Cyclazodone (original) (raw)

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dbo:abstract Cyclazodone is a centrally acting stimulant drug developed by American Cyanamid Company in the 1960s. The drug is related to other drugs such as pemoline and thozalinone. It displayed a favorable therapeutic index and margin of safety in comparison to Pemoline and other N-lower-alkyl-substituted Pemoline derivatives. The patents concluded that Cyclazodone possessed properties efficacious in reducing fatigue and as a potential anorectic. Structural congeners of Pemoline have been described as "excitants with unique properties distinguishing them from the sympathomimetic amines" whilst displaying less stimulatory activity and toxicity compared to amphetamine. It is included under the World Anti-Doping Agency prohibited list. (en) Циклазодон — стимулирующее вещество центрального действия, разработанное в 1960-ых годах. Должен был применяться для лечения СДВГ и хронической усталости. (ru)
dbo:casNumber 14461-91-7
dbo:chEMBL 2106536
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dbo:pubchem 26701
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dbp:routesOfAdministration Oral (en)
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rdfs:comment Циклазодон — стимулирующее вещество центрального действия, разработанное в 1960-ых годах. Должен был применяться для лечения СДВГ и хронической усталости. (ru) Cyclazodone is a centrally acting stimulant drug developed by American Cyanamid Company in the 1960s. The drug is related to other drugs such as pemoline and thozalinone. It displayed a favorable therapeutic index and margin of safety in comparison to Pemoline and other N-lower-alkyl-substituted Pemoline derivatives. The patents concluded that Cyclazodone possessed properties efficacious in reducing fatigue and as a potential anorectic. Structural congeners of Pemoline have been described as "excitants with unique properties distinguishing them from the sympathomimetic amines" whilst displaying less stimulatory activity and toxicity compared to amphetamine. (en)
rdfs:label Cyclazodone (en) Циклазодон (ru)
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