DNA walker (original) (raw)
A DNA walker is a class of nucleic acid nanomachines where a nucleic acid "walker" is able to move along a nucleic acid "track". The concept of a DNA walker was first defined and named by John H. Reif in 2003.A nonautonomous DNA walker requires external changes for each step, whereas an autonomous DNA walker progresses without any external changes. Various nonautonomous DNA walkers were developed, for example Shin controlled the motion of DNA walker by using 'control strands' which needed to be manually added in a specific order according to the template's sequence in order to get the desired path of motion.In 2004 the first autonomous DNA walker, which did not require external changes for each step, was experimentally demonstrated by the Reif group.
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| dbo:abstract | A DNA walker is a class of nucleic acid nanomachines where a nucleic acid "walker" is able to move along a nucleic acid "track". The concept of a DNA walker was first defined and named by John H. Reif in 2003.A nonautonomous DNA walker requires external changes for each step, whereas an autonomous DNA walker progresses without any external changes. Various nonautonomous DNA walkers were developed, for example Shin controlled the motion of DNA walker by using 'control strands' which needed to be manually added in a specific order according to the template's sequence in order to get the desired path of motion.In 2004 the first autonomous DNA walker, which did not require external changes for each step, was experimentally demonstrated by the Reif group. DNA walkers have functional properties such as a range of motion extending from linear to 2 and 3-dimensional, the ability to pick up and drop off molecular cargo, performing DNA-templated synthesis, and increased velocity of motion. DNA walkers have potential applications ranging from nanomedicine to nanorobotics. Many different fuel options have been studied including DNA hybridization, hydrolysis of DNA or ATP, and light. The DNA walker's function is similar to that of the proteins dynein and kinesin. (en) |
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| dbo:wikiPageWikiLink | dbr:Mutation dbr:DNA_machine dbr:DNA_nanotechnology dbr:Dynein dbr:Nucleic_acid dbr:Nucleic_acid_hybridization dbr:Nucleic_acid_templated_chemistry dbr:Complementarity_(molecular_biology) dbr:Nanomedicine dbr:Stator dbr:Heavy_metal_(chemical_element) dbr:Adenosine_triphosphate dbr:Kinesin dbr:Water_pollution dbr:RNA dbr:Restriction_enzyme dbc:Molecular_machines dbr:Hydrolysis dbc:DNA_nanotechnology dbr:DNA_nanotube dbr:Catenation dbr:Ribonuclease_H dbr:Nanorobotics dbr:Nucleoside_triphosphate dbr:T7_RNA_polymerase dbr:Double-stranded_DNA |
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| dcterms:subject | dbc:Molecular_machines dbc:DNA_nanotechnology |
| gold:hypernym | dbr:Nanomachines |
| rdfs:comment | A DNA walker is a class of nucleic acid nanomachines where a nucleic acid "walker" is able to move along a nucleic acid "track". The concept of a DNA walker was first defined and named by John H. Reif in 2003.A nonautonomous DNA walker requires external changes for each step, whereas an autonomous DNA walker progresses without any external changes. Various nonautonomous DNA walkers were developed, for example Shin controlled the motion of DNA walker by using 'control strands' which needed to be manually added in a specific order according to the template's sequence in order to get the desired path of motion.In 2004 the first autonomous DNA walker, which did not require external changes for each step, was experimentally demonstrated by the Reif group. (en) |
| rdfs:label | DNA walker (en) |
| owl:sameAs | yago-res:DNA walker wikidata:DNA walker https://global.dbpedia.org/id/2PUWC |
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