Ed Harlow (original) (raw)
Edward Everett Harlow (* 1952) ist ein US-amerikanischer Molekularbiologe, Genetiker und Onkologe. Harlow erwarb einen Bachelor und einen Master an der University of Oklahoma in Norman, Oklahoma und einen Ph.D. am Imperial Cancer Research Fund in London. 2009 übernahm Harlow die Funktion des Chief Scientific Officer (CSO) bei der Firma Constellation Pharmaceuticals in Cambridge, Massachusetts.
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| dbo:abstract | Edward Everett Harlow (* 1952) ist ein US-amerikanischer Molekularbiologe, Genetiker und Onkologe. Harlow erwarb einen Bachelor und einen Master an der University of Oklahoma in Norman, Oklahoma und einen Ph.D. am Imperial Cancer Research Fund in London. Harlow hatte eine Professur für Biochemie und molekulare Pharmakologie an der Harvard Medical School und war Associate Director des Dana-Farber Cancer Institute, beide Institutionen haben ihren Sitz in Boston, Massachusetts. Davor war er wissenschaftlicher Direktor am Massachusetts General Hospital Cancer Center, ebenfalls in Boston, und am National Cancer Institute. 2009 übernahm Harlow die Funktion des Chief Scientific Officer (CSO) bei der Firma Constellation Pharmaceuticals in Cambridge, Massachusetts. Harlow hat – zum Teil aufbauend auf die Arbeiten von Arnold J. Levine – grundlegende Erkenntnisse zur Interaktion zwischen Onkogenen und einerseits und anderen zellulären Eiweißen andererseits beigetragen. Er hat die Interaktion zwischen dem Genprodukt des Retinoblastom-Gens – dem Retinoblastom-Protein – und viralen Transformations-Proteinen entdeckt und damit das Forschungsgebiet der Verbindung zwischen Onkogenese und Kontrolle des Zellzyklus eröffnet. Ein weiterer Schwerpunkt Harlows liegt in der Epigenetik. (de) Ed Harlow (born 1952) is an American molecular biologist. Harlow received the Ph.D. degree from the Imperial Cancer Research Fund Laboratories in London. Harlow is professor of Biological Chemistry and Molecular Pharmacology at Harvard Medical School. He has been associate director of the Dana-Farber Cancer Institute as well as research director of the Massachusetts General Hospital Cancer Center and the National Cancer Institute. From 2009 to 2011 he was Chief Scientific Officer at . Among Harlow's discoveries was the demonstration that the retinoblastoma protein interacts with viral transforming proteins, thereby linking tumor viruses with the cell cycle.He is also the author, with David Lane, of "Using antibodies: a laboratory manual." (1999). Dr. Harlow has trained scientists in the field of molecular biology and oncology, including Nicholas Dyson (Professor at Harvard Medical School and Scientific Director of the Massachusetts General Hospital Cancer Center), Jacqueline Lees (Professor of Biology at MIT and associate director of the Koch Institute), (Virginia G. Piper Chair in Personalized Medicine at Arizona State University and Director of the Biodesign Institute), Matthew Meyerson (Professor of Pathology at the Dana-Farber Cancer Institute and Harvard Medical School and Senior Associate Member of the Broad Institute), Li-Huei Tsai (Picower Professor of Neuroscience at MIT and Director of the Picower Center for Learning and Memory), and (Director of the Center for Cancer Systems Biology at the Dana-Farber Cancer Institute). (en) |
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| rdfs:comment | Edward Everett Harlow (* 1952) ist ein US-amerikanischer Molekularbiologe, Genetiker und Onkologe. Harlow erwarb einen Bachelor und einen Master an der University of Oklahoma in Norman, Oklahoma und einen Ph.D. am Imperial Cancer Research Fund in London. 2009 übernahm Harlow die Funktion des Chief Scientific Officer (CSO) bei der Firma Constellation Pharmaceuticals in Cambridge, Massachusetts. (de) Ed Harlow (born 1952) is an American molecular biologist. Harlow received the Ph.D. degree from the Imperial Cancer Research Fund Laboratories in London. Harlow is professor of Biological Chemistry and Molecular Pharmacology at Harvard Medical School. He has been associate director of the Dana-Farber Cancer Institute as well as research director of the Massachusetts General Hospital Cancer Center and the National Cancer Institute. From 2009 to 2011 he was Chief Scientific Officer at . (en) |
| rdfs:label | Ed Harlow (en) Edward E. Harlow (de) |
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