DinG RNA motif (original) (raw)
The dinG RNA motif is a conserved RNA structure that was discovered by bioinformatics. dinG motifs are found in Clostridiales. It is ambiguous whether dinG RNAs function as cis-regulatory elements or whether they operate in trans. Arguing in favor of cis regulation is the fact that the dinG RNAs exist upstream of protein-coding genes. However, in several cases, the dinG RNAs are more than 1 kilobase away from the gene's start codon, which is an unusually long distance for a cis-regulatory element. It was noted that all of these cases with long distances occur in metagenomic sequences, and therefore might relate to problems with sequence assembly rather than biological sequences.
| Property | Value |
|---|---|
| dbo:abstract | The dinG RNA motif is a conserved RNA structure that was discovered by bioinformatics. dinG motifs are found in Clostridiales. It is ambiguous whether dinG RNAs function as cis-regulatory elements or whether they operate in trans. Arguing in favor of cis regulation is the fact that the dinG RNAs exist upstream of protein-coding genes. However, in several cases, the dinG RNAs are more than 1 kilobase away from the gene's start codon, which is an unusually long distance for a cis-regulatory element. It was noted that all of these cases with long distances occur in metagenomic sequences, and therefore might relate to problems with sequence assembly rather than biological sequences. The genes downstream of dinG RNAs are usually predicted to function as helicases, or similar activities. Thus, if dinG RNAs are cis-regulatory elements, they presumably regulate some process related to helicases. (en) |
| dbo:thumbnail | wiki-commons:Special:FilePath/RF03082.svg?width=300 |
| dbo:wikiPageID | 58095179 (xsd:integer) |
| dbo:wikiPageLength | 2065 (xsd:nonNegativeInteger) |
| dbo:wikiPageRevisionID | 1059163871 (xsd:integer) |
| dbo:wikiPageWikiLink | dbr:Clostridiales dbr:Gene dbc:Non-coding_RNA dbr:Codon dbr:Helicase dbr:RNA dbr:Bioinformatics_discovery_of_non-coding_RNAs dbr:Cis-regulatory_element dbr:Metagenomic dbr:Sequence_conservation dbr:Small_RNA dbr:Secondary_structure |
| dbp:caption | Consensus secondary structure and sequence conservation of dinG RNA (en) |
| dbp:name | dinG (en) |
| dbp:rfam | RF03082 (en) |
| dbp:rnaType | dbr:Gene dbr:Small_RNA |
| dbp:symbol | dinG (en) |
| dbp:wikiPageUsesTemplate | dbt:Multiple_issues dbt:Orphan dbt:Primary_sources dbt:Reflist dbt:SO dbt:Infobox_rfam |
| dct:subject | dbc:Non-coding_RNA |
| rdfs:comment | The dinG RNA motif is a conserved RNA structure that was discovered by bioinformatics. dinG motifs are found in Clostridiales. It is ambiguous whether dinG RNAs function as cis-regulatory elements or whether they operate in trans. Arguing in favor of cis regulation is the fact that the dinG RNAs exist upstream of protein-coding genes. However, in several cases, the dinG RNAs are more than 1 kilobase away from the gene's start codon, which is an unusually long distance for a cis-regulatory element. It was noted that all of these cases with long distances occur in metagenomic sequences, and therefore might relate to problems with sequence assembly rather than biological sequences. (en) |
| rdfs:label | DinG RNA motif (en) |
| owl:sameAs | wikidata:DinG RNA motif https://global.dbpedia.org/id/6bQ1k |
| prov:wasDerivedFrom | wikipedia-en:DinG_RNA_motif?oldid=1059163871&ns=0 |
| foaf:depiction | wiki-commons:Special:FilePath/RF03082.svg |
| foaf:isPrimaryTopicOf | wikipedia-en:DinG_RNA_motif |
| is foaf:primaryTopic of | wikipedia-en:DinG_RNA_motif |
