Codeinone (original) (raw)
Codeinone is 1/3 as active as codeine as an analgesic but it is an important intermediate in the production of hydrocodone, a painkiller about 3/4 the potency of morphine; as well as of oxycodone. The latter can also be synthesized from thebaine, however.
| Property | Value |
|---|---|
| dbo:abstract | Codeinone is 1/3 as active as codeine as an analgesic but it is an important intermediate in the production of hydrocodone, a painkiller about 3/4 the potency of morphine; as well as of oxycodone. The latter can also be synthesized from thebaine, however. (en) La codeinona es un opioide fuerte. Es un producto intermedio en la síntesis de algunos opioides semisintéticos, como la naloxona, naltrexona y la oxicodona. (es) La codéinone est un analgésique trois fois moins actif que la codéine ; mais c'est un produit intermédiaire important de la synthèse de l'hydrocodone, un analgésique possédant, comme l'oxycodone, 75 % de l'activité de la morphine. On peut synthétiser cette dernière à partir de thébaïne. On peut décrire la codéinone comme un méthyléther de la : 3-méthyl-morphinone, ou comme un dérivé cétonique de la codéine : codéine-6-one. (fr) |
| dbo:iupacName | (4R,4aR,7aR,12bS)-9-Methoxy-3-methyl-2,3,4,4a,7,7a-hexahydro-1H-4,12-methano[1]benzofuro[3,2-e]isoquinolin-7-one (en) 3-Methoxy-17-methyl-7,8-didehydro-4,5α-epoxymorphinan-6-one (en) |
| dbo:thumbnail | wiki-commons:Special:FilePath/Codeinone.svg?width=300 |
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| dbo:wikiPageLength | 3151 (xsd:nonNegativeInteger) |
| dbo:wikiPageRevisionID | 1090160404 (xsd:integer) |
| dbo:wikiPageWikiLink | dbr:Alkaloid dbr:Hydrocodone dbc:4,5-Epoxymorphinans dbc:Enones dbc:Mu-opioid_receptor_agonists dbc:Semisynthetic_opioids dbr:Opium dbr:Codeine dbr:Morphinone dbr:Thebaine dbr:Ketone dbr:Analgesic dbc:Catechol_ethers dbr:Oxycodone |
| dbp:imagefile | Codeinone.svg (en) |
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| dcterms:subject | dbc:4,5-Epoxymorphinans dbc:Enones dbc:Mu-opioid_receptor_agonists dbc:Semisynthetic_opioids dbc:Catechol_ethers |
| gold:hypernym | http://dbpedia.org/resource// |
| rdf:type | owl:Thing dul:ChemicalObject dbo:ChemicalSubstance wikidata:Q11173 yago:Abstraction100002137 yago:Chemical114806838 yago:Compound114818238 yago:Element114840755 yago:Ketone114926294 yago:Material114580897 yago:Matter100020827 yago:OrganicCompound114727670 yago:Part113809207 yago:PhysicalEntity100001930 yago:Quintessence114847103 yago:Relation100031921 yago:WikicatKetones dbo:ChemicalCompound yago:Substance100019613 yago:WikicatEthers yago:WikicatPhenolEthers umbel-rc:ChemicalSubstanceType |
| rdfs:comment | Codeinone is 1/3 as active as codeine as an analgesic but it is an important intermediate in the production of hydrocodone, a painkiller about 3/4 the potency of morphine; as well as of oxycodone. The latter can also be synthesized from thebaine, however. (en) La codeinona es un opioide fuerte. Es un producto intermedio en la síntesis de algunos opioides semisintéticos, como la naloxona, naltrexona y la oxicodona. (es) La codéinone est un analgésique trois fois moins actif que la codéine ; mais c'est un produit intermédiaire important de la synthèse de l'hydrocodone, un analgésique possédant, comme l'oxycodone, 75 % de l'activité de la morphine. On peut synthétiser cette dernière à partir de thébaïne. On peut décrire la codéinone comme un méthyléther de la : 3-méthyl-morphinone, ou comme un dérivé cétonique de la codéine : codéine-6-one. (fr) |
| rdfs:label | Codeinone (en) Codeinona (es) Codéinone (fr) |
| owl:sameAs | freebase:Codeinone yago-res:Codeinone wikidata:Codeinone http://azb.dbpedia.org/resource/کودئینون dbpedia-es:Codeinone dbpedia-fa:Codeinone dbpedia-fr:Codeinone dbpedia-ro:Codeinone dbpedia-sh:Codeinone dbpedia-sr:Codeinone dbpedia-th:Codeinone https://global.dbpedia.org/id/4ZRBE |
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| is dbo:wikiPageWikiLink of | dbr:Sanguinarine dbr:Morphinone_reductase dbr:List_of_opioids dbr:Salutaridinol dbr:Morphine dbr:Alan_R._Battersby dbr:Codeinone_reductase_(NADPH) dbr:C18H19NO3 dbr:Opioid dbr:Oppenauer_oxidation dbr:Codeineone dbr:Carbonyl-codeine dbr:Carbonyl_codeine dbr:Carbonylcodeine |
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