| dbo:abstract |
Choh Hao Li (auch Cho Hao Li, chin. 李卓皓; * 21. April 1913 in Guangzhou (Kanton), Republik China; † 28. November 1987) war ein chinesisch-US-amerikanischer Biochemiker. Li galt als führend auf dem Gebiet der Biochemie der Hormone der Adenohypophyse (Vorderteil der Hirnanhangsdrüse). (de) Choh Hao Li (sometimes Cho Hao Li) (Chinese: 李卓皓; pinyin: Lǐ Zhuōhào; April 21, 1913 – November 28, 1987) was a Chinese-born American biochemist who discovered, in 1966, that human pituitary growth hormone (somatotropin) consists of a chain of 256 amino acids. In 1970 he succeeded in synthesizing this hormone, the largest protein molecule synthesized up to that time. Li was born in Guangzhou and educated at the Nanjing University. In 1935 he immigrated to the US, where he took up postgraduate studies at the University of California, Berkeley and later joined the staff. He became professor in 1950. He served as Director of the Hormone Research Laboratory at Berkeley from 1950 to 1967 and at UCSF from 1967 until his retirement in 1983. In 1955 he was elected as Academician of Academia Sinica, Republic of China. Li spent his entire academic career studying the pituitary-gland hormones. In collaboration with various co-workers, he isolated several protein hormones, including adrenocorticotropic hormone (ACTH), which stimulates the adrenal cortex to increase its secretion of corticoids. In 1956, Li and his group showed that ACTH consists of 39 amino acids arranged in a specific order, and that the whole chain of the natural hormone is not necessary for its action. He isolated another pituitary hormone called melanocyte-stimulating hormone (MSH) and found that not only does this hormone produce some effects similar to those produced by ACTH, but also that part of the amino acid chain of MSH is the same as that of ACTH. (en) Choh Hao Li (parfois transcrit Cho Hao Li) ((zh); Hanyu pinyin: Lǐ Zhuōhào) (21 avril 1913—28 novembre 1987) est un biochimiste américain d'origine chinoise qui découvre en 1966 que l’hormone de croissance sécrétée par l’hypophyse pituitaire humaine (somatotropine) est une molécule chimique formée d'une chaîne de 191 acides aminés. En 1970 il parvient à synthétiser cette hormone, fabriquant ainsi la plus longue protéine synthétique de l'époque. (fr) Choh Hao Li (Guangzhou, China, 21 de abril de 1913 - Estados Unidos, 28 de novembro de 1987) foi um bioquímico sino-americano. Formado pela Universidade de Nanquim, emigrou em 1935 para os EUA e fez pós-graduação na Universidade da Califórnia, tornando-se professor e pesquisador. Entre pesquisas com glândula pituitária e o hormônio adrenocorticotrófico, Hao Li anunciou em 1971, juntamente com , a obtenção do hormônio responsável pelo crescimento do corpo humano. (pt) 李卓皓（英語：Choh Hao Li，1913年4月21日－1987年11月28日），广东广州人，原籍广东番禺，生物学家。 (zh) |
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http://history.library.ucsf.edu/li.html http://homepage.ntu.edu.tw/~ibs/cp_n_63512.html https://blogs.library.ucsf.edu/broughttolight/2016/09/15/choh-hao-li/ https://www.abjs.org/abjs-corr-nicolas-andry-award-winners https://www.americanpeptidesociety.org/awards.php%3Fawardid=1 https://www.ibc.sinica.edu.tw/ https://www.nap.edu/read/5406/chapter/13%23222 https://www.worldscientific.com/doi/10.1142/9789814704625_0012 https://snaccooperative.org/ark:/99166/w60k39xn https://www.amphilsoc.org/prizes/john-frederick-lewis-award http://www.oac.cdlib.org/findaid/ark:/13030/tf738nb543 https://academic.oup.com/endo/article-abstract/57/5/639/2760045%3FredirectedFrom=PDF https://web.archive.org/web/20071011111320/http:/www.cartage.org.lb/en/themes/Biographies/MainBiographies/L/LiChoHao/1.html https://oac.cdlib.org/findaid/ark:/13030/tf738nb543/entire_text/ http://www.nap.edu/readingroom/books/biomems/cli.html http://www.nasonline.org/publications/biographical-memoirs/memoir-pdfs/li-choh-h.pdf http://pdf.oac.cdlib.org/pdf/ucsf/spcoll/lifindin.pdf |
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Lǐ Zhuōhào (en) |
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Shen-hwai Lu (en) |
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Choh Hao Li (auch Cho Hao Li, chin. 李卓皓; * 21. April 1913 in Guangzhou (Kanton), Republik China; † 28. November 1987) war ein chinesisch-US-amerikanischer Biochemiker. Li galt als führend auf dem Gebiet der Biochemie der Hormone der Adenohypophyse (Vorderteil der Hirnanhangsdrüse). (de) Choh Hao Li (parfois transcrit Cho Hao Li) ((zh); Hanyu pinyin: Lǐ Zhuōhào) (21 avril 1913—28 novembre 1987) est un biochimiste américain d'origine chinoise qui découvre en 1966 que l’hormone de croissance sécrétée par l’hypophyse pituitaire humaine (somatotropine) est une molécule chimique formée d'une chaîne de 191 acides aminés. En 1970 il parvient à synthétiser cette hormone, fabriquant ainsi la plus longue protéine synthétique de l'époque. (fr) Choh Hao Li (Guangzhou, China, 21 de abril de 1913 - Estados Unidos, 28 de novembro de 1987) foi um bioquímico sino-americano. Formado pela Universidade de Nanquim, emigrou em 1935 para os EUA e fez pós-graduação na Universidade da Califórnia, tornando-se professor e pesquisador. Entre pesquisas com glândula pituitária e o hormônio adrenocorticotrófico, Hao Li anunciou em 1971, juntamente com , a obtenção do hormônio responsável pelo crescimento do corpo humano. (pt) 李卓皓（英語：Choh Hao Li，1913年4月21日－1987年11月28日），广东广州人，原籍广东番禺，生物学家。 (zh) Choh Hao Li (sometimes Cho Hao Li) (Chinese: 李卓皓; pinyin: Lǐ Zhuōhào; April 21, 1913 – November 28, 1987) was a Chinese-born American biochemist who discovered, in 1966, that human pituitary growth hormone (somatotropin) consists of a chain of 256 amino acids. In 1970 he succeeded in synthesizing this hormone, the largest protein molecule synthesized up to that time. (en) |
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Choh Hao Li (en) Choh Hao Li (de) Choh Hao Li (fr) Choh Hao Li (pt) 李卓皓 (zh) |
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