Enolase superfamily (original) (raw)

The enolase superfamily is a superfamily of enzymes, members of which catalyse a range of reactions. The enolase superfamily includes enzymes that catalyse a wide variety of reactions and performing diverse roles in metabolism. However, the reactions catalysed share the common chemical step of abstraction of a proton from a carbon adjacent to a carboxylic acid and a requirement of a divalent metal ion. This diversity of functions is in contrast to many families of enzymes whose members catalyse similar chemical reactions on different substrates.