| dbo:abstract |
CXC chemokine receptors are integral membrane proteins that specifically bind and respond to cytokines of the CXC chemokine family. They represent one subfamily of chemokine receptors, a large family of G protein-linked receptors that are known as seven transmembrane (7-TM) proteins, since they span the cell membrane seven times. There are currently six known CXC chemokine receptors in mammals, named CXCR1 through CXCR6. (en) |
| dbo:arm |
p21 q21 q13 q23 q35 |
| dbo:chromosome |
2 11 3 X |
| dbo:entrezgene |
643 10663 2833 3577 3579 7852 |
| dbo:omim |
146928 (xsd:integer) 146929 (xsd:integer) 162643 (xsd:integer) 300574 (xsd:integer) 601613 (xsd:integer) 605163 (xsd:integer) |
| dbo:refseq |
NM_000634 NM_001008540 NM_001504 NM_001557 NM_001716 NM_006564 |
| dbo:symbol |
BLR1 CXCR3 CXCR4 CXCR6 IL8RA IL8RB |
| dbo:uniprot |
O00574 P25024 P25025 P32302 P49682 P61073 |
| dbo:wikiPageExternalLink |
http://www.iuphar-db.org/GPCR/ChapterMenuForward%3FchapterID=1280 |
| dbo:wikiPageID |
9833578 (xsd:integer) |
| dbo:wikiPageLength |
9030 (xsd:nonNegativeInteger) |
| dbo:wikiPageRevisionID |
1110466777 (xsd:integer) |
| dbo:wikiPageWikiLink |
dbr:Dendritic_cells dbr:Cytokine dbr:Integral_membrane_protein dbr:Memory_B_cells dbr:Chemokine_receptor dbr:Chemotaxis dbr:Gene dbr:Monocytes dbr:Macrophages dbr:B_cells dbr:G_protein-coupled_receptor dbr:Cell_membrane dbr:Chromosome_3 dbr:Hematopoietic dbr:ACKR3 dbc:Chemokine_receptors dbr:Chemokine dbr:Chemokines dbr:CXCL1 dbr:CXCL10 dbr:CXCL11 dbr:CXCL13 dbr:CXCL16 dbr:CXCL6 dbr:CXCL7 dbr:CXCL9 dbr:CXCR3 dbr:CXCR4 dbr:CXCR5 dbr:CXCR6 dbr:Langerhans_cells dbr:T_cell dbr:Lymphoid_tissue dbr:Neuronal dbr:Neutrophils dbr:IL8RA dbr:IL8RB dbr:Interleukin-8 dbr:CXCL12 dbr:Nerve_cells dbr:Lymphocyte_homing |
| dbp:arm |
p21 (en) q21 (en) q13 (en) q23 (en) q35 (en) |
| dbp:chromosome |
2 (xsd:integer) 3 (xsd:integer) 11 (xsd:integer) X (en) |
| dbp:entrezgene |
643 (xsd:integer) 2833 (xsd:integer) 3577 (xsd:integer) 3579 (xsd:integer) 7852 (xsd:integer) 10663 (xsd:integer) |
| dbp:name |
dbr:CXCR3 dbr:CXCR4 dbr:CXCR5 dbr:CXCR6 dbr:IL8RA dbr:IL8RB |
| dbp:omim |
146928 (xsd:integer) 146929 (xsd:integer) 162643 (xsd:integer) 300574 (xsd:integer) 601613 (xsd:integer) 605163 (xsd:integer) |
| dbp:refseq |
NM_000634 (en) NM_001008540 (en) NM_001504 (en) NM_001557 (en) NM_001716 (en) NM_006564 (en) |
| dbp:symbol |
BLR1 (en) CXCR3 (en) CXCR4 (en) CXCR6 (en) IL8RA (en) IL8RB (en) |
| dbp:uniprot |
O00574 (en) P25024 (en) P25025 (en) P32302 (en) P49682 (en) P61073 (en) |
| dbp:wikiPageUsesTemplate |
dbt:Cite_web dbt:Reflist dbt:Short_description dbt:Infobox_protein dbt:Chemokine_receptor_modulators dbt:Chemokine_receptors |
| dcterms:subject |
dbc:Chemokine_receptors |
| gold:hypernym |
dbr:Proteins |
| rdf:type |
owl:Thing dbo:Biomolecule wikidata:Q206229 wikidata:Q8054 yago:WikicatChemokineReceptors yago:BodyPart105220461 yago:Part109385911 yago:PhysicalEntity100001930 yago:Receptor105608868 dbo:Protein yago:Structure105225602 yago:Thing100002452 umbel-rc:ProteinMolecule |
| rdfs:comment |
CXC chemokine receptors are integral membrane proteins that specifically bind and respond to cytokines of the CXC chemokine family. They represent one subfamily of chemokine receptors, a large family of G protein-linked receptors that are known as seven transmembrane (7-TM) proteins, since they span the cell membrane seven times. There are currently six known CXC chemokine receptors in mammals, named CXCR1 through CXCR6. (en) |
| rdfs:label |
CXC chemokine receptors (en) |
| owl:sameAs |
freebase:CXC chemokine receptors wikidata:CXC chemokine receptors https://global.dbpedia.org/id/4e7Jg |
| prov:wasDerivedFrom |
wikipedia-en:CXC_chemokine_receptors?oldid=1110466777&ns=0 |
| foaf:isPrimaryTopicOf |
wikipedia-en:CXC_chemokine_receptors |
| foaf:name |
CXCR3 (en) CXCR4 (en) CXCR6 (en) CXCR1 (en) CXCR2 (en) CXCR5 (en) |
| is dbo:wikiPageRedirects of |
dbr:CXC_chemokine_receptor dbr:CXCR dbr:CXC_receptor dbr:Cxc_motif |
| is dbo:wikiPageWikiLink of |
dbr:Rhodopsin-like_receptors dbr:Index_of_immunology_articles dbr:Intravascular_lymphomas dbr:Stromal_cell-derived_factor_1 dbr:Chemokine_receptor dbr:Chemokine dbr:CXCL16 dbr:CXCL2 dbr:CXCL3 dbr:CXCL5 dbr:CXCL6 dbr:CXCL9 dbr:CXCR3 dbr:CXCR5 dbr:CXC_chemokine_receptor dbr:Outline_of_immunology dbr:CXCR dbr:CXC_receptor dbr:Cxc_motif |
| is foaf:primaryTopic of |
wikipedia-en:CXC_chemokine_receptors |