Choline oxidase (original) (raw)
In enzymology, a choline oxidase (EC 1.1.3.17) is an enzyme that catalyzes the chemical reaction choline + O2 betaine aldehyde + H2O2 Thus, the two substrates of this enzyme are choline and O2, whereas its two products are betaine aldehyde and H2O2. This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with oxygen as acceptor. The systematic name of this enzyme class is choline:oxygen 1-oxidoreductase. This enzyme participates in glycine, serine, and threonine metabolism. It employs one cofactor, FAD.
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| dbo:abstract | In enzymology, a choline oxidase (EC 1.1.3.17) is an enzyme that catalyzes the chemical reaction choline + O2 betaine aldehyde + H2O2 Thus, the two substrates of this enzyme are choline and O2, whereas its two products are betaine aldehyde and H2O2. This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with oxygen as acceptor. The systematic name of this enzyme class is choline:oxygen 1-oxidoreductase. This enzyme participates in glycine, serine, and threonine metabolism. It employs one cofactor, FAD. (en) コリンオキシダーゼ（Choline oxidase）は、グリシン、セリンおよびトレオニン代謝酵素の一つで、次の化学反応を触媒する酸化還元酵素である。 反応式の通り、この酵素反応は2段階反応である。一段階目の反応の基質はコリンとO2、生成物はとH2O2で、二段階目の反応の基質はベタインアルデヒドとO2とH2O、生成物はベタインとH2O2である。補因子としてFADを用いる。 組織名はcholine:oxygen 1-oxidoreductaseである。 (ja) La colina ossidasi è un enzima appartenente alla classe delle ossidoreduttasi, che catalizza la seguente reazione: colina + O2 ⇄ betaina aldeide + H2O2 L'enzima è una flavoproteina (contenente FAD) che prende parte ad un complesso multienzimatico che ossida anche la betaina aldeide a betaina. In molti batteri, piante ed animali, la betaina viene sintetizzata in due passaggi: 1. * conversione di colina a betaina aldeide; 2. * conversione di betaina aldeide a betaina. Nella prima reazione possono essere coinvolti diversi enzimi. Negli animali ed in molti batteri, essa è catalizzata da questo enzima (la colina ossidasi propriamente detta) o dalla colina deidrogenasi legata alla membrana. Nelle piante, la reazione è invece catalizzata dalla colina monoossigenasi. L'enzima coinvolto nel secondo passaggio, la betaina-aldeide deidrogenasi, è invece lo stesso in piante, animali e batteri. Solo in alcuni batteri, la betaina è sintetizzata dalla glicina attraverso l'azione degli enzimi glicina/sarcosina N-metiltransferasi e sarcosina/dimetilglicina N-metiltransferasi. (it) |
| dbo:ecNumber | 1.1.3.17 |
| dbo:thumbnail | wiki-commons:Special:FilePath/4mjw.jpg?width=300 |
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| dbo:wikiPageLength | 3561 (xsd:nonNegativeInteger) |
| dbo:wikiPageRevisionID | 989132576 (xsd:integer) |
| dbo:wikiPageWikiLink | dbr:List_of_enzymes dbr:Hydrogen_peroxide dbr:Enzymology dbc:EC_1.1.3 dbc:Enzymes_of_known_structure dbc:Flavin_enzymes dbr:Chemical_reaction dbr:Enzyme dbr:Glycine dbr:Substrate_(biochemistry) dbr:Threonine dbr:Flavin_adenine_dinucleotide dbr:Oxygen dbr:Product_(chemistry) dbr:Choline dbr:Cofactor_(biochemistry) dbr:Catalysis dbr:Serine dbr:Oxidoreductase dbr:Betaine_aldehyde |
| dbp:caption | Choline oxidase dimer, Arthrobacter globiformis (en) |
| dbp:casNumber | 9028 (xsd:integer) |
| dbp:ecNumber | 1.100000 (xsd:double) |
| dbp:iubmbEcNumber | 1 (xsd:integer) |
| dbp:name | Choline oxidase (en) |
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| dcterms:subject | dbc:EC_1.1.3 dbc:Enzymes_of_known_structure dbc:Flavin_enzymes |
| rdf:type | owl:Thing dbo:Biomolecule wikidata:Q206229 wikidata:Q8047 yago:Abstraction100002137 yago:Activator114723079 yago:Catalyst114723628 yago:Chemical114806838 yago:Compound114818238 yago:Enzyme114732946 yago:Macromolecule114944888 yago:Material114580897 yago:Matter100020827 yago:Molecule114682133 yago:OrganicCompound114727670 yago:Part113809207 yago:PhysicalEntity100001930 yago:Protein114728724 yago:Relation100031921 dbo:Enzyme yago:Substance100019613 yago:Thing100002452 yago:Unit109465459 yago:WikicatEnzymesOfKnownStructure yago:WikicatFlavinEnzymes |
| rdfs:comment | In enzymology, a choline oxidase (EC 1.1.3.17) is an enzyme that catalyzes the chemical reaction choline + O2 betaine aldehyde + H2O2 Thus, the two substrates of this enzyme are choline and O2, whereas its two products are betaine aldehyde and H2O2. This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with oxygen as acceptor. The systematic name of this enzyme class is choline:oxygen 1-oxidoreductase. This enzyme participates in glycine, serine, and threonine metabolism. It employs one cofactor, FAD. (en) コリンオキシダーゼ（Choline oxidase）は、グリシン、セリンおよびトレオニン代謝酵素の一つで、次の化学反応を触媒する酸化還元酵素である。 反応式の通り、この酵素反応は2段階反応である。一段階目の反応の基質はコリンとO2、生成物はとH2O2で、二段階目の反応の基質はベタインアルデヒドとO2とH2O、生成物はベタインとH2O2である。補因子としてFADを用いる。 組織名はcholine:oxygen 1-oxidoreductaseである。 (ja) La colina ossidasi è un enzima appartenente alla classe delle ossidoreduttasi, che catalizza la seguente reazione: colina + O2 ⇄ betaina aldeide + H2O2 L'enzima è una flavoproteina (contenente FAD) che prende parte ad un complesso multienzimatico che ossida anche la betaina aldeide a betaina. In molti batteri, piante ed animali, la betaina viene sintetizzata in due passaggi: 1. * conversione di colina a betaina aldeide; 2. * conversione di betaina aldeide a betaina. (it) |
| rdfs:label | Choline oxidase (en) Colina ossidasi (it) コリンオキシダーゼ (ja) |
| owl:sameAs | freebase:Choline oxidase yago-res:Choline oxidase wikidata:Choline oxidase dbpedia-fa:Choline oxidase dbpedia-it:Choline oxidase dbpedia-ja:Choline oxidase dbpedia-sh:Choline oxidase dbpedia-sr:Choline oxidase https://global.dbpedia.org/id/2cnY3 |
| prov:wasDerivedFrom | wikipedia-en:Choline_oxidase?oldid=989132576&ns=0 |
| foaf:depiction | wiki-commons:Special:FilePath/4mjw.jpg |
| foaf:isPrimaryTopicOf | wikipedia-en:Choline_oxidase |
| foaf:name | Choline oxidase (en) |
| is dbo:wikiPageRedirects of | dbr:Choline:oxygen_1-oxidoreductase dbr:EC_1.1.3.17 |
| is dbo:wikiPageWikiLink of | dbr:List_of_EC_numbers_(EC_1) dbr:Choline dbr:Arthrobacter_pascens dbr:Choline:oxygen_1-oxidoreductase dbr:EC_1.1.3.17 |
| is foaf:primaryTopic of | wikipedia-en:Choline_oxidase |
