Calexcitin (original) (raw)

Calexcitin is a calcium-binding protein first isolated from the sea snail Hermissenda crassicornis. It is upregulated following Pavlovian conditioning. Calexcitin has four EF-hand motifs that possess different functions while the fourth one is nonfunctional. Calexcitin has the tendency to regulate K+ channels. In addition, Calexcitin also shows a sign of GTP binding protein in which that binds to Ca2+. Calexcitin is neuronal-specific and becomes phosphorylated and upregulated in learning of association.