Curli (original) (raw)
The Curli protein is a type of amyloid fiber produced by certain strains of enterobacteria. They are extracellular fibers located on bacteria such as E. coli and Salmonella spp. These fibers serve to promote cell community behavior through biofilm formation in the extracellular matrix. Amyloids are associated with several human neurodegenerative diseases such as Alzheimer's disease, Huntington's disease, Parkinson's disease, and prion diseases. The study of curli may help to understand human diseases thought to arise from improper amyloid fiber formation. The curli pili are generally assembled through the .
| Property | Value |
|---|---|
| dbo:abstract | The Curli protein is a type of amyloid fiber produced by certain strains of enterobacteria. They are extracellular fibers located on bacteria such as E. coli and Salmonella spp. These fibers serve to promote cell community behavior through biofilm formation in the extracellular matrix. Amyloids are associated with several human neurodegenerative diseases such as Alzheimer's disease, Huntington's disease, Parkinson's disease, and prion diseases. The study of curli may help to understand human diseases thought to arise from improper amyloid fiber formation. The curli pili are generally assembled through the . (en) La protéine Curli (ou curli) est un type de fibre amyloïde produite par certaines souches d'entérobactéries. Ce sont des fibrilles extracellulaires situées sur des bactéries telles que Escherichia coli et Salmonella sp. Ces fibrilles servent à promouvoir le comportement de la communauté cellulaire par la formation de biofilm dans la matrice extracellulaire. Cet amyloïde est associée à des maladies neurodégénératives humaines telles que la maladie d'Alzheimer ou le SLE. L'étude des curli peut aider à comprendre les maladies humaines qui pourraient résulter d'une mauvaise formation de fibres amyloïdes. Toutefois, chez E. coli, il s'agit d'une protéine purement fonctionnelle qui l'aide à s'accrocher aux protéines de l’hôte et à des surfaces inertes. (fr) |
| dbo:thumbnail | wiki-commons:Special:FilePath/3X2R.png?width=300 |
| dbo:wikiPageID | 56000338 (xsd:integer) |
| dbo:wikiPageLength | 14415 (xsd:nonNegativeInteger) |
| dbo:wikiPageRevisionID | 1089439546 (xsd:integer) |
| dbo:wikiPageWikiLink | dbr:Biofilm dbr:Beta_sheet dbr:Amyloid dbr:Pathogen-associated_molecular_pattern dbr:SDS-PAGE dbc:Bacterial_proteins dbr:Escherichia_coli dbr:Salmonella dbr:Enterobacteria dbr:Extracellular_matrix dbr:Pilus dbr:File:Probiotic-associated_therapeutic_curli_hybrids_(PATCH).pdf dbr:Extracellular_nucleation/precipitation_pathway |
| dbp:chromosome | Genomic (en) |
| dbp:entrezchromosome | NC_000913.3 (en) |
| dbp:entrezgene | 945619 (xsd:integer) |
| dbp:genlocEnd | 1101808 (xsd:integer) |
| dbp:genlocStart | 1100725 (xsd:integer) |
| dbp:name | Curli secretion channel (en) |
| dbp:organism | Escherichia coli , Salmonella spp. (en) |
| dbp:pdb | 3 (xsd:integer) |
| dbp:refseqmrna | NC_000913.3 (en) |
| dbp:refseqprotein | NP_415555.1 (en) |
| dbp:symbol | CsgG (en) |
| dbp:taxid | 83333 (xsd:integer) |
| dbp:uniprot | P0AEA2 (en) |
| dbp:wikiPageUsesTemplate | dbt:Cite_journal dbt:Infobox_nonhuman_protein dbt:Refbegin dbt:Refend dbt:Reflist dbt:Short_description |
| dcterms:subject | dbc:Bacterial_proteins |
| rdfs:comment | The Curli protein is a type of amyloid fiber produced by certain strains of enterobacteria. They are extracellular fibers located on bacteria such as E. coli and Salmonella spp. These fibers serve to promote cell community behavior through biofilm formation in the extracellular matrix. Amyloids are associated with several human neurodegenerative diseases such as Alzheimer's disease, Huntington's disease, Parkinson's disease, and prion diseases. The study of curli may help to understand human diseases thought to arise from improper amyloid fiber formation. The curli pili are generally assembled through the . (en) La protéine Curli (ou curli) est un type de fibre amyloïde produite par certaines souches d'entérobactéries. Ce sont des fibrilles extracellulaires situées sur des bactéries telles que Escherichia coli et Salmonella sp. Ces fibrilles servent à promouvoir le comportement de la communauté cellulaire par la formation de biofilm dans la matrice extracellulaire. Cet amyloïde est associée à des maladies neurodégénératives humaines telles que la maladie d'Alzheimer ou le SLE. L'étude des curli peut aider à comprendre les maladies humaines qui pourraient résulter d'une mauvaise formation de fibres amyloïdes. Toutefois, chez E. coli, il s'agit d'une protéine purement fonctionnelle qui l'aide à s'accrocher aux protéines de l’hôte et à des surfaces inertes. (fr) |
| rdfs:label | Curli (en) Curli (fr) |
| owl:sameAs | wikidata:Curli dbpedia-fr:Curli https://global.dbpedia.org/id/27HYM |
| prov:wasDerivedFrom | wikipedia-en:Curli?oldid=1089439546&ns=0 |
| foaf:depiction | wiki-commons:Special:FilePath/3X2R.png |
| foaf:isPrimaryTopicOf | wikipedia-en:Curli |
| is dbo:wikiPageWikiLink of | dbr:Curly dbr:Escherichia_coli_O157:H7 dbr:CsgD dbr:Curlee dbr:Curlee_(name) dbr:Curley dbr:Curley_(disambiguation) dbr:Curly_(disambiguation) dbr:Chaperone-usher_fimbriae dbr:RpoS dbr:Pilus |
| is foaf:primaryTopic of | wikipedia-en:Curli |
