Enciprazine (INN, BAN; enciprazine hydrochloride (USAN); developmental code names WY-48624, D-3112), is an anxiolytic and antipsychotic of the phenylpiperazine class which was never marketed. It shows high affinity for the α1-adrenergic receptor and 5-HT1A receptor, among other sites. The drug was initially anticipated to produce (oMeOPP), a serotonin receptor agonist with high affinity for the 5-HT1A receptor, as a significant active metabolite, but subsequent research found this not to be the case.
| Property |
Value |
| dbo:abstract |
Enciprazine (INN, BAN; enciprazine hydrochloride (USAN); developmental code names WY-48624, D-3112), is an anxiolytic and antipsychotic of the phenylpiperazine class which was never marketed. It shows high affinity for the α1-adrenergic receptor and 5-HT1A receptor, among other sites. The drug was initially anticipated to produce (oMeOPP), a serotonin receptor agonist with high affinity for the 5-HT1A receptor, as a significant active metabolite, but subsequent research found this not to be the case. (en) |
| dbo:casNumber |
68576-86-3 68576-88-5 |
| dbo:chEMBL |
101284 |
| dbo:fdaUniiCode |
L6X660925G |
| dbo:kegg |
D13112 |
| dbo:pubchem |
50222 |
| dbo:thumbnail |
wiki-commons:Special:FilePath/Enciprazine.svg?width=300 |
| dbo:wikiPageExternalLink |
http://adisinsight.springer.com/drugs/800000720 |
| dbo:wikiPageID |
54199492 (xsd:integer) |
| dbo:wikiPageLength |
4795 (xsd:nonNegativeInteger) |
| dbo:wikiPageRevisionID |
1106293101 (xsd:integer) |
| dbo:wikiPageWikiLink |
dbr:Batoprazine dbr:Oral_administration dbr:Eltoprazine dbr:Enpiprazole dbr:Ensaculin dbr:Antipsychotic dbr:Anxiolytic dbc:Phenoxypropanolamines dbc:N-(2-methoxyphenyl)piperazines dbr:Lidanserin dbr:Azaperone dbr:BMY-14802 dbr:Active_metabolite dbr:Acaprazine dbr:Agonist dbr:5-HT1A_receptor dbc:Antipsychotics dbc:Anxiolytics dbr:Alpha-1_adrenergic_receptor dbr:Fluanisone dbr:Fluprazine dbc:Pyrogallol_ethers dbr:British_Approved_Name dbr:International_Nonproprietary_Name dbr:Affinity_(pharmacology) dbr:Phenylpiperazine dbr:United_States_Adopted_Name dbr:Serotonin_receptor dbr:Mafoprazine dbr:Ortho-methoxyphenylpiperazine |
| dbp:c |
23 (xsd:integer) |
| dbp:casNumber |
68576 (xsd:integer) |
| dbp:casSupplemental |
68576 (xsd:integer) |
| dbp:chembl |
101284 (xsd:integer) |
| dbp:chemspiderid |
34991993 (xsd:integer) |
| dbp:h |
32 (xsd:integer) |
| dbp:iupacName |
1 (xsd:integer) |
| dbp:kegg |
D13112 (en) |
| dbp:n |
2 (xsd:integer) |
| dbp:o |
6 (xsd:integer) |
| dbp:pubchem |
50222 (xsd:integer) |
| dbp:routesOfAdministration |
dbr:Oral_administration |
| dbp:smiles |
COC1=CC=CC=C1N2CCNCCO (en) |
| dbp:stdinchi |
1 (xsd:integer) |
| dbp:stdinchikey |
KSQCNASWXSCJTD-UHFFFAOYSA-N (en) |
| dbp:synonyms |
WY-48624; D-3112 (en) |
| dbp:unii |
L6X660925G (en) |
| dbp:width |
250 (xsd:integer) |
| dbp:wikiPageUsesTemplate |
dbt:Adrenergic_receptor_modulators dbt:Drugbox dbt:Reflist dbt:Serotonin_receptor_modulators dbt:Short_description dbt:Anxiolytic-stub |
| dcterms:subject |
dbc:Phenoxypropanolamines dbc:N-(2-methoxyphenyl)piperazines dbc:Antipsychotics dbc:Anxiolytics dbc:Pyrogallol_ethers |
| rdf:type |
owl:Thing dul:ChemicalObject dbo:ChemicalSubstance wikidata:Q8386 dbo:Drug |
| rdfs:comment |
Enciprazine (INN, BAN; enciprazine hydrochloride (USAN); developmental code names WY-48624, D-3112), is an anxiolytic and antipsychotic of the phenylpiperazine class which was never marketed. It shows high affinity for the α1-adrenergic receptor and 5-HT1A receptor, among other sites. The drug was initially anticipated to produce (oMeOPP), a serotonin receptor agonist with high affinity for the 5-HT1A receptor, as a significant active metabolite, but subsequent research found this not to be the case. (en) |
| rdfs:label |
Enciprazine (en) |
| owl:sameAs |
wikidata:Enciprazine dbpedia-fa:Enciprazine https://global.dbpedia.org/id/2YrTV |
| prov:wasDerivedFrom |
wikipedia-en:Enciprazine?oldid=1106293101&ns=0 |
| foaf:depiction |
wiki-commons:Special:FilePath/Enciprazine.svg |
| foaf:isPrimaryTopicOf |
wikipedia-en:Enciprazine |
| is dbo:wikiPageRedirects of |
dbr:C23H32N2O6 dbr:D-3112 dbr:D3112 dbr:D_3112 dbr:WY-48,624 dbr:WY-48624 dbr:WY48624 dbr:WY_48,624 dbr:WY_48624 dbr:Wy-48,624 dbr:Wy48624 dbr:Wy_48,624 dbr:Wy_48624 |
| is dbo:wikiPageWikiLink of |
dbr:Enpiprazole dbr:Ensaculin dbr:Azaperone dbr:BMY-14802 dbr:C23H32N2O6 dbr:Acaprazine dbr:Fluanisone dbr:D-3112 dbr:D3112 dbr:Substituted_piperazine dbr:List_of_drugs:_Em–Ep dbr:D_3112 dbr:WY-48,624 dbr:WY-48624 dbr:WY48624 dbr:WY_48,624 dbr:WY_48624 dbr:Wy-48,624 dbr:Wy48624 dbr:Wy_48,624 dbr:Wy_48624 |
| is foaf:primaryTopic of |
wikipedia-en:Enciprazine |
