| dbo:abstract |
سيفيميلين (بالإنجليزية: Cevimeline) هو دواء يُستعمل في علاج: * متلازمة شوغرن (ar) Cevimeline (trade name Evoxac) is a synthetic analog of the natural alkaloid muscarine with a particular agonistic effect on M1 and M3 receptors. It is used in the treatment of dry mouth and Sjögren's syndrome. (en) セビメリン（英:cevimeline）はアセチルコリン類似化合物の一つ。唾液腺に分布するムスカリン性アセチルコリン受容体に作用して、唾液分泌を促進する。主に口渇が症状として現れる疾患に、対症療法として用いられる。 (ja) La cevimelina è un farmaco parasimpaticomimetico e , con particolare selettività verso i recettori muscarinici M3. Nel 2000 è stato approvato dalla Food and Drug Administration per il trattamento della xerostomia nei pazienti affetti da sindrome di Sjögren. (it) |
| dbo:alternativeName |
Evoxac (en) |
| dbo:casNumber |
107233-08-9 |
| dbo:chEBI |
3568 |
| dbo:chEMBL |
1201267 |
| dbo:drugbank |
DB00185 |
| dbo:fdaUniiCode |
K9V0CDQ56E |
| dbo:kegg |
D07667 |
| dbo:medlinePlus |
a608025 |
| dbo:pubchem |
83898 |
| dbo:thumbnail |
wiki-commons:Special:FilePath/Cevimeline.svg?width=300 |
| dbo:wikiPageExternalLink |
http://www.evoxac.com/ |
| dbo:wikiPageID |
7361176 (xsd:integer) |
| dbo:wikiPageLength |
4545 (xsd:nonNegativeInteger) |
| dbo:wikiPageRevisionID |
1061828160 (xsd:integer) |
| dbo:wikiPageWikiLink |
dbr:Angle_closure_glaucoma dbr:Bethanechol dbc:Oxathiolanes dbr:Rash dbc:Spiro_compounds dbr:Cough dbr:Nausea dbr:Oral_administration dbr:Muscarine dbr:Blurred_vision dbr:Hot_flash dbr:Muscarinic_acetylcholine_receptor_M1 dbr:Muscarinic_acetylcholine_receptor_M3 dbc:Muscarinic_agonists dbc:Daiichi_Sankyo dbr:Capsule_(pharmacy) dbr:Diarrhea dbr:Vomiting dbr:Headache dbr:Asthma dbc:Quinuclidines dbr:Sweating dbr:Drowsiness dbr:Salivary_gland dbr:Pilocarpine dbr:Insomnia dbr:Sjögren's_syndrome dbr:Parasympathetic_nervous_system dbr:Xerostomia dbr:Runny_nose |
| dbp:atcPrefix |
N07 (en) |
| dbp:atcSuffix |
AX03 (en) |
| dbp:c |
10 (xsd:integer) |
| dbp:casNumber |
107233 (xsd:integer) |
| dbp:chebi |
3568 (xsd:integer) |
| dbp:chembl |
1201267 (xsd:integer) |
| dbp:chemspiderid |
75707 (xsd:integer) |
| dbp:drugbank |
DB00185 (en) |
| dbp:h |
17 (xsd:integer) |
| dbp:image |
Cevimeline 3D.png (en) |
| dbp:iupacName |
-2 (xsd:integer) |
| dbp:kegg |
D07667 (en) |
| dbp:legalStatus |
Rx-only (en) |
| dbp:medlineplus |
a608025 (en) |
| dbp:n |
1 (xsd:integer) |
| dbp:o |
1 (xsd:integer) |
| dbp:pregnancyCategory |
C (en) |
| dbp:proteinBound |
<20% (en) |
| dbp:pubchem |
83898 (xsd:integer) |
| dbp:routesOfAdministration |
By mouth (en) |
| dbp:s |
1 (xsd:integer) |
| dbp:smiles |
O1[C@H]C (en) |
| dbp:stdinchi |
1 (xsd:integer) |
| dbp:stdinchikey |
WUTYZMFRCNBCHQ-PSASIEDQSA-N (en) |
| dbp:tradename |
Evoxac (en) |
| dbp:unii |
K9V0CDQ56E (en) |
| dbp:verifiedfields |
changed (en) |
| dbp:verifiedrevid |
460027190 (xsd:integer) |
| dbp:watchedfields |
changed (en) |
| dbp:width |
