Chimerin (original) (raw)

Chimerin is a type of nerve tissue protein. Chimerins are a family of non-PKC phorbol-ester receptors. They were the first to be discovered within this family. They are represented as a family of four closely bound GAPs1 (GTPase-activating proteins). These small GTPases were once characterized as high affinity intracellular receptors for the second messenger diacylglycerol (DAG) and the phorbol ester tumor promoters. β2-chimerin can be linked to a fusion gene that is associated with a key insulin receptor that causes people to have decreased levels of insulin. * Chimerin 1 * Chimerin 2