| dbo:abstract |
ديميكلوسيكلين (بالإنجليزية: Demeclocycline) هو دواء يُستعمل في علاج: * حب الشباب * متلازمة الإفراز غير الملائم للهرمون المضاد لإدرار البول * مرض السيلان * عدوى الجهاز البولي * سعال ديكي * خمج جرثومي (ar) Demeclocyclin ist ein Arzneistoff aus der Gruppe der Antibiotika. Zudem hat Demeclocyclin eine harntreibende Wirkung. (de) Demeclocycline (INN, BAN, USAN, brand name Declomycin) is a tetracycline antibiotic which was derived from a mutant strain of Streptomyces aureofaciens. (en) La déméclocycline vendue sous le nom commercial Ledermycine puis Alkanotrem est une tétracycline. C'est à l'origine un antibiotique dérivé de Streptomyces aureofaciens. Elle est utilisée dans le traitement symptomatique des sécrétions inappropriées d'hormone antidiurétique notamment d'origine néoplasique. En 2006, il n'y a pas d'autres traitements ayant une AMM dans cette indication. Le service médical rendu (SMR) est important.L'amélioration du service médical rendu (ASMR) est de II. (fr) Demeclociclina (Declomycin, Declostatin y Ledermycin) es una tetraciclina derivada de una cepa de . (es) La demeclociclina è un antibiotico tetraciclinico, ad azione batteriostatica, isolato da un ceppo mutante di Streptomyces aureofaciens. In Italia è stato venduta fino al 1988 dalla società farmaceutica con il nome commerciale di Ledermicina nella forma farmaceutica di compresse contenenti 300 mg di principio attivo. (it) 地美环素（INN，和名称：Demeclocycline），又名去甲基金霉素或脱甲金霉素，是衍变自突变菌株的四环素类抗生素。 (zh) |
| dbo:alternativeName |
Declomycin (en) |
| dbo:bioavailability |
60.000000 (xsd:float) |
| dbo:casNumber |
(HCl) 127-33-3 |
| dbo:chEBI |
4392 |
| dbo:chEMBL |
1591 |
| dbo:drugbank |
DB00618 |
| dbo:fdaUniiCode |
5R5W9ICI6O |
| dbo:kegg |
D03680 |
| dbo:medlinePlus |
a682103 |
| dbo:pubchem |
54680690 |
| dbo:thumbnail |
wiki-commons:Special:FilePath/Demeclocycline.svg?width=300 |
| dbo:wikiPageID |
1347323 (xsd:integer) |
| dbo:wikiPageLength |
12425 (xsd:nonNegativeInteger) |
| dbo:wikiPageRevisionID |
1098230571 (xsd:integer) |
| dbo:wikiPageWikiLink |
dbr:Calcium dbr:Vasopressin_receptor_antagonist dbr:Bone dbr:Antacid dbr:Hyponatremia dbr:Lithium_(medication) dbr:Lithium_carbonate dbr:Arginine_vasopressin_receptor_2 dbr:Renal_function dbr:List_of_psychotropic_medications dbc:Chloroarenes dbc:Triketones dbr:Protein_synthesis dbr:Liver dbr:Lyme_disease dbr:Magnesium dbc:Tetracycline_antibiotics dbr:Streptomyces_aureofaciens dbr:Bacteria dbr:Bronchitis dbr:Adenylyl_cyclase dbr:Cation dbr:Tolvaptan dbr:Acne_vulgaris dbc:Carboxamides dbr:British_Approved_Name dbr:Tooth dbr:International_Nonproprietary_Name dbr:Intracellular dbr:Iron dbr:Hydrochloride dbc:Drugs_with_unknown_mechanisms_of_action dbc:Nephrotoxins dbr:Kidney dbr:Tetracycline_antibiotics dbr:Diabetes_insipidus dbr:30S dbr:Sodium dbr:Infection dbr:United_States_Adopted_Name dbr:Off-label_use dbr:Bacteriostatic dbr:Syndrome_of_inappropriate_antidiuretic_hormone dbr:File:Demeclocycline_3D.png dbr:Tetracycline_antibiotic dbr:Second_messenger_cascade dbr:Antidiuretic_hormone dbr:File:Demeclocycline.svg |
