Dimethisterone (original) (raw)

dbo:abstract

Dimethisterone, formerly sold under the brand names Lutagan and Secrosteron among others, is a progestin medication which was used in birth control pills and in the treatment of gynecological disorders but is now no longer available. It was used both alone and in combination with an estrogen. It is taken by mouth. Side effects of dimethisterone are similar to those of other progestins. When used in combination with high doses of an estrogen, an increased risk of endometrial cancer can occur. Dimethisterone is a progestin, or a synthetic progestogen, and hence is an agonist of the progesterone receptor, the biological target of progestogens like progesterone. It has some antimineralocorticoid activity and no other important hormonal activity. Dimethisterone was first described and was introduced for medical use in 1959. It started being used in birth control pills in 1965. However, due to its low potency and consequent inability to prevent the increased risk of endometrial cancer with estrogens, dimethisterone was soon discontinued for such purposes. (en)
二甲炔酮，也译作地美炔酮（英語：Dimethisterone，商品名：Lutagan 或 Secrosteron等）是一种黄体制剂药物，过去被用于治疗一些妇科疾病以及作为避孕药，但现在已不再使用。 (zh)

dbo:alternativeName

Lutagan, Secrosteron, others (en)

dbo:casNumber

79-64-1

dbo:class

dbo:fdaUniiCode

OIC9M646C5

dbo:pubchem

6607

dbo:thumbnail

wiki-commons:Special:FilePath/Dimethisterone.svg?width=300

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23484571 (xsd:integer)

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14954 (xsd:nonNegativeInteger)

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1123032489 (xsd:integer)

dbo:wikiPageWikiLink

dbp:alt

Skeletal formula of dimethisterone (en)
Ball-and-stick model of the dimethisterone molecule (en)

dbp:c

23 (xsd:integer)

dbp:casNumber

79 (xsd:integer)

dbp:chemspiderid

6357 (xsd:integer)

dbp:class

dbp:h

32 (xsd:integer)

dbp:image

Dimethisterone 3D ball.png (en)

dbp:iupacName

-17 (xsd:integer)

dbp:o

2 (xsd:integer)

dbp:pubchem

6607 (xsd:integer)

dbp:routesOfAdministration

dbr:Oral_administration

dbp:smiles

CC#C[C@@]1O (en)

dbp:stdinchi

1 (xsd:integer)

dbp:stdinchikey

LVHOURKCKUYIGK-RGUJTQARSA-N (en)

dbp:synonyms

Dimethindrone; 6α,21-Dimethylethisterone; 6α,21-Dimethyl-17α-ethynyltestosterone; 17α-Ethynyl-6α,21-dimethylandrost-4-en-17β-ol-3-one; 6α,21-Dimethyl-17β-hydroxy-17α-pregn-4-en-20-yn-3-one (en)

dbp:tradename

Lutagan, Secrosteron, others (en)

dbp:unii

OIC9M646C5 (en)

dbp:width

225 (xsd:integer)

dbp:wikiPageUsesTemplate

dct:subject

gold:hypernym

dbr:Progestin

rdf:type

rdfs:comment

二甲炔酮，也译作地美炔酮（英語：Dimethisterone，商品名：Lutagan 或 Secrosteron等）是一种黄体制剂药物，过去被用于治疗一些妇科疾病以及作为避孕药，但现在已不再使用。 (zh)
Dimethisterone, formerly sold under the brand names Lutagan and Secrosteron among others, is a progestin medication which was used in birth control pills and in the treatment of gynecological disorders but is now no longer available. It was used both alone and in combination with an estrogen. It is taken by mouth. (en)

rdfs:label

Dimethisterone (en)
二甲炔酮 (zh)

rdfs:seeAlso

owl:sameAs

prov:wasDerivedFrom

wikipedia-en:Dimethisterone?oldid=1123032489&ns=0

foaf:depiction

foaf:isPrimaryTopicOf

wikipedia-en:Dimethisterone

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wikipedia-en:Dimethisterone