| dbo:abstract |
Digoxin immune fab or digoxin-specific antibody is an antidote for overdose of digoxin. It is made from immunoglobulin fragments from sheep that have already been immunized with a digoxin derivative, (DDMA). Its brand names include Digibind (GlaxoSmithKline) and DigiFab (BTG plc). (en) Digitalis-Antidot, auch Digitalis-Antitoxin, ist ein medizinisches „Gegenmittel“ (griech. Antidot) oder „Gegengift“ (griech. Antitoxin) bei einer lebensbedrohlichen Digitalisintoxikation (Digitalisvergiftung), die durch überhöhte Einnahme von Digoxin, Digitoxin oder anderen Digoxin-Derivaten auftreten kann. Diese Stoffe werden nachfolgend auch „Digitalisglykoside“ oder kurz „Glykoside“ genannt. (de) Los anticuerpos anti-digoxina son fragmentos de inmunoglobulinas de oveja a la que se ha sensibilizado para producir anticuerpos. (es) Digitalis-Antidot – związek organiczny wykorzystywany jako antidotum w zatruciu glikozydami naparstnicy. Lek jest pozyskiwany z przeciwciał owiec domowych wcześniej immunizowanych pochodną digoksyny – . Lek jest produkowany pod nazwami Digibind (przez GlaxoSmithKline) i DigiFab (przez BTG plc). (pl) |
| dbo:alternativeName |
Digibind, others (en) |
| dbo:chEMBL |
1201588 |
| dbo:drugbank |
DB00076 |
| dbo:thumbnail |
wiki-commons:Special:FilePath/Digibind.jpg?width=300 |
| dbo:wikiPageExternalLink |
https://www.drugs.com/cdi/digibind.html https://web.archive.org/web/20071005002208/http:/www.rxlist.com/cgi/generic/digoxinfab.htm |
| dbo:wikiPageID |
12637519 (xsd:integer) |
| dbo:wikiPageLength |
9573 (xsd:nonNegativeInteger) |
| dbo:wikiPageRevisionID |
1112182153 (xsd:integer) |
| dbo:wikiPageWikiLink |
dbr:Cardiac_arrhythmia dbr:Hypokalemia dbc:Antitoxins dbr:GlaxoSmithKline dbr:Antibody dbr:Anaphylactic_shock dbr:Papain dbr:Bromelain dbr:Papaya dbr:Digitalis dbr:Digoxin_toxicity dbr:Kidney dbr:IV_infusion dbr:Digoxin dbr:Arrhythmia dbr:Injection_(medicine) dbr:Sheep dbr:Blood_serum dbr:Digoxindicarboxymethoxylamine |
| dbp:atcPrefix |
V03 (en) |
| dbp:atcSuffix |
AB24 (en) |
| dbp:c |
2085 (xsd:integer) |
| dbp:caption |
Bottle of digoxin immune fab (en) |
| dbp:chembl |
1201588 (xsd:integer) |
| dbp:chemspiderid |
none (en) |
| dbp:drugbank |
DB00076 (en) |
| dbp:durationOfAction |
72000.0 (dbd:second) |
| dbp:eliminationHalfLife |
82800.0 (dbd:second) |
| dbp:excretion |
dbr:Kidney |
| dbp:h |
3223 (xsd:integer) |
| dbp:iupacName |
Anti-digoxin antibody fragment (en) |
| dbp:n |
553 (xsd:integer) |
| dbp:o |
672 (xsd:integer) |
| dbp:onset |
1800.0 (dbd:second) |
| dbp:pregnancyUs |
C (en) |
| dbp:routesOfAdministration |
dbr:IV_infusion dbr:Injection_(medicine) |
| dbp:s |
16 (xsd:integer) |
| dbp:tradename |
Digibind, others (en) |
| dbp:verifiedfields |
changed (en) |
| dbp:verifiedrevid |
476992171 (xsd:integer) |
| dbp:wikiPageUsesTemplate |
dbt:Antidotes dbt:Cn dbt:Drugbox dbt:Reflist dbt:Unreferenced_section dbt:Chemspidercite dbt:Drugbankcite dbt:Ebicite dbt:Drugs.com |
| dct:subject |
dbc:Antitoxins |
| gold:hypernym |
dbr:Antidote |
| rdf:type |
