| dbo:abstract |
Cephalosporin C is an antibiotic of the cephalosporin class. It was isolated from a fungus of the genus Acremonium and first characterized in 1961. Although not a very active antibiotic itself, synthetic analogs of cephalosporin C, such as cefalotin, became some of the first marketed cephalosporin antibiotic drugs. Cephalosporin C strongly absorbs ultraviolet light, is stable to acid, is non-toxic and has in vivo activity in mice. Cephalosporin C, which has a similar structure to penicillin N, was never commercialized. Cephalosporin C was a lead compound for the discovery and production of many other cephalosporins. Cephalosporins are drugs used for some people who are allergic to penicillin. (en) La céphalosporine C est un antibiotique de la classe des céphalosporines. Elle a été isolée de mycètes du genre (en) et caractérisée pour la première fois en 1961. Bien qu'elle ne soit pas elle-même un antibiotique très actif, des analogues synthétiques de la céphalosporine C tels que la céfalotine sont devenus des céphalosporines parmi les plus distribuées commercialement. (fr) セファロスポリンC（Cephalosporin C）は、アクレモニウム属の真菌から得られたセフェム系抗菌薬である。 (ja) |
| dbo:alternativeName |
7-(5-Amino-5-carboxyvaleramido)cephalosporanic acid (en) |
| dbo:iupacName |
(6R,7R)-3-[(Acetyloxy)methyl]-7-[(5R)-5-amino-5-carboxypentanamido]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid (en) |
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Cephalosporin C.svg (en) |
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dbc:Cephalosporin_antibiotics |
| gold:hypernym |
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| rdf:type |
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| rdfs:comment |
La céphalosporine C est un antibiotique de la classe des céphalosporines. Elle a été isolée de mycètes du genre (en) et caractérisée pour la première fois en 1961. Bien qu'elle ne soit pas elle-même un antibiotique très actif, des analogues synthétiques de la céphalosporine C tels que la céfalotine sont devenus des céphalosporines parmi les plus distribuées commercialement. (fr) セファロスポリンC（Cephalosporin C）は、アクレモニウム属の真菌から得られたセフェム系抗菌薬である。 (ja) Cephalosporin C is an antibiotic of the cephalosporin class. It was isolated from a fungus of the genus Acremonium and first characterized in 1961. Although not a very active antibiotic itself, synthetic analogs of cephalosporin C, such as cefalotin, became some of the first marketed cephalosporin antibiotic drugs. Cephalosporin C strongly absorbs ultraviolet light, is stable to acid, is non-toxic and has in vivo activity in mice. Cephalosporin C, which has a similar structure to penicillin N, was never commercialized. (en) |
| rdfs:label |
Cephalosporin C (en) Céphalosporine C (fr) セファロスポリンC (ja) |
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