DMTMM (original) (raw)

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DMTMM (4-(4,6-dimethoxy-1,3,5-triazin-2-yl)-4-methyl-morpholinium chloride) is an organic triazine derivative commonly used for activation of carboxylic acids, particularly for amide synthesis. Amide coupling is one of the most common reactions in organic chemistry and DMTMM is one reagent used for that reaction. The mechanism of DMTMM coupling is similar to other common amide coupling reactions involving activated carboxylic acids. Its precursor, 2-chloro-4,6,-dimethoxy-1,3,5-triazine (CDMT), has also been used for amide coupling. DMTMM has also been used to synthesize other carboxylic functional groups such as esters and anhydrides. DMTMM is usually used in the chloride form but the tetrafluoroborate salt is also commercially available.

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dbo:abstract DMTMM (4-(4,6-dimethoxy-1,3,5-triazin-2-yl)-4-methyl-morpholinium chloride) is an organic triazine derivative commonly used for activation of carboxylic acids, particularly for amide synthesis. Amide coupling is one of the most common reactions in organic chemistry and DMTMM is one reagent used for that reaction. The mechanism of DMTMM coupling is similar to other common amide coupling reactions involving activated carboxylic acids. Its precursor, 2-chloro-4,6,-dimethoxy-1,3,5-triazine (CDMT), has also been used for amide coupling. DMTMM has also been used to synthesize other carboxylic functional groups such as esters and anhydrides. DMTMM is usually used in the chloride form but the tetrafluoroborate salt is also commercially available. (en)
dbo:alternativeName DMTMM, MMTM (en)
dbo:iupacName 4-(4,6-Dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholin-4-ium chloride (en)
dbo:thumbnail wiki-commons:Special:FilePath/DMTMM_2.svg?width=300
dbo:wikiPageID 54480612 (xsd:integer)
dbo:wikiPageLength 6519 (xsd:nonNegativeInteger)
dbo:wikiPageRevisionID 1124560168 (xsd:integer)
dbo:wikiPageWikiLink dbr:Hyaluronic_acid dbc:Chlorides dbc:Peptide_coupling_reagents dbc:Triazines dbr:Ester dbr:Organic_compound dbr:Organic_acid_anhydride dbr:N-Methylmorpholine dbr:Amide dbc:Morpholines dbr:Triazine dbr:File:DMTMM_Coupling_Reaction_Scheme.svg
dbp:imagecaption DMTMM Chemical Structure (en)
dbp:imagefile DMTMM 2.svg (en)
dbp:othernames DMTMM, MMTM (en)
dbp:pin 4 (xsd:integer)
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dct:subject dbc:Chlorides dbc:Peptide_coupling_reagents dbc:Triazines dbc:Morpholines
rdf:type owl:Thing dul:ChemicalObject dbo:ChemicalSubstance wikidata:Q11173 dbo:ChemicalCompound
rdfs:comment DMTMM (4-(4,6-dimethoxy-1,3,5-triazin-2-yl)-4-methyl-morpholinium chloride) is an organic triazine derivative commonly used for activation of carboxylic acids, particularly for amide synthesis. Amide coupling is one of the most common reactions in organic chemistry and DMTMM is one reagent used for that reaction. The mechanism of DMTMM coupling is similar to other common amide coupling reactions involving activated carboxylic acids. Its precursor, 2-chloro-4,6,-dimethoxy-1,3,5-triazine (CDMT), has also been used for amide coupling. DMTMM has also been used to synthesize other carboxylic functional groups such as esters and anhydrides. DMTMM is usually used in the chloride form but the tetrafluoroborate salt is also commercially available. (en)
rdfs:label DMTMM (en)
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