ENDIA (original) (raw)
The Environmental Determinants of Islet Autoimmunity (ENDIA) Study is an Australian prospective pregnancy cohort study investigating the environmental triggers responsible for the autoimmune process that leads to type 1 diabetes. The study is led by Professor Jennifer Couper from the University of Adelaide in South Australia with collaborators from the Walter and Eliza Hall Institute, Royal Melbourne Hospital, Monash University and Monash Medical Centre in Victoria, the University of NSW and the Children's Hospital at Westmead, the Royal Hospital for Women and St. George's Hospital in NSW, the University of Queensland and Mater Health Services in Queensland, and the University of Western Australia and Princess Margaret Hospital for Children in Western Australia.
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| dbo:abstract | The Environmental Determinants of Islet Autoimmunity (ENDIA) Study is an Australian prospective pregnancy cohort study investigating the environmental triggers responsible for the autoimmune process that leads to type 1 diabetes. The study is led by Professor Jennifer Couper from the University of Adelaide in South Australia with collaborators from the Walter and Eliza Hall Institute, Royal Melbourne Hospital, Monash University and Monash Medical Centre in Victoria, the University of NSW and the Children's Hospital at Westmead, the Royal Hospital for Women and St. George's Hospital in NSW, the University of Queensland and Mater Health Services in Queensland, and the University of Western Australia and Princess Margaret Hospital for Children in Western Australia. The aim of the ENDIA Study is to identify environmental factors and gene-environment interactions that contribute to and protect against the development of islet autoimmunity and progression to type 1 diabetes in children genetically at-risk. The study will follow 1,400 infants with a first-degree relative with type 1 diabetes prospectively from early pregnancy into childhood to investigate relationships between prenatal and postnatal environmental factors, and the development of islet autoimmunity and subsequent type 1 diabetes. ENDIA will evaluate the microbiome, nutrition, bodyweight/composition, metabolome-lipidome, insulin resistance, innate and adaptive immune function and viral infections. A systems biology approach will integrate multi-omics analyses to explore hypotheses and mechanisms underlying the development of islet autoimmunity. The protocol for the ENDIA Study was published in BMC Pediatrics in 2013. (en) |
| dbo:wikiPageExternalLink | http://www.endia.org.au |
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| dbo:wikiPageRevisionID | 960007158 (xsd:integer) |
| dbo:wikiPageWikiLink | dbr:Princess_Margaret_Hospital_for_Children dbr:Royal_Hospital_for_Women dbr:Royal_Melbourne_Hospital dbr:Metabolome dbr:University_of_Adelaide dbr:University_of_Queensland dbr:University_of_Western_Australia dbr:Insulin_resistance dbr:Monash_Medical_Centre dbr:Monash_University dbr:The_Leona_M._and_Harry_B._Helmsley_Charitable_Trust dbc:Research_in_Australia dbr:Type_1_diabetes dbr:JDRF dbc:Diabetes dbr:Systems_biology dbr:Microbiome dbr:National_Health_and_Medical_Research_Council dbr:Mater_Health_Services dbr:Walter_and_Eliza_Hall_Institute dbr:University_of_NSW dbr:Children's_Hospital_at_Westmead dbr:File:Logo_of_the_ENDIA_study.tif |
| dbp:above | Environmental Determinants of Islet Autoimmunity Study (en) |
| dbp:abovestyle | background:#cfc; (en) |
| dbp:below | http://www.endia.org.au |
| dbp:belowstyle | background:#ddf; (en) |
| dbp:data | 1400 (xsd:integer) dbr:University_of_Adelaide 1.57788E7 (dbd:second) Professor Jennifer Couper (en) SA, WA, NSW, Vic, QLD (en) |
| dbp:header | ENDIA Study summary (en) |
| dbp:headerstyle | background:#ccf; (en) |
| dbp:label | Principal Investigator (en) Administering Institution (en) Eligibility criteria (en) Participating states (en) Recruitment target (en) |
| dbp:labelstyle | background:#ddf; (en) |
| dbp:name | ENDIA Study (en) |
| dbp:wikiPageUsesTemplate | dbt:Infobox dbt:Orphan dbt:Primary_sources dbt:Reflist |
| dct:subject | dbc:Research_in_Australia dbc:Diabetes |
| gold:hypernym | dbr:Study |
| rdf:type | dbo:Book |
| rdfs:comment | The Environmental Determinants of Islet Autoimmunity (ENDIA) Study is an Australian prospective pregnancy cohort study investigating the environmental triggers responsible for the autoimmune process that leads to type 1 diabetes. The study is led by Professor Jennifer Couper from the University of Adelaide in South Australia with collaborators from the Walter and Eliza Hall Institute, Royal Melbourne Hospital, Monash University and Monash Medical Centre in Victoria, the University of NSW and the Children's Hospital at Westmead, the Royal Hospital for Women and St. George's Hospital in NSW, the University of Queensland and Mater Health Services in Queensland, and the University of Western Australia and Princess Margaret Hospital for Children in Western Australia. (en) |
| rdfs:label | ENDIA (en) |
| owl:sameAs | freebase:ENDIA wikidata:ENDIA https://global.dbpedia.org/id/fsc8 |
| prov:wasDerivedFrom | wikipedia-en:ENDIA?oldid=960007158&ns=0 |
| foaf:homepage | http://www.endia.org.au |
| foaf:isPrimaryTopicOf | wikipedia-en:ENDIA |
| is foaf:primaryTopic of | wikipedia-en:ENDIA |