Estrobin, also known as α,α-di(p-ethoxyphenyl)-β-phenylbromoethylene and commonly abbreviated as DBE, is a synthetic, nonsteroidal estrogen of the triphenylethylene group that was never marketed. Chlorotrianisene, and subsequently clomifene and tamoxifen, were derived from it. Estrobin, similarly to other triphenylethylenes, is very lipophilic and hence very long-lasting in its duration of action. Similarly to chlorotrianisene, estrobin behaves a prodrug to a much more potent estrogen in the body.
| Property |
Value |
| dbo:abstract |
Estrobin, also known as α,α-di(p-ethoxyphenyl)-β-phenylbromoethylene and commonly abbreviated as DBE, is a synthetic, nonsteroidal estrogen of the triphenylethylene group that was never marketed. Chlorotrianisene, and subsequently clomifene and tamoxifen, were derived from it. Estrobin, similarly to other triphenylethylenes, is very lipophilic and hence very long-lasting in its duration of action. Similarly to chlorotrianisene, estrobin behaves a prodrug to a much more potent estrogen in the body. (en) |
| dbo:casNumber |
60883-74-1 |
| dbo:fdaUniiCode |
MM7V5ZUU9B |
| dbo:pubchem |
109030 |
| dbo:thumbnail |
wiki-commons:Special:FilePath/Estrobin.svg?width=300 |
| dbo:wikiPageID |
48940369 (xsd:integer) |
| dbo:wikiPageLength |
2904 (xsd:nonNegativeInteger) |
| dbo:wikiPageRevisionID |
1093575146 (xsd:integer) |
| dbo:wikiPageWikiLink |
dbr:M2613 dbr:Nonsteroid dbc:Organobromides dbc:Prodrugs dbc:Synthetic_estrogens dbr:Estrogen dbr:Organic_compound dbr:Clomifene dbr:Lipophilic dbr:Stilbestrol dbr:Prodrug dbr:Triphenylethylene dbc:Triphenylethylenes dbr:Broparestrol dbr:2,8-Dihydroxyhexahydrochrysene dbc:Selective_estrogen_receptor_modulators dbr:Tamoxifen dbr:Chlorotrianisene dbr:Diethylstilbestrol dbr:Ethamoxytriphetol |
| dbp:atcPrefix |
None (en) |
| dbp:br |
1 (xsd:integer) |
| dbp:c |
24 (xsd:integer) |
| dbp:casNumber |
60883 (xsd:integer) |
| dbp:chemspiderid |
98048 (xsd:integer) |
| dbp:h |
23 (xsd:integer) |
| dbp:iupacName |
11 (xsd:integer) |
| dbp:o |
2 (xsd:integer) |
| dbp:pubchem |
109030 (xsd:integer) |
| dbp:unii |
MM7V5ZUU9B (en) |
| dbp:wikiPageUsesTemplate |
dbt:Drugbox dbt:Estrogenics dbt:Genito-urinary-drug-stub dbt:Reflist dbt:Short_description dbt:Cascite dbt:Fdacite |
| dcterms:subject |
dbc:Organobromides dbc:Prodrugs dbc:Synthetic_estrogens dbc:Triphenylethylenes dbc:Selective_estrogen_receptor_modulators |
| gold:hypernym |
dbr:Estrogen |
| rdf:type |
owl:Thing dul:ChemicalObject dbo:ChemicalSubstance wikidata:Q8386 dbo:Drug |
| rdfs:comment |
Estrobin, also known as α,α-di(p-ethoxyphenyl)-β-phenylbromoethylene and commonly abbreviated as DBE, is a synthetic, nonsteroidal estrogen of the triphenylethylene group that was never marketed. Chlorotrianisene, and subsequently clomifene and tamoxifen, were derived from it. Estrobin, similarly to other triphenylethylenes, is very lipophilic and hence very long-lasting in its duration of action. Similarly to chlorotrianisene, estrobin behaves a prodrug to a much more potent estrogen in the body. (en) |
| rdfs:label |
Estrobin (en) |
| owl:sameAs |
yago-res:Estrobin wikidata:Estrobin https://global.dbpedia.org/id/2Mra6 |
| prov:wasDerivedFrom |
wikipedia-en:Estrobin?oldid=1093575146&ns=0 |
| foaf:depiction |
wiki-commons:Special:FilePath/Estrobin.svg |
| foaf:isPrimaryTopicOf |
wikipedia-en:Estrobin |
| is dbo:wikiPageRedirects of |
dbr:DBE_(drug) |
| is dbo:wikiPageWikiLink of |
dbr:M2613 dbr:Stilbestrol dbr:Triphenylchloroethylene dbr:Triphenylethylene dbr:DBE_(drug) dbr:Nonsteroidal dbr:2,8-Dihydroxyhexahydrochrysene dbr:Chlorotrianisene dbr:Ethamoxytriphetol dbr:Nonsteroidal_estrogen dbr:Triphenylbromoethylene dbr:Triphenyliodoethylene |
| is foaf:primaryTopic of |
wikipedia-en:Estrobin |
