 650,000 binding data, for 5,700 protein targets and 280,000 small molecules. BindingDB also includes a small collection of host–guest binding data of interest to chemists studying supramolecular systems.
| Property | Value |
|---|---|
| dbo:abstract | BindingDB is a public, web-accessible database of measured binding affinities, focusing chiefly on the interactions of proteins considered to be candidate drug-targets with ligands that are small, drug-like molecules. As of March, 2011, BindingDB contains about 650,000 binding data, for 5,700 protein targets and 280,000 small molecules. BindingDB also includes a small collection of host–guest binding data of interest to chemists studying supramolecular systems. The purpose of BindingDB is to support medicinal chemistry and drug discovery via literature awareness and development of structure-activity relations (SAR and QSAR); validation of computational chemistry and molecular modelling approaches such as docking, scoring and free energy methods; chemical biology and chemical genomics; and basic studies of the physical chemistry of molecular recognition. The data collection derives from a variety of measurement techniques, including enzyme inhibition and kinetics, isothermal titration calorimetry, NMR, and radioligand and competition assays. BindingDB includes data extracted from the scientific literature by the BindingDB project, selected PubChem confirmatory BioAssays, and ChEMBL entries for which a well-defined protein target ("TARGET_TYPE='PROTEIN'") is provided. (en) |
| dbo:thumbnail | wiki-commons:Special:FilePath/Glow-mkg1a_small.jpg?width=300 |
| dbo:wikiPageExternalLink | http://bindingDB.org/ http://gilson.ucsd.edu/ http://www.bindingdb.org/bind/info.jsp http://www.scivee.tv/browse%3Fbrfl=bindingdb http://www.bindingdb.org/bind/chemsearch/marvin/PolicyNotice.jsp%3Fall_download=yes http://bindingDB.org |
| dbo:wikiPageID | 31213240 (xsd:integer) |
| dbo:wikiPageLength | 5285 (xsd:nonNegativeInteger) |
| dbo:wikiPageRevisionID | 878214714 (xsd:integer) |
| dbo:wikiPageWikiLink | dbr:N-ethylmaleimide_sensitive_fusion_protein dbr:NIH dbr:Host–guest_chemistry dbr:PubChem dbr:Chemical_database dbr:NIST dbr:Computational_chemistry dbr:Docking_(molecular) dbc:Biological_databases dbr:Molecular_recognition dbc:Medicinal_chemistry dbr:ChEMBL dbr:Biological_activity dbr:Molecular_modelling dbr:SAMPL_Challenge dbr:UC_San_Diego dbr:File:Glow-mkg1a_small.jpg dbr:Creative_Commons_Attribution-Share_Alike dbr:Skaggs_School_of_Pharmacy_and_Pharmaceutical_Sciences |
| dbp:author | Michael Gilson, Team Leader (en) |
| dbp:bot | InternetArchiveBot (en) |
| dbp:date | November 2016 (en) |
| dbp:description | dbr:Chemical_database |
| dbp:download | http://www.bindingdb.org/bind/chemsearch/marvin/PolicyNotice.jsp%3Fall_download=yes |
| dbp:fixAttempted | yes (en) |
| dbp:license | The BindingDB data is made available on a Creative Commons Attribution-Share Alike 3.0 Unported License (en) |
| dbp:logo | dbr:File:Glow-mkg1a_small.jpg |
| dbp:pmid | 17145705 (xsd:integer) |
| dbp:released | 1995 (xsd:integer) |
| dbp:scope | Molecules with drug-like properties and biological activity (en) |
| dbp:url | http://bindingDB.org |
| dbp:wikiPageUsesTemplate | dbt:Infobox_biodatabase dbt:Dead_link dbt:Reflist |
| dc:description | Chemical database |
| dct:subject | dbc:Biological_databases dbc:Medicinal_chemistry |
| gold:hypernym | dbr:Database |
| rdf:type | owl:Thing schema:CreativeWork dbo:Work wikidata:Q386724 dbo:Database dul:InformationObject dbo:BiologicalDatabase |
| rdfs:comment | BindingDB is a public, web-accessible database of measured binding affinities, focusing chiefly on the interactions of proteins considered to be candidate drug-targets with ligands that are small, drug-like molecules. As of March, 2011, BindingDB contains about 650,000 binding data, for 5,700 protein targets and 280,000 small molecules. BindingDB also includes a small collection of host–guest binding data of interest to chemists studying supramolecular systems. (en) |
| rdfs:label | BindingDB (en) |
| owl:sameAs | freebase:BindingDB wikidata:BindingDB https://global.dbpedia.org/id/4YpoC |
| prov:wasDerivedFrom | wikipedia-en:BindingDB?oldid=878214714&ns=0 |
| foaf:depiction | wiki-commons:Special:FilePath/Glow-mkg1a_small.jpg |
| foaf:homepage | http://bindingDB.org |
| foaf:isPrimaryTopicOf | wikipedia-en:BindingDB |
| is dbo:wikiPageWikiLink of | dbr:Ligand_(biochemistry) dbr:PubChem dbr:Chemical_database dbr:Stability_constants_of_complexes dbr:Druggability dbr:Biological_target dbr:Avidity dbr:SAMPL_Challenge |
| is foaf:primaryTopic of | wikipedia-en:BindingDB |
