| dbo:abstract |
كاروكسازون هو مضاد اكتئاب مثبط أكسيداز أحادي الأمين عكوس يثبط أكثر من بخمس مرات. استخدم في علاج الاضطراب الاكتئابي لكنه غير متوفر حاليا. (ar) Caroxazone (Surodil, Timostenil) is an antidepressant which was formerly used for the treatment of depression but is now no longer marketed. It acts as a reversible monoamine oxidase inhibitor (RIMA) of both MAO-A and MAO-B subtypes, with five-fold preference for the latter. (en) A caroxazona (nomes comerciais: Surodil, Timostenil, entre outros) é um antidepressivo utilizado em tratamento de depressão, mas que foi amplamente descontinuado e não é mais comercializado. Atua como um inibidor reversível da monoamina oxidase (IRMA) em suas duas isoformas, MAO-A e , com afinidade de ligação cinco vezes maior para o MAO-B. (pt) |
| dbo:casNumber |
18464-39-6 |
| dbo:chEMBL |
2104164 |
| dbo:fdaUniiCode |
807N226MNL |
| dbo:pubchem |
29083 |
| dbo:thumbnail |
wiki-commons:Special:FilePath/Caroxazone.png?width=300 |
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26340302 (xsd:integer) |
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5382 (xsd:nonNegativeInteger) |
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1075188816 (xsd:integer) |
| dbo:wikiPageWikiLink |
dbr:Enzyme_inhibitor dbr:Mouth dbc:Benzoxazines dbr:Reversible_inhibitor_of_monoamine_oxidase_A dbc:Carbamates dbr:Salicylaldehyde dbr:Glycinamide dbr:Monoamine_oxidase_inhibitor dbr:NaHCO3 dbr:Antidepressant dbr:Major_depressive_disorder dbr:Paraxazone dbr:Isomer dbr:Phosgene dbr:Reductive_amination dbr:MAO-A dbr:MAO-B dbr:File:Caroxazone_synthesis.svg |
| dbp:atcPrefix |
none (en) |
| dbp:c |
10 (xsd:integer) |
| dbp:casNumber |
18464 (xsd:integer) |
| dbp:chembl |
2104164 (xsd:integer) |
| dbp:chemspiderid |
27057 (xsd:integer) |
| dbp:h |
10 (xsd:integer) |
| dbp:iupacName |
2 (xsd:integer) |
| dbp:legalStatus |
Rx-only (en) |
| dbp:n |
2 (xsd:integer) |
| dbp:o |
3 (xsd:integer) |
| dbp:pregnancyCategory |
? (en) |
| dbp:pubchem |
29083 (xsd:integer) |
| dbp:routesOfAdministration |
dbr:Mouth |
| dbp:smiles |
O=CCN2COc1ccccc1C2 (en) |
| dbp:unii |
807 (xsd:integer) |
| dbp:wikiPageUsesTemplate |
dbt:Drugbox dbt:Reflist dbt:Fdacite dbt:Antidepressants dbt:Anxiolytics dbt:Monoamine_metabolism_modulators |
| dcterms:subject |
dbc:Benzoxazines dbc:Carbamates |
| gold:hypernym |
dbr:Antidepressant |
| rdf:type |
owl:Thing dul:ChemicalObject dbo:ChemicalSubstance wikidata:Q8386 yago:WikicatCarbamates yago:Abstraction100002137 yago:Carbamate114792281 yago:Chemical114806838 yago:Compound114818238 yago:Material114580897 yago:Matter100020827 yago:Part113809207 yago:PhysicalEntity100001930 yago:Relation100031921 dbo:Drug yago:Salt115010703 yago:Substance100019613 umbel-rc:DrugProduct |
| rdfs:comment |
كاروكسازون هو مضاد اكتئاب مثبط أكسيداز أحادي الأمين عكوس يثبط أكثر من بخمس مرات. استخدم في علاج الاضطراب الاكتئابي لكنه غير متوفر حاليا. (ar) Caroxazone (Surodil, Timostenil) is an antidepressant which was formerly used for the treatment of depression but is now no longer marketed. It acts as a reversible monoamine oxidase inhibitor (RIMA) of both MAO-A and MAO-B subtypes, with five-fold preference for the latter. (en) A caroxazona (nomes comerciais: Surodil, Timostenil, entre outros) é um antidepressivo utilizado em tratamento de depressão, mas que foi amplamente descontinuado e não é mais comercializado. Atua como um inibidor reversível da monoamina oxidase (IRMA) em suas duas isoformas, MAO-A e , com afinidade de ligação cinco vezes maior para o MAO-B. (pt) |
| rdfs:label |
كاروكسازون (ar) Caroxazone (en) Caroxazona (pt) |
| owl:sameAs |
freebase:Caroxazone wikidata:Caroxazone dbpedia-ar:Caroxazone dbpedia-fa:Caroxazone dbpedia-pt:Caroxazone dbpedia-sh:Caroxazone dbpedia-sr:Caroxazone dbpedia-vi:Caroxazone https://global.dbpedia.org/id/4g8qR yago-res:Caroxazone |
| prov:wasDerivedFrom |
wikipedia-en:Caroxazone?oldid=1075188816&ns=0 |
| foaf:depiction |
wiki-commons:Special:FilePath/Caroxazone.png wiki-commons:Special:FilePath/Caroxazone_synthesis.svg |
| foaf:isPrimaryTopicOf |
wikipedia-en:Caroxazone |
| is dbo:wikiPageWikiLink of |
dbr:List_of_adrenergic_drugs dbr:List_of_antidepressants dbr:List_of_dopaminergic_drugs dbr:Monoamine_oxidase_inhibitor dbr:Paraxazone dbr:C10H10N2O3 dbr:List_of_drugs:_C–Ca |
| is foaf:primaryTopic of |
wikipedia-en:Caroxazone |