| dbp:atcPrefix |
D06 (en) |
| dbp:atcSuffix |
AA01 (en) |
| dbp:bioavailability |
60 (xsd:integer) |
| dbp:c |
21 (xsd:integer) |
| dbp:casNumber |
127 (xsd:integer) |
| dbp:chebi |
4392 (xsd:integer) |
| dbp:chembl |
1591 (xsd:integer) |
| dbp:chemspiderid |
10482117 (xsd:integer) |
| dbp:cl |
1 (xsd:integer) |
| dbp:drugbank |
DB00618 (en) |
| dbp:eliminationHalfLife |
-61200.0 |
| dbp:excretion |
dbr:Kidney |
| dbp:h |
21 (xsd:integer) |
| dbp:image |
dbr:File:Demeclocycline_3D.png |
| dbp:iupacName |
-2 (xsd:integer) |
| dbp:kegg |
D03680 (en) |
| dbp:legalStatus |
Rx-only (en) |
| dbp:medlineplus |
a682103 (en) |
| dbp:metabolism |
dbr:Liver |
| dbp:n |
2 (xsd:integer) |
| dbp:o |
8 (xsd:integer) |
| dbp:pregnancyUs |
D (en) |
| dbp:proteinBound |
41 (xsd:integer) |
| dbp:pubchem |
54680690 (xsd:integer) |
| dbp:routesOfAdministration |
Oral (en) |
| dbp:smiles |
NCC1C[C@@]2C=C3Cc4ccccc4[C@@H][C@H]3C[C@H]2CNC (en) |
| dbp:stdinchi |
1 (xsd:integer) |
| dbp:stdinchikey |
FMTDIUIBLCQGJB-SEYHBJAFSA-N (en) |
| dbp:synonyms |
RP-10192, demethylchlortetracycline (en) |
| dbp:tradename |
Declomycin (en) |
| dbp:unii |
5 (xsd:integer) |
| dbp:verifiedrevid |
460775334 (xsd:integer) |
| dbp:wikiPageUsesTemplate |
dbt:Diuretics dbt:Antibiotics_and_chemotherapeutics_for_dermatological_use dbt:CAS dbt:Drugbox dbt:Fact dbt:Reflist dbt:Cascite dbt:Chemspidercite dbt:Drugbankcite dbt:Ebicite dbt:Fdacite dbt:Keggcite dbt:Stdinchicite dbt:TetracyclineAntiBiotics dbt:ATC dbt:Drugs.com dbt:Oxytocin_and_vasopressin_receptor_modulators |
| dcterms:subject |
dbc:Chloroarenes dbc:Triketones dbc:Tetracycline_antibiotics dbc:Carboxamides dbc:Drugs_with_unknown_mechanisms_of_action dbc:Nephrotoxins |
| rdf:type |
owl:Thing dul:ChemicalObject dbo:ChemicalSubstance wikidata:Q8386 yago:WikicatAmides yago:Abstraction100002137 yago:Amide114724264 yago:Chemical114806838 yago:Compound114818238 yago:Material114580897 yago:Matter100020827 yago:OrganicCompound114727670 yago:Part113809207 yago:PhysicalEntity100001930 yago:Relation100031921 dbo:Drug yago:Substance100019613 umbel-rc:DrugProduct |
| rdfs:comment |
ديميكلوسيكلين (بالإنجليزية: Demeclocycline) هو دواء يُستعمل في علاج: * حب الشباب * متلازمة الإفراز غير الملائم للهرمون المضاد لإدرار البول * مرض السيلان * عدوى الجهاز البولي * سعال ديكي * خمج جرثومي (ar) Demeclocyclin ist ein Arzneistoff aus der Gruppe der Antibiotika. Zudem hat Demeclocyclin eine harntreibende Wirkung. (de) Demeclocycline (INN, BAN, USAN, brand name Declomycin) is a tetracycline antibiotic which was derived from a mutant strain of Streptomyces aureofaciens. (en) La déméclocycline vendue sous le nom commercial Ledermycine puis Alkanotrem est une tétracycline. C'est à l'origine un antibiotique dérivé de Streptomyces aureofaciens. Elle est utilisée dans le traitement symptomatique des sécrétions inappropriées d'hormone antidiurétique notamment d'origine néoplasique. En 2006, il n'y a pas d'autres traitements ayant une AMM dans cette indication. Le service médical rendu (SMR) est important.L'amélioration du service médical rendu (ASMR) est de II. (fr) Demeclociclina (Declomycin, Declostatin y Ledermycin) es una tetraciclina derivada de una cepa de . (es) La demeclociclina è un antibiotico tetraciclinico, ad azione batteriostatica, isolato da un ceppo mutante di Streptomyces aureofaciens. In Italia è stato venduta fino al 1988 dalla società farmaceutica con il nome commerciale di Ledermicina nella forma farmaceutica di compresse contenenti 300 mg di principio attivo. (it) 地美环素（INN，和名称：Demeclocycline），又名去甲基金霉素或脱甲金霉素，是衍变自突变菌株的四环素类抗生素。 (zh) |
| rdfs:label |
ديميكلوسيكلين (ar) Demeclocyclin (de) Demeclociclina (es) Demeclocycline (en) Déméclocycline (fr) Demeclociclina (it) 地美环素 (zh) |
| owl:sameAs |
freebase:Demeclocycline wikidata:Demeclocycline wikidata:Demeclocycline dbpedia-ar:Demeclocycline http://azb.dbpedia.org/resource/ديميكلوسيكلين dbpedia-cy:Demeclocycline dbpedia-de:Demeclocycline dbpedia-es:Demeclocycline dbpedia-fa:Demeclocycline dbpedia-fi:Demeclocycline dbpedia-fr:Demeclocycline dbpedia-it:Demeclocycline dbpedia-ro:Demeclocycline dbpedia-sh:Demeclocycline dbpedia-sr:Demeclocycline dbpedia-th:Demeclocycline dbpedia-tr:Demeclocycline dbpedia-zh:Demeclocycline https://global.dbpedia.org/id/2Z3Ug http://www4.wiwiss.fu-berlin.de/drugbank/resource/drugs/DB00618 yago-res:Demeclocycline |
| prov:wasDerivedFrom |
wikipedia-en:Demeclocycline?oldid=1098230571&ns=0 |
| foaf:depiction |
wiki-commons:Special:FilePath/Demeclocycline.svg wiki-commons:Special:FilePath/Demeclocycline_3D.png |
| foaf:isPrimaryTopicOf |
wikipedia-en:Demeclocycline |
| is dbo:wikiPageRedirects of |
dbr:Elkamicina dbr:Novotriclina dbr:Perciclina dbr:Clortetrin dbr:Declomycin dbr:Declostatin dbr:C21H21ClN2O8 dbr:DMCT dbr:Bioterciclin dbr:Deganol dbr:Demeclor dbr:Demethylchlortetracyclin dbr:Demetraclin dbr:ATC_code_D06AA01 dbr:ATC_code_J01AA01 dbr:ATCvet_code_QD06AA01 dbr:ATCvet_code_QJ01AA01 dbr:Mexocine dbr:Diuciclin dbr:Methylchlorotetracycline dbr:Ledermycin dbr:Sumaclina dbr:Demeclocycline_Hydrochloride dbr:Demeclocycline_hydrochloride |
| is dbo:wikiPageWikiLink of |
dbr:List_of_antibiotics dbr:Vasopressin_receptor_antagonist dbr:Primary_polydipsia dbr:Aquaretic dbr:Hyponatremia dbr:Vasopressin dbr:Elkamicina dbr:Novotriclina dbr:Perciclina dbr:Timeline_of_antibiotics dbr:Clortetrin dbr:Declomycin dbr:Declostatin dbr:C21H21ClN2O8 dbr:DMCT dbr:Bioterciclin dbr:Deganol dbr:Demeclor dbr:Demethylchlortetracyclin dbr:Demetraclin dbr:List_of_MeSH_codes_(D04) dbr:ATC_code_D06AA01 dbr:ATC_code_J01AA01 dbr:ATCvet_code_QD06AA01 dbr:ATCvet_code_QJ01AA01 dbr:Hypotonic_hyponatremia dbr:Mexocine dbr:ATC_code_D06 dbr:ATC_code_J01 dbr:Syndrome_of_inappropriate_antidiuretic_hormone_secretion dbr:Tetracycline_antibiotics dbr:Mechanism_of_action dbr:Nephrotoxicity dbr:Diuciclin dbr:Vasopressin_receptor_2 dbr:List_of_drugs:_De dbr:Methylchlorotetracycline dbr:Ledermycin dbr:Sumaclina dbr:Demeclocycline_Hydrochloride dbr:Demeclocycline_hydrochloride |
| is foaf:primaryTopic of |
wikipedia-en:Demeclocycline |