175 (xsd:integer) |
| dbp:wikiPageUsesTemplate |
dbt:Citation_needed dbt:Drugbox dbt:Reflist dbt:Cascite dbt:Chemspidercite dbt:Drugbankcite dbt:Ebicite dbt:Fdacite dbt:Keggcite dbt:Stdinchicite dbt:Drugs.com dbt:Muscarinic_acetylcholine_receptor_modulators |
| dcterms:subject |
dbc:Oxathiolanes dbc:Spiro_compounds dbc:Muscarinic_agonists dbc:Daiichi_Sankyo dbc:Quinuclidines |
| gold:hypernym |
dbr:Agonist |
| rdf:type |
owl:Thing dul:ChemicalObject dbo:ChemicalSubstance wikidata:Q8386 yago:WikicatMolecularFormulas yago:WikicatSpiroCompounds yago:Abstraction100002137 yago:Cognition100023271 yago:Communication100033020 yago:Compound105870180 yago:Concept105835747 yago:Content105809192 yago:Formula106816935 yago:Idea105833840 yago:Message106598915 yago:MolecularFormula106817173 yago:PsychologicalFeature100023100 dbo:Drug yago:Statement106722453 yago:Whole105869584 umbel-rc:DrugProduct |
| rdfs:comment |
سيفيميلين (بالإنجليزية: Cevimeline) هو دواء يُستعمل في علاج: * متلازمة شوغرن (ar) Cevimeline (trade name Evoxac) is a synthetic analog of the natural alkaloid muscarine with a particular agonistic effect on M1 and M3 receptors. It is used in the treatment of dry mouth and Sjögren's syndrome. (en) セビメリン（英:cevimeline）はアセチルコリン類似化合物の一つ。唾液腺に分布するムスカリン性アセチルコリン受容体に作用して、唾液分泌を促進する。主に口渇が症状として現れる疾患に、対症療法として用いられる。 (ja) La cevimelina è un farmaco parasimpaticomimetico e , con particolare selettività verso i recettori muscarinici M3. Nel 2000 è stato approvato dalla Food and Drug Administration per il trattamento della xerostomia nei pazienti affetti da sindrome di Sjögren. (it) |
| rdfs:label |
سيفيميلين (ar) Cevimeline (en) Cevimelina (it) セビメリン (ja) |
| owl:sameAs |
freebase:Cevimeline wikidata:Cevimeline dbpedia-ar:Cevimeline dbpedia-fa:Cevimeline dbpedia-fi:Cevimeline dbpedia-it:Cevimeline http://www4.wiwiss.fu-berlin.de/drugbank/resource/drugs/DB00185 yago-res:Cevimeline dbpedia-ja:Cevimeline http://or.dbpedia.org/resource/ସେଭିମେଲାଇନ dbpedia-ro:Cevimeline dbpedia-sh:Cevimeline dbpedia-sr:Cevimeline https://global.dbpedia.org/id/3PLKh |
| prov:wasDerivedFrom |
wikipedia-en:Cevimeline?oldid=1061828160&ns=0 |
| foaf:depiction |
wiki-commons:Special:FilePath/Cevimeline.svg wiki-commons:Special:FilePath/Cevimeline_3D.png |
| foaf:isPrimaryTopicOf |
wikipedia-en:Cevimeline |
| is dbo:wikiPageRedirects of |
dbr:C10H17NOS dbr:ATC_code_N07AX03 dbr:ATCvet_code_QN07AX03 dbr:Evoxac dbr:Saligren dbr:Cevimeline_hydrochloride |
| is dbo:wikiPageWikiLink of |
dbr:Index_of_oncology_articles dbr:Sjögren_syndrome dbr:Muscarinic_acetylcholine_receptor_M1 dbr:Muscarinic_agonist dbr:C10H17NOS dbr:Daiichi_Sankyo dbr:ATC_code_N07AX03 dbr:ATCvet_code_QN07AX03 dbr:ATC_code_N07 dbr:Salivary_gland dbr:Evoxac dbr:Meth_mouth dbr:List_of_drugs:_Cb–Ce dbr:Saligren dbr:Cevimeline_hydrochloride |
| is foaf:primaryTopic of |
wikipedia-en:Cevimeline |
