Epix Pharmaceuticals (original) (raw)

Epix Pharmaceuticals Inc (formerly Predix Pharmaceuticals Inc) was a pharmaceutical company based in Lexington, Massachusetts. Its products included the following agents: * PRX-00023—5-HT1A receptor full agonist (later discovered to be an antagonist): for major depression and generalized anxiety disorder * PRX-03140—5-HT4 receptor partial agonist: for Alzheimer's disease * PRX-07034—5-HT6 receptor antagonist: for obesity and cognitive impairment associated with Alzheimer's disease and schizophrenia * PRX-08066—5-HT2B receptor antagonist: for pulmonary hypertension associated with chronic obstructive pulmonary disease