owl:Thing dul:ChemicalObject dbo:ChemicalSubstance wikidata:Q8386 yago:WikicatAntibodies yago:WikicatAntitoxins yago:Abstraction100002137 yago:Antibody115027189 yago:Antitoxin115028050 yago:Chemical114806838 yago:Compound114818238 yago:LanguageUnit106284225 yago:Macromolecule114944888 yago:Material114580897 yago:Matter100020827 yago:Molecule114682133 yago:Name106333653 yago:OrganicCompound114727670 yago:Part113809207 yago:PhysicalEntity100001930 yago:Protein114728724 yago:Relation100031921 yago:WikicatGlaxoSmithKlineBrands dbo:Drug yago:Substance100019613 yago:Thing100002452 yago:TradeName106845599 yago:Unit109465459 umbel-rc:DrugProduct |
| rdfs:comment |
Digoxin immune fab or digoxin-specific antibody is an antidote for overdose of digoxin. It is made from immunoglobulin fragments from sheep that have already been immunized with a digoxin derivative, (DDMA). Its brand names include Digibind (GlaxoSmithKline) and DigiFab (BTG plc). (en) Digitalis-Antidot, auch Digitalis-Antitoxin, ist ein medizinisches „Gegenmittel“ (griech. Antidot) oder „Gegengift“ (griech. Antitoxin) bei einer lebensbedrohlichen Digitalisintoxikation (Digitalisvergiftung), die durch überhöhte Einnahme von Digoxin, Digitoxin oder anderen Digoxin-Derivaten auftreten kann. Diese Stoffe werden nachfolgend auch „Digitalisglykoside“ oder kurz „Glykoside“ genannt. (de) Los anticuerpos anti-digoxina son fragmentos de inmunoglobulinas de oveja a la que se ha sensibilizado para producir anticuerpos. (es) Digitalis-Antidot – związek organiczny wykorzystywany jako antidotum w zatruciu glikozydami naparstnicy. Lek jest pozyskiwany z przeciwciał owiec domowych wcześniej immunizowanych pochodną digoksyny – . Lek jest produkowany pod nazwami Digibind (przez GlaxoSmithKline) i DigiFab (przez BTG plc). (pl) |
| rdfs:label |
Digitalis-Antidot (de) Digoxin immune fab (en) Anticuerpos antidigoxina (es) Digitalis-Antidot (pl) |
| owl:sameAs |
freebase:Digoxin immune fab http://www4.wiwiss.fu-berlin.de/drugbank/resource/drugs/DB00076 yago-res:Digoxin immune fab wikidata:Digoxin immune fab dbpedia-de:Digoxin immune fab dbpedia-es:Digoxin immune fab dbpedia-pl:Digoxin immune fab dbpedia-sh:Digoxin immune fab dbpedia-sr:Digoxin immune fab https://global.dbpedia.org/id/53mp2 |
| prov:wasDerivedFrom |
wikipedia-en:Digoxin_immune_fab?oldid=1112182153&ns=0 |
| foaf:depiction |
wiki-commons:Special:FilePath/Digibind.jpg |
| foaf:isPrimaryTopicOf |
wikipedia-en:Digoxin_immune_fab |
| is dbo:wikiPageRedirects of |
dbr:ATC_code_V03AB24 dbr:ATCvet_code_QV03AB24 dbr:DigiFab dbr:Digoxin_Immune_Fab dbr:Digoxin_immune_Fab dbr:Digoxin-specific_antibody_fragments dbr:Digibind dbr:Digitalis_antitoxin |
| is dbo:wikiPageWikiLink of |
dbr:Digoxin_toxicity dbr:Fragment_antigen-binding dbr:ATC_code_V03AB24 dbr:ATCvet_code_QV03AB24 dbr:Cascabela_thevetia dbr:DigiFab dbr:Digoxin_Immune_Fab dbr:Digoxin_immune_Fab dbr:Digoxin-specific_antibody_fragments dbr:Digibind dbr:Digitalis_antitoxin |
| is foaf:primaryTopic of |
wikipedia-en:Digoxin_immune_fab |
