| dbo:abstract |
Cinnamoyl-CoA reductase (EC 1.2.1.44), systematically named cinnamaldehyde:NADP+ oxidoreductase (CoA-cinnamoylating) but commonly referred to by the acronym CCR, is an enzyme that catalyzes the reduction of a substituted cinnamoyl-CoA to its corresponding cinnamaldehyde, utilizing NADPH and H+ and releasing free CoA and NADP+ in the process. Common biologically relevant cinnamoyl-CoA substrates for CCR include p-coumaroyl-CoA and feruloyl-CoA, which are converted into p-coumaraldehyde and coniferaldehyde, respectively, though most CCRs show activity toward a variety of other substituted cinnamoyl-CoA's as well. Catalyzing the first committed step in monolignol biosynthesis, this enzyme plays a critical role in lignin formation, a process important in plants both for structural development and defense response. (en) La cinnamoil-CoA reduttasi è un enzima appartenente alla classe delle ossidoreduttasi, che catalizza la seguente reazione: cinnamaldeide + CoA + NADP+ ⇄ + NADPH + H+ L'enzima agisce anche su un grande numero di esteri cinnamoilici del coenzima A. (it) シンナモイルCoAレダクターゼ（cinnamoyl-CoA reductase）は、フェニルプロパノイド生合成酵素の一つで、次の化学反応を触媒する酸化還元酵素である。 シンナムアルデヒド + CoA + NADP+ シンナモイルCoA + NADPH + H+ 反応式の通り、この酵素の基質はシンナムアルデヒドと補酵素AとNADP+、生成物はシンナモイルCoAとNADPHとH+である。 組織名はcinnamaldehyde:NADP+ oxidoreductase (CoA-cinnamoylating)で、別名にferuloyl-CoA reductase, cinnamoyl-coenzyme A reductase, ferulyl-CoA reductase, feruloyl coenzyme A reductase, p-hydroxycinnamoyl coenzyme A reductase, cinnamoyl-CoA:NADPH reductaseがある。 (ja) |
| dbo:ecNumber |
1.2.1.44 |
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wiki-commons:Special:FilePath/Overall_CCR_Light_Grey_Background.png?width=300 |
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| dbp:caption |
Tertiary structure of CCR1 from Petunia x hybrida colored by secondary structural element, generated from 4R1S (en) |
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59929 (xsd:integer) |
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1 (xsd:integer) |
| dbp:name |
Cinnamoyl-CoA reductase (en) cinnamoyl-CoA reductase (en) |
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dbt:Aldehyde/Oxo_oxidoreductases dbt:EC_number dbt:Enzyme dbt:Enzymes dbt:Not_a_typo dbt:Portal_bar dbt:Reflist |
| dcterms:subject |
dbc:EC_1.2.1 dbc:Enzymes_of_unknown_structure dbc:NADPH-dependent_enzymes |
| rdf:type |
owl:Thing dbo:Biomolecule wikidata:Q206229 wikidata:Q8047 yago:WikicatNADPH-dependentEnzymes yago:Abstraction100002137 yago:Activator114723079 yago:Catalyst114723628 yago:Chemical114806838 yago:Compound114818238 yago:Enzyme114732946 yago:Macromolecule114944888 yago:Material114580897 yago:Matter100020827 yago:Molecule114682133 yago:OrganicCompound114727670 yago:Part113809207 yago:PhysicalEntity100001930 yago:Protein114728724 yago:Relation100031921 dbo:Enzyme yago:Substance100019613 yago:Thing100002452 yago:Unit109465459 yago:WikicatEnzymesOfUnknownStructure |
| rdfs:comment |
La cinnamoil-CoA reduttasi è un enzima appartenente alla classe delle ossidoreduttasi, che catalizza la seguente reazione: cinnamaldeide + CoA + NADP+ ⇄ + NADPH + H+ L'enzima agisce anche su un grande numero di esteri cinnamoilici del coenzima A. (it) シンナモイルCoAレダクターゼ（cinnamoyl-CoA reductase）は、フェニルプロパノイド生合成酵素の一つで、次の化学反応を触媒する酸化還元酵素である。 シンナムアルデヒド + CoA + NADP+ シンナモイルCoA + NADPH + H+ 反応式の通り、この酵素の基質はシンナムアルデヒドと補酵素AとNADP+、生成物はシンナモイルCoAとNADPHとH+である。 組織名はcinnamaldehyde:NADP+ oxidoreductase (CoA-cinnamoylating)で、別名にferuloyl-CoA reductase, cinnamoyl-coenzyme A reductase, ferulyl-CoA reductase, feruloyl coenzyme A reductase, p-hydroxycinnamoyl coenzyme A reductase, cinnamoyl-CoA:NADPH reductaseがある。 (ja) Cinnamoyl-CoA reductase (EC 1.2.1.44), systematically named cinnamaldehyde:NADP+ oxidoreductase (CoA-cinnamoylating) but commonly referred to by the acronym CCR, is an enzyme that catalyzes the reduction of a substituted cinnamoyl-CoA to its corresponding cinnamaldehyde, utilizing NADPH and H+ and releasing free CoA and NADP+ in the process. Common biologically relevant cinnamoyl-CoA substrates for CCR include p-coumaroyl-CoA and feruloyl-CoA, which are converted into p-coumaraldehyde and coniferaldehyde, respectively, though most CCRs show activity toward a variety of other substituted cinnamoyl-CoA's as well. Catalyzing the first committed step in monolignol biosynthesis, this enzyme plays a critical role in lignin formation, a process important in plants both for structural development (en) |
| rdfs:label |
Cinnamoyl-CoA reductase (en) Cinnamoil-CoA reduttasi (it) シンナモイルCoAレダクターゼ (ja) |
| owl:sameAs |
freebase:Cinnamoyl-CoA reductase yago-res:Cinnamoyl-CoA reductase wikidata:Cinnamoyl-CoA reductase dbpedia-it:Cinnamoyl-CoA reductase dbpedia-ja:Cinnamoyl-CoA reductase dbpedia-sh:Cinnamoyl-CoA reductase dbpedia-sr:Cinnamoyl-CoA reductase https://global.dbpedia.org/id/2msPN |
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wikipedia-en:Cinnamoyl-CoA_reductase?oldid=1040525801&ns=0 |
| foaf:depiction |
wiki-commons:Special:FilePath/CCR_mechanism.png wiki-commons:Special:FilePath/Monolignol_Biosynthesis_Pathway.png wiki-commons:Special:FilePath/Overall_CCR_Light_Grey_Background.png |
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wikipedia-en:Cinnamoyl-CoA_reductase |
| foaf:name |
cinnamoyl-CoA reductase (en) |
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dbr:Cinnamaldehyde:NADP+_oxidoreductase_(CoA-cinnamoylating) dbr:EC_1.2.1.44 |
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dbr:Cinnamoyl-CoA dbr:Eugenol dbr:List_of_EC_numbers_(EC_1) dbr:Phenylpropanoids_metabolism dbr:Cinnamaldehyde:NADP+_oxidoreductase_(CoA-cinnamoylating) dbr:EC_1.2.1.44 |
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wikipedia-en:Cinnamoyl-CoA_reductase |